"Pentoxifylline": analogues, malangizo ntchito, mitengo weniweni

Mankhwala akhoza m'malo ndi "Pentoxifylline?" An analogue mankhwala Adzaperekedwa ku zipangizo nkhani. Kuyambira mungathe kuphunzira zimene zikunenedwa anatanthauza mitundu medicament imene chogulitsidwa, mmene ayenera kugwiritsidwa ntchito, ndi zina zotero.

The zikuchokera, mawonekedwe, ma CD

Mu mawonekedwe zomwe chogulitsidwa mankhwala "Pentoxifylline?" Malangizo ntchito (analogues wa mankhwala angapezeke mu ogulitsa mankhawala aliyense) akusonyeza kuti mankhwala lilipo zosiyanasiyana, akuti:

• Mapiritsi (400 ndi 100 mg) ndi TACHIMATA pinki. Mu katoni imodzi anyamula zidutswa 60 kapena 20.
• The pellets (400 ndi 100 mg). The paketi ma CD a makatoni mwina 60 kapena 20 zidutswa.
• Mapiritsi, kanthu yaitali (600 400 mg) ndi TACHIMATA ndi enteric TACHIMATA ndi mzere kugawanika. The ma CD katoni zambiri lili zidutswa 50.
• Mbale ndi njira jekeseni. The zikuchokera chiphunzitso zimenezi zimaphatikizapo pentoxifylline ndi sodium kolorayidi ndi madzi.

mbali pharmacological

Kodi katundu Kodi mankhwala "Pentoxifylline?" Analogue wosauka uyu ali ndi makhalidwe omwewo monga anati medicament yekha. Adzaupereka kwa latsopano pharmacological ndalama gulu hemorheological. Iye akhoza kukonzanso plasticity maselo a magazi ndi kuchepetsa mapindikidwe awo. Izi kumawonjezera permeability Mitsempha, omwe lumen yopapatiza.

Izi zimatha mankhwala kumabweretsa bwino microcirculation, ubwino minofu hypoxia.

Kodi "Pentoxifylline?" Analogues wa inatha ndi Russian chimodzimodzi achire zotsatira monga wa ndalama yokha. Pambuyo ntchito mankhwala, amachepetsa loitanirana wa erythrocytes amene kenako mosavuta kuwonjezera magazi ziwalo ndi kudutsa mu malangizo extravascular.

Sitingathe kunena kuti mankhwala ankaona amachepetsa magazi kukhuthala, motero amalimbikitsa kupatsidwa zinthu za m'mwazi disaggregation. Chifukwa cha zotsatira za mankhwala ndi kuchuluka yokha ndi sitiroko buku, koma sasintha ziwerengero kugunda kwa mtima.

Choncho, chotengera m'mapapo kuwonjezeka bwino O ₂ zili magazi, ndiponso kufala kwa mitsempha inatsekeratu kuonjezera O ₂ yobereka kuti myocardium lapansi.

Ankaona chiphunzitso angathe kuwonjezera kamvekedwe ka minofu kupuma ndi zakulera. Imawalamulira kumaonjezera kuchuluka kwa magazi amene amatuluka kudzera collaterals, komanso kumatheka magazi mwa iwo.

Kodi mbali zina za mankhwala ali "Pentoxifylline?" Analogue za mankhwala ndi mankhwala yokha kuwonjezera ndende ya ATP mu ubongo ndi bwino kusowa magazi kumadera zowonongeka (mwachitsanzo, mu sitiroko ischemic).

Iwo ayenera kukumbukira kuti mankhwala anati kumakhudza zabwino pa dongosolo chapakati mantha ndi ntchito zake. Mu zotupa za mitsempha zotumphukira ntchito izi zikutanthauza kumam'phunzitsa kuonjezera kuyenda mitunda italiitali, kuphatikizapo matenda monga endarteritis obliterative.

magawo pharmacokinetic

mankhwala "Pentoxifylline" Kodi inatenga nthawi yaitali? Malangizo ntchito (analogues wa mankhwalawa m'munsimu) imatiuza kuti mankhwala ali kwambiri ozama mphamvu, kuphatikizapo kupyolera m'mwazi-ubongo chotchinga.

Hafu ya moyo wa mankhwala pamene kutumikiridwa m'nsinga ndi mphindi 30. Pamene kulandira mankhwala mkati kwathunthu odzipereka kwa mundawo m'mimba.

Medicament kusandulika mu chiwindi, kumene ndipamene metabolites theobromine. The pazipita magazi ambiri mankhwala zimatheka mwa maola 4 pambuyo ntchito. Komabe, ikhala pa milingo achire pafupifupi tsiku.

Anasonyeza medicament mu impso (pafupifupi 95%). intestine kudzera mankhwala kunja pang'ono.

Pa kugonana fairer amene kuyamwitsa, mankhwala akhoza kumasulidwa pamodzi ndi mkaka. Iwo ayenera kukumbukira kuti kuwonongedwa kwa mankhwala mochedwa odwala ndi matenda aakulu impso, chiwindi ndi okalamba.

Zikuonetsa ntchito

Chifukwa chanji wodwala akhoza anatumizidwa mankhwala "Pentoxifylline?" Analogs ndipo mmalo mankhwala ndi zizindikiro zofanana.

Panopa, chotero mankhwala ogwira ntchito pofuna kuchiza matenda ambiri. Apa tsopano:

• cerebrovascular akusowa;
• urolithiasis;
• arteriosclerotic encephalopathy;
• ischemic sitiroko;
• ashuga nefroangiopatiya;
• oopsa;
• obstructive matenda;
• bronchial mphumu;
• zotumphukira magazi matenda ;
• encephalopathy;
• algomenorrhea;
• sepsis;
• cholecystitis;
• matumbo dyskinesia ;
• pilorospazm;
• minofu yosalala kuphipha;
• pambuyo trombophlebitic syndrome;
• dysmenorrhea;
• angioneyropatii (matenda Raynaud a) ;
• matenda magazi diso;
• trophic minofu matenda;
• zilonda trophic;
• kuopseza padera;
• matenda zinchito pakati ndi makutu mkati;
• mtima mpheto;
• akulu dystrophy;
• chilonda, frostbite.

contraindications

Amene matenda akuletsedwa ntchito mankhwala "Pentoxifylline?" An analogue a mankhwala ndi mankhwala iyoyomwe siingakhoze kumwedwa kwa anthu ndi tsankho kwa zigawo zikuluzikulu, komanso nthumwi zina za gulu xanthine.

Komanso, mankhwala ankaona contraindicated odwala amene ali posachedwapa anadwala hemorrhagic sitiroko kapena pachimake m'mnyewa wamtima infarction komanso akudwala aakulu atherosclerosis mtima ndi mitsempha ubongo, porphyria.

ntchito mankhwala mtsempha zoletsedwa kwa arrhythmia, magazi, kuthamanga otsika magazi, kukha magazi mu diso. Komanso, mankhwala ali contraindicated pa mkaka wa m'mawere ndi gestation, ana kwa zaka 18.

Ndi wapadera kusamala akapatsidwa limatanthauza anthu opareshoni (pofuna kupewa magazi a nembanemba mucous ndi ziwalo), ndi odwala ndi impso kwambiri ndi chiwindi, intestine matenda chilonda, gastritis ndi matenda a mtima.

Njira Ntchito

Kodi kugwiritsa ntchito mankhwala "Pentoxifylline?" Malangizo ntchito kwenikweni (analogues wa chida zimenezi Mlingo osiyana) anakumana madokotala kuti mankhwala akutengedwa pakamwa ndi parenterally (malingana ndi kuopsa kwa matenda).

Dongosolo Oral mankhwala kuyamba ndi mlingo wa 200 mg (i.e., mapiritsii 2 katatu pa tsiku, pambuyo chakudya). Atafika mwachindunji chiwerengero cha zotsatira achire yafupika ndi theka. The njira ya mankhwala mankhwala ayenera lolimba zosaposa mwezi umodzi.

Matenda aakulu ndi wokonda ziwalo mankhwala kutumikiridwa mu makapisozi. Pali 2 njira zakayendesedwe ka mankhwala: mtsempha ndi intraarterial. Ndondomeko yoyamba anachita ndi dropper a. Chifukwa chaichi, 1 vial 250 ml ya shuga njira kapena sodium kolorayidi. Anati mlingo chikuyendetsedwera pasanathe maola 2.

Koma makonzedwe intraarterial, ndi kutumikiridwa mu mlingo wa 0,1 ga pa 50 ml ya yothetsera sodium kolorayidi.

zotsatira zoyipazi

Mwa mavuto ambiri mbali izi:

• chizungulire, nkhawa, matenda tulo, khunyu, kusintha maganizo, mutu;
• cholecystitis exacerbation, okwera chiwindi transaminases, chitukuko cholestatic chiwindi;
• kusanza, kumverera kwa chidzalo m'mimba, kunyansidwa, kutsekula m'mimba, kusafuna kudya;
• ming'oma, anaphylactic mantha, kuyabwa, angioneurotic edema, redness a khungu;
• pakutchulidwa wa arrhythmias, kupweteka mtima, kuchepa magazi, stenokardicheskie kuwawa;
• thrombocytopenia, leukopenia;
• malawi, kuona;
• exacerbation mphumu, bronchospasm, kupuma insufficiency;
• magazi a etiology osiyana.

Mankhwala "Pentoxifylline": analogues, mtengo

Analogs amaonedwa mankhwala mankhwala zotsatirazi:

• dragees "Agapurin" (100 mg) ndi yankho jekeseni mu ampoules (100 mg);
• miyala "M'phika", mapiritsi TACHIMATA (600 mg);
• dragees, miyala ndi injectable njira "Trental".

Tikumbukenso kuti "Trental" akuimira mankhwala pachiyambi. Iye amagwira ntchito odwala encephalopathy chiyambi osiyana.

Monga mtengo, ndiye kukonzekera onsewa ndi osiyana. Analogue "Trental" "Pentoxifylline" zikhoza kugulidwa kwa 120 rubles medicament choyambirira - chifukwa 520 rubles "Agapurin" - rubles 300, pamene "M'phika" - 400 rubles.

Reviews

Reviews za mankhwala zimagwiritsa positive. Mankhwala ndi othandiza matenda mtima ziwalo zambiri ndipo kachitidwe. ndemanga kwambiri pa ntchito ya "Pentoxifylline" anamuthawa anthu amene akuvutika ndi kuwononga endarteritis ndi claudication likukulira. medicament Ichi ndi chifukwa iwo njira № 1, kuyambira matenda amamuchititsa patsogolo.