Stargardt a matenda: malongosoledwe osiyanasiyana, zizindikiro ndi mbali chithandizo

matenda Stargardt ndi ndondomeko osachiritsika amakwiya mu macula lapansi. Pali ambiri matenda chipatala omwe ndi ofanana ndi kudwala izi. Iwo amayamba ndi kusintha kwa majini osiyanasiyana. Choncho, matenda ali m'gulu la pathologies cholowa.

Waukulu matenda chiwonetsero cha matenda ndi ndondomeko osachiritsika mu macula ndi pakati retinitis pigment kuchititsa dontho la chitukuko cha scotoma chapakati.

Features matendawa

matenda Stargardt ndi osowa koma kwambiri pathologies. Izo kumaonekera ali mwana - kuchokera zaka 6 mpaka 20 ndi pafupipafupi 1: 20,000. Mu zina siyana zaka kudwala, monga ulamuliro, osati vstrechvaetsya. Zotsatira za matenda owononga. Salamulidwa kunja imfa wathunthu wa masomphenya.

Matendawa ali ndi maziko chibadwa. Dystrophic ndondomeko amakhudza retinal macular dera ndi zimachokera ku pigment epithelium, imbaenda khungu. ndondomeko ndi amgwirizano.

mawonekedwe pathological

Pali kugawinikana bwino kudwala ku mitundu zinayi malingana ndi dera yotupa kutanthauzira:

Osachiritsika ndondomeko zingaoneke:

• pakati woyendera nthambi zotumphukira;
• m'dera macular;
• mu zone ya paracentral.

Komanso, pali mtundu wosanganiza cha matenda kumafuna kutupa isanafalikire m'chigawo chapakati diso pa periphery wa.

Zimagwirira chitukuko matenda

The zimayambitsa matenda akukambidwa dokotala Karl Stargardt mu zoyambirira za mazana makumi awiri. Pomulemekeza dzina matenda. kudwala ndi wachibale dera macular ndiponso malinga ndi wasayansi, ndi anasamutsidwa mu cholowa banja. Kawirikawiri anasankha polymorphic ophthalmoscopic chithunzi, lomwe lili ndi dzina la "manja a choroid" ndiponso "diso ng'ombeyo", "mkuwa wosweka" ndi ena.

Kudzera Pamalo cloning mbuye jini locus anazindikiritsidwa zimene zimachititsa retinitis pigmentosa, zimaoneka kwambiri maselowa lapansi. Mu sayansi umatchedwa ABCR.

matenda diso ndi tinatengera mu autosomal unsembe lalikulu. Pakuti pathologies yodziwika ndi kutanthauzira za chibadwa mutated mu DNA 13q ndi 6ql4.

Maziko majini sayendera jenda. Malinga ndi kafukufuku wa posachedwapa wa zachibadwa doctor-, ndi mtundu wamphamvu wa kufala kwa matenda, pamafunika pang'ono mosavuta, ndipo sikuti kuyambitsa khungu. zolandilira kwambiri selo kupitiriza kugwira ncthito. Odwala awa, kudwala amapezeka ndi zizindikiro kochepa. Anakhudzidwa akugwirabe ntchito ndi kuthekera galimoto galimoto.

Kodi matenda Stargardt chiyani? Zimayambitsa alibe macular maselo kugona mu kusowa mphamvu. Gene chilema amakwiya yopanga mapuloteni zosalongosoka amene anasamutsidwa ATP mamolekyulu mwa selo nembanemba macular chigawo chapakati cha diso. Iwo ankaganizira chithunzi zithunzi ndi mtundu.

symptomatology kudwala

ndi makhalidwe a anthu ndi matenda Stargardt n'chiyani? Ndi chitukuko cha kudwala matenda si anati mu ziwalo zina za m'kati. ndondomeko amakhudza yekha maso. Matendawa amayamba ndi kufa acuity zithunzi. Kenako zizindikiro ndi kuwonjezeka ndipo pali zinthu zotsutsana kwambiri ndi maganizo a mtundu wonse wa view anazindikira za uthunthu kawalidwe.

kusintha osachiritsika a fundus ndi tikuonera kanjedza zotsatirazi:

• m'maso onse amalembedwa inki zozungulira dontho mawonekedwe;
• pali malo m'dera lopanda pigment;
• ananena atrophic ndondomeko mu retinal pigment epithelium.

njira amenewa kumachitika molumikizana ndi pakutchulidwa mawanga yochitidwa-chikasu. Monga matenda ili m'kati mu retinal pigment epithelium anaulula chodziwa kudzikundikira chuma lipofuscin ngati.

odwala onse anakhudzidwa ndi kudwala ichi, wapezeka mtheradi kapena tsankho chapakati scotoma, amene makhalidwe osiyana, chifukwa cha kuchuluka kwa ndondomekoyi.

Pamene zheltopyatnistoy mphako bokosi la wodwala anthu akhoza kukhala mu osiyanasiyana wabwinobwino, koma masomphenya chapakati ndi ndinasintha yafupika.

Ambiri a milandu ya anthu amene akukonza ndi kafukufuku, izo tinaonera kuphwanya maganizo a mitundu deuteranopia mtundu, red-wobiriwira diskhromazii. Pamene zheltopyatnistom dystrophic ndondomeko ya masomphenya mtundu akhoza kukhala sasintha kwathunthu.

Dystrophy Stargardt amaloŵamo kusintha okhudza malo pafupipafupi kusiyana osiyanasiyana (mu ndondomeko magawo 6 - 10 º ndi kuchepetsa kwambiri m'dera la mafurikwense pakati okhudza malo ndi anasiya dera mkulu pafupipafupi). syndrome amatchedwa "chitsanzo cha phirilo dystrophy."

Zizindikiro monga masomphenya wavy wa zinthu, mawanga akhungu, blurriness, mtundu kulakwila movutikira anatengera pamaso pa Kuwala kochepa.

matenda matenda

Chifukwa cha kafukufuku pa mlingo majini zavumbulutsidwa umboni kuti diso matenda Stargardt anatsimikiza matenda allelic locus ABCR.

Matenda a matenda ikuyamba ndi phunziro la dziko la fundus lapansi. Anachita fluorescein angiography wa retinal mtima zoona electrophysiological. Pankhaniyi, mtima wa mlingo wa kuwonongeka chofunika. Izi zimathandiza kudziwa angapo zizindikiro matenda, kuphatikizapo matumba giperflyuorestsiruyuschie ndi kuwala kwa mitsempha chamawonedwe.

Popeza matenda ndi cholowa chikhalidwe, njira yolondola kwambiri kudziwa matenda ikanakhala nthawi DNA, amene amatha kuzindikira matenda otengera monomonogennye.

matenda masiyanidwe

matenda Stargardt iyenera kukhala kulekana kwa phirilo ndodo kukhala ndi wa phirilo ndi Wand kwa phirilo dystrophy, mwapang'onopang'ono foveal dystrophy, lalikulu, Ana Retinoschisis, macular dystrophy vitelliformnoy.

Komanso, masiyanidwe matenda akuonetsedwa ngati mimba toxemia anapeza chifukwa mlingo alibe (makamaka pamene hlorokvinovoy retinopathy).

Kodi kudzachiritsidwa matenda Stargardt chiyani?

mankhwala Etiologic kulibe. Iwo kumatha matenda Stargardt chiyani? wothandiza khalidwe Chithandizo zimaphatikizapo kugwiritsa parabulbar jekeseni wa taurine ndi antioxidants oyamba zikutanthauza anakafika nsupa (pentoxifylline, asidi nicotinic), ndi mankhwala.

mavitamini Popanda kuchitapo kanthu kuti kulimbikitsa chotengera khoma ndi bwino kuti magazi aziyenda bwino. mavitamini ambiri ntchito B, A, C, E.

Imasonyezedwa atagwira physiotherapy. Pakati pawo tiyenera kuunikila electrophoresis mankhwala osokoneza bongo ndipo retinal kukondoweza mwa laser.

Ntchito revasulyarizatsiya diso ndi kupatsidwa zina ndi macular m'dera ulusi minofu.

Poyamba ophthalmologists padziko lonse anali kukhulupirira kuti matenda si mankhwala. Njira pamwamba kuthandiza kwangochepetsako pang'ono chabe sachedwa kudwala matendawa, koma mu nkhani palibe sizimathandiza kupewa izo.

Monga ulamuliro, mankhwala sanali kupulumutsa anthu ku imfa lathunthu la masomphenya. Amafuna kukhala njira kuti kuti atsogolere kubwezeretsedwa kwa nyumba zowonongeka ocular.

Nzeru njira ya mankhwala

Kodi pali panopa njira zothandiza kuchotsa kudwala monga matenda Stargardt chiyani? Kodi kuchiza matenda aakulu? njira wakhala akufuna mu 2009 Dr. Aleksandrom Dmitrievichem Romaschenko, yemwe ndi mutu wa pochiza matenda a maso Center "ON Clinic" (Saint-Petersburg, up. Marata, nyumba 69, kumanga B). Iwo anali bwino njira matenda chithandizo zochokera ma minofu chithandizo.

Chifukwa cha mankhwala ntchito maselo tsinde la adipose minofu matenda munthu. The njira achire anayamba kupanga asayansi kale VP Filatov. Chifukwa cha umisiri wotsogola pa odwala apatsidwa mwayi kuti abwezeretse masomphenya anatayika amapereka moyo wathunthu.

Dr. AD anawalemba Romashchenko zovuta luso Biomedical ndi setifiketi njira zotsatirazi mankhwala maselo :

• ophatikizana njira yochotsa mawonekedwe yonyowa matendawa;
• zovuta njira paitogeneticheskogo pakati mankhwala ndi tapetoretinalnoy dystrophy.

Pa chipatala limodzi ndi mankhwala?

Zochizira matenda zovuta wakhala ophthalmologic pakati "Pa Clinic". pakati lili mumzinda ngati St. Petersburg. Kuchiza matenda Stargardt a zitha kukhala pa malowa, chifukwa ndi yekhayo mu Russia, kumene sayansi otere ntchito.

Kodi maselo mankhwala ndi otetezedwa?

Akatswiri angathe zimatsimikizira kuti luso mankhwala anayamba AD Romashchenko, ndi otetezeka kwambiri. Zochizira maselo wodwalayo ntchito, zomwe kumatha kuthekera kukanidwa kapena mavuto ena negative.

Pomaliza

matenda Shtargradta kuwonekera koyamba kugulu ali wamng'ono ndipo mwamsanga kutsogolera imfa mtheradi wa masomphenya. Nthawi zina kwambiri, cholowa lalikulu mtundu, m'maso pang'onopang'ono. Odwala akulangizidwa kuti akakumane ndi maso, mavitamini ndi kuvala magalasi. The njira yabwino kwambiri kuthetsa kudwala ankaona mankhwala ndi maselo tsinde.