Kumatanthauza yakuti "Tranexamic Acid" ndi mankhwala antifibrinolytic, odana ndi yotupa ndi antiallergic kanthu, komanso kutchulidwa zotsatira hemostatic pamene bleedings amene amagwirizana ndi kuwonjezeka mu fibrinolysis. Pa maziko a mankhwala ndi chopinga wa plasminogen activator ndi plasmin chopinga wa mapangidwe mapeputisayidi udakali kinins mwachindunji m'zochitika zosiyanasiyana yotupa ndi matupi awo sagwirizana. Komanso, chida monga "asidi Tranexamic", kwambiri lengthens ndi thrombin nthawi. Ndi nkhani ya makhalidwe pharmacokinetics wa mankhwala odana fibrinolytic pambuyo ingestion ndi odzipereka 30-50% ya dosing koyamba, wapamwamba ananena plasma woipa zana - Mphindi zana ndi makumi asanu ndi atatu pambuyo ntchito. Antifibrinolytic anachita zimakhala anasunga fifitini - maola khumi ndi zisanu ndi ziwiri, ndi madzi a m'magazi - maola asanu ndi awiri kapena asanu ndi atatu pambuyo utsogoleli wa mankhwala "asidi Tranexamic". Mtengo wa chida ichi ndi 1300 rubles, ndipo mugule izo pafupifupi ogulitsa mankhawala.
Antifibrinolytic mankhwala amapangidwa mu mawonekedwe a mapiritsi a mazana awiri ndi makumi asanu kapena faifi handiredi milligram, monga njira jekeseni, komanso njira anafuna makonzedwe m'kamwa. Onse a mitundu pamwamba mlingo ndi loyenereradi mankhwala ndi kupewa magazi, chikwiyire kuwonjezeka mu fibrinolysis wonse. Mwachitsanzo, nthawi zambiri kutumikiridwa wothandizira, hereinafter amatchedwa "asidi Tranexamic" mu zotupa zilonda za Prostate kapena kapamba, khansa, opaleshoni zikunena pa ziwalo chifuwa, ndi matenda chiwindi. Buku kuchotsa nsengwa ndi postpartum kukha mwazi ali m'gulu mndandanda wa zikuonetsa kuti akupita. Komanso, kugwiritsa ntchito mankhwala "asidi Tranexamic" ziyenera haematuria, angioedema, matupi awo sagwirizana dermatitis, chikanga, poizoni ndi mankhwala totupa, ming'oma. Komanso, mankhwala akusonyeza kuti pharyngitis yogwira, laryngitis, zilonda zapakhosi, stomatitis, m'mphuno, uterine ndi magazi m'mimba, dzino m'zigawo odwala matenda ndi hemorrhagic diathesis. Komanso kuti chida monga "asidi Tranexamic", ndi mwezi, ena kuposa mvula.
Koma ntchito yeniyeni ndi n'zimene mankhwala pa nkhani iliyonse alili payekha, zochokera zinthu linaperekedwa matenda. Komabe, monga ulamuliro, pa nthawi amaloledwa kutenga mu palibe magilamu 1-1.5. Mu nkhani iyi, ntchito ya multiplicity nthawi awiri ndi anai pa tsiku, ndi nthawi ya mankhwala - kwa masiku atatu mpaka fifitini. Single mlingo makonzedwe mtsempha ndi 10-15 mg / kg.
The contraindications waukulu kugwiritsa ntchito chida ichi ndi zinthu monga kukha mwazi subarachnoid, thromboembolism, kulephera aimpso, mkhutu mtundu kuzindikira, ndi thrombosis kwambiri m'mitsempha. Komanso, sayenera kugwiritsa ntchito mankhwala ngati hypersensitivity payekha kapena mimba. Zotsatira zoyipa kugwirizana ndi madyedwe a wothandizila odana fibrinolytic, kudzaonekera pamene chizungulire, tulo, hypotension, tachycardia, kufooka, ndipo ululu pachifuwa.