"Seroquel": ndemanga. "Seroquel": malangizo othandizira, zizindikiro

Mwamwayi, mavuto osiyanasiyana a psychotic ndi ofala kwambiri masiku ano. Ndipo, ndithudi, anthu omwe ali ndi mavutowa amafunikira chithandizo chokwanira komanso chokwanira. Mankhwala amasiku ano amapereka mankhwala ochuluka omwe angathe kuthana ndi mavuto amenewa kapena kuchepetsa vuto la wodwalayo. Ndipo kusankha bwino ndi mankhwala "Seroquel". Maphunziro a akatswiri ndi odwala amasonyeza kuti mankhwala amathandizadi. Koma nchiyani chomwe chikuphatikizidwa mu dongosolo lake? Kodi pali mankhwala otsutsana ndi mankhwala? Kodi mapiritsi ndi angati? Nkhaniyi idzakhala yosangalatsa kwa owerenga ambiri.

Maonekedwe ndi mawonekedwe a mankhwala

Kawirikawiri, mndandanda wa mankhwala omwe amaperekedwa kwa odwala omwe ali ndi matenda ena amtima umaphatikizapo mankhwala a Seroquel. Mankhwalawa amapezeka ngati mapiritsi ang'onoang'ono omwe ali ndi chikopa choyera, pinki kapena chikasu (malingana ndi mlingo).

Chinthu chofunika kwambiri apa nditiapine mwa mawonekedwe a fumarate. Mpaka pano, mapiritsi alipo ndi mlingo wa 25, 50, 100 ndi 200 mg wa chigawo ichi. Mwachibadwa, zinthu zina zimagwiritsidwa ntchito popanga makina, makamaka povidone, microcrystalline mapadi, lactose monohydrate, calcium hydrogenphosphate, magnesium stearate ndi sodium carboxymethyl starch.

Chombochi chimakhala ndi titanium dioxide, macrogol 400, hypromellose, komanso utoto - okosidi wofiira kapena wachikasu.

Komanso, palinso mankhwala "Seroquel Prolong", omwe amapereka zotsatira zowonjezereka. Amapezekanso pamapiritsi, koma biconvex ndi mawonekedwe oblong. Pali mapiritsi okhala ndi 50, 150, 200 ndi 400 mg ya mankhwala othandizira (apa mbali iyi imasewedwanso ndi quetiapine).

Monga zinthu zothandiza, microcrystalline cellulose, sodium citrate dihydrate, magnesium stearate, lactose monohydrate ndi hypromellose alipo pano. Mapiritsi amaikidwa mu mabelters a zidutswa 10. Mu phukusi limodzi muli matayala asanu ndi limodzi.

Main pharmacological katundu

Mankhwalawa ndi a neuroleptic (antipsychotic) a m'badwo watsopano. Pa kafukufuku, anapeza kuti chigawo chachikulu chogwiritsira ntchito chikuwonetsa mgwirizano wapatali ndi ena obwezera serotonin mu ubongo. Mankhwalawa amakhudzanso histamine, komanso alpha-1 ndi alpha-2-adrenoreceptors.

Mankhwalawa ndi abwino ndipo mwamsanga amatengeka ndi makoma a chigawo cha m'mimba. Zachigawo zikuluzikulu zimakhudzana ndi mapuloteni a magazi pafupifupi 83%. Quetiapine imagwiritsidwa ntchito m'magazi a chiwindi, kumene imasandulika kukhala metabolites angapo popanda ntchito yamagetsi. Ambiri a metabolite amawasokoneza ndi impso (pafupifupi 73%), ang'onoang'ono - pamodzi ndi ana a ng'ombe. Pafupifupi 5 peresenti ya ketiapine imatulutsidwa kuchokera mu thupi pa msinkhu wake wosasinthika.

Zizindikiro zazikulu zogwiritsidwa ntchito

Ndipotu, pali zinthu zambiri pamene kumwa mankhwalawa n'kofunikira. Mwachitsanzo, ngati mukufuna kudziwa mmene mungachiritse matenda a schizophrenia, ndi bwino kudziwa kuti ndi mankhwalawa omwe ali mbali ya mankhwalawa.

Kuonjezera apo, mankhwalawa "Seroquel" amagwiritsidwa ntchito kwambiri kuti athetse vuto lachisokonezo chokwanira komanso chachikulu (kuphatikizapo mankhwala ena, ndithudi). Amaperekedwanso kwa odwala omwe ali ndi maganizo ovuta komanso ovuta a chiyambi.

Mankhwalawa "Seroquel": malangizo othandizira

Musagwiritse ntchito mankhwalawa. Dokotala yekha amadziwa mmene angachiritse schizophrenia, psychoses ndi mavuto ena - kudzipiritsa kuno kumangopweteka kwambiri.

Nthawi yomweyo muyenera kudziŵa kuti mlingo ndi nthawi ya mankhwala zimatsimikiziridwa payekha. Dokotala yekha angakuuzeni momwe mungatengere bwino "Seroquel Prolong". Malangizowa ali ndi zowonjezera zokhazokha.

Kawirikawiri, mankhwalawa akuyendetsedwa, kuyambira ndi tizilombo tochepa, pang'onopang'ono kuwonjezera kuchuluka kwa mankhwala opangira. Mwachitsanzo, mu psychoses ndi schizophrenia tsiku loyamba, wodwala amalandira 50 mg ya quetiapine, 100 mg yotsatira, ndi 200, 300, ndi zina zotero. Mlingo wa tsiku ndi tsiku ndi 750 mg, ngakhale pano zonse zimadalira kulekerera kwa mankhwala ndi kuopsa kwake. Chiwembu cha mankhwala odwala matenda ovutika maganizo amawoneka mofanana (mlingo wa tsiku ndi tsiku ndi 600 mg). Koma ndi maganizo a manic, mankhwala amayamba ndi 100 mg ya mankhwala.

Kwa odwala okalamba, mlingo woyambirira ndi 25 mg, tsiku ndi tsiku amawonjezeka ndi 25-50 mg, malinga ndi momwe thupi limayendera. Mwa njira, muyenera kumwa mapiritsi kamodzi patsiku.

Kodi pali zotsutsana ndi mankhwala?

Chodabwitsa kwambiri ndi funso lakuti kaya magulu onse a odwala angatenge mankhwala otani Seroquel. Malingaliro a madokotala amatsimikizira kuti mankhwalawa alibe zotsutsana zambiri. Poyambira ndi koyenera kunena, mapiritsi sangathe kuvomerezedwa ngati mwakuya kwanu muli zovuta zina. Komanso, mankhwalawa sayenera kuledzera ndi cytochrome P450 inhibitors (awa ndiwo mankhwala enaake, makamaka erythromycin, komanso protease inhibitors ndi mankhwala ena osokoneza bongo). Kuchita bwino ndi zotsatira zowononga za mapiritsi pochiza amayi oyembekezera ndi ana akadali pa siteji yophunzira.

Kodi ndingatenge mankhwala kwa amayi apakati?

Ambiri akukhudzidwa ndi funso loti ngati n'zotheka kutenga mapiritsi a "Seroquel" kapena "Seroquel Prolong" panthawi yoyembekezera? Malangizo ogwiritsira ntchito amanena kuti zotsatira za mankhwala omwe ali pa mwana wosabadwa sanaphunzirepo. Mankhwala amatha kuuzidwa kokha ngati zomwe zimapindulitsa mkazi zimakhala zopambana kusiyana ndi msinkhu wotheka kuti thupi la mwana yemwe akukula likhale loopsa.

Pa nthawi ya lactation, ndi bwino kusiya kuyamwitsa panthawi yopatsira chithandizo, chifukwa choti nthawi yomwe amamasulidwa ndi mankhwala omwe amapezeka ndi mkaka wa m'mawere sanagwiritsidwe ntchito.

Kodi ndi zoopsa ziti zomwe zimagwiritsidwa ntchito ndi mankhwala? Zotsatira zokayikitsa

Kodi pali zotsatira zina zomwe zimalandira mapiritsi a "Seroquel"? Umboni wa odwalawo umasonyeza kuti zovuta ndizochepa, ndipo zimakhala zochepa. Komabe, nkofunika kudzidziwitsa nokha ndi mndandanda wawo kuti awone kuwonongeka kwa nthawi.

Nthaŵi zambiri odwala amadandaula za kugona. Matenda ena amatha kumbali ya dongosolo lamanjenje: chizunguliro, kutaya mtima, vuto la vegetative-vascular, kuthamanga kwa minofu. Chithandizo chochepa kawirikawiri chikuphatikizidwa ndi ziphuphu.

Kusokonezeka kwa dongosolo la m'mimba nthawi zina kumachitika. Izi nthawi zambiri zimamangiriridwa kapena kutaya . Kawirikawiri pali kuwonjezeka kwa mlingo wa triglycerides ndi cholesterol m'magazi, komanso kuwonjezeka kwa ntchito ya mavitamini odziteteza.

Pa nthawi yoyamba, dokotala akamangosankha mlingo, pakhoza kukhala zinthu monga chizungulire chokhudzana ndi kuchepetsa kuthamanga kwa magazi, komanso tachycardia ndi kutaya. Monga lamulo, kuchepa kwa mlingo wa tsiku ndi tsiku, zizindikirozi zimatha pokhapokha.

Mwachidziwikire, zimakhala zotheka kuchitapo kanthu, makamaka pokhala ndi hypersensitivity kwa mankhwala ena. Zosokoneza zimaphatikizapo kudzikuza, ming†™ oma, maonekedwe a khungu ndi kuphulika, nthawi zambiri - angioedema ndi anaphylactic shock.

Nthawi zina, phokoso la edema likuwonekera pambuyo pa mankhwala. Odwala ena amafotokoza kulemera kolemera. Mankhwalawa angakhudze ntchito ya chithokomiro, kuchepetsa kukula kwa mahomoni akuluakulu.

Overdose, zizindikiro zake ndi mankhwala

Nthawi yomweyo tiyenera kutchula kuti kuchipatala milandu yochepa kwambiri ya mankhwala osokoneza bongo amalembedwa. Zoonadi, mavuto aakulu adawonedwa kokha pamene wodwalayo anatenga magalamu makumi awiri a timu timene timakhala timeneti panthawi imodzi.

Zizindikiro za kupitirira muyezo ndi kuwonjezeka kwa zotsatira zovuta kwambiri zomwe zimachitikapo kuphatikizapo kuchepa kwakukulu kwa magazi, kugona kwakukulu, ndi tachycardia. Thandizo loyamba limachepetsedwa kuti lisambe m'mimba ndi kutenga ziwombankhanga, ngakhale izi zimakhala zothandiza kokha ngati mankhwalawa asanakhale nawo nthawi yokumba pamakoma a kapangidwe kake. M'tsogolomu, chithandizo chamankhwala chikuchitika, chomwe chikuwathandiza kuthandizira kugwira bwino ntchito za kupuma, miyendo ya mtima ndi yapamwamba .

Zofanana analogues za mankhwala

Pazifukwa zina, si odwala onse omwe ali oyenera mankhwalawa. Apo pali funso lodziwika bwino: kodi n'zotheka kulisintha ndi chinachake? Inde, ambiri antipsychotics ali ndi zotsatira zofanana. Komanso, ena amakhalanso ndi zinthu zofanana. Mwachitsanzo, mapiritsi a Quentiax ali ndi zofanana ndi katundu.

Palinso mafananidwe ena abwino. Mankhwala monga Lakvel, Ketiap, Nantarid, Servitor, Cvetitex ndi ena ambiri amaonedwa kuti ndi othandiza. Mwa njira, ena a iwo amawononga pang'ono.

Koma mulimonsemo nkofunikira kumvetsetsa kuti dokotala yekha amene akupezekapo angasinthe mndandanda wa mankhwala omwe mwauzidwa - sankhani mafananidwe kapena mutenge mankhwala aliwonse popanda kudziwa katswiri wotsutsana kwambiri.

Kodi mankhwalawa ndi ochuluka bwanji?

Kwa odwala ambiri, funso la mtengo wa mankhwala opatsidwa ndilofunika kwambiri. Ndiye ndikutengako kuchuluka kwa mapiritsi a "Seroquel"? Mtengo, ndithudi, umadalira pa zinthu zambiri, kuphatikizapo wopanga, ndondomeko yachuma ya mankhwala ndi mlingo.

Mwachitsanzo, mapiritsi okhala ndi 25 mg yogwiritsira ntchito mankhwala amawononga pafupifupi 1600-1800 rubles. Mankhwala omwe ali ndi mlingo wa 100 mg adzalandira zambiri - malire ake amtengo wochokera ku 3000 mpaka 3600 ruble. Mapiritsi omwe ali ndi mlingo wa 200 mg mtengo wa ma ruble 5500-6000.

Kuyika mkaka wa mankhwala "Seroquel Prolong" ndi mlingo wa 200 mg wa chogwiritsiridwa ntchito kumatenga ndalama zokwana 7500-8000. Koma mapiritsi okhala ndi mlingo waukulu (400 mg) amawononga ndalama zoposa 15,000 za ruble. Inde, mitengoyi ndi yapamwamba, komabe nthawi zina ndalama zotere zimangokhala zofunika.

Ndemanga za mankhwala

Lero, odwala ambiri omwe akudwala matendawa kapena ena, madokotala amaika chimodzimodzi "Seroquel". Ndemanga za akatswiri za mankhwalawa ndi zabwino kwambiri. Ndi mbadwo watsopanowu mankhwala omwe amachititsa thupi mosalekeza popanda kuchititsa mavuto aakulu. Ngakhale zomwe zimachitika monga kugona ndi mavuto ndi chidwi, zimawonetseredwa kawirikawiri.

Kodi odwala okhawo amanena chiyani za mankhwalawa "Seroquel"? Mayankho a odwalawo amadziwikiratu. Mankhwalawa kuphatikizapo mankhwala ena amathandiza kuthetseratu mavuto ambiri ndikukhala bwino. Inde, mwa anthu ena, mapiritsi amachititsa kutopa, kugona ndi kulemera kwa kusintha. Ngati panthawi yomwe mukudwala mukusintha mkhalidwe wanu, ndiye mwamsanga funsani dokotala - mungafunike mankhwala ena. Zolakwitsa za mankhwala zingawonenso chifukwa cha mtengo wake wokwera. Komabe, zotsatira za mankhwala zimapereka ndalama iliyonse.