Matenda Huntington a - Chobisika ngozi

Medical mabuku kupereka tanthauzo zovuta matenda, amene amatchedwa matenda Huntington a. Pofuna kumvetsa chiyambi ndi makhalidwe a matenda oopsa, m'pofunika kuzindikira zimene aliyense mawuwa amagwiritsidwa ntchito tanthauzo lake.

Matendawa ankaona kuti cholowa, autosomal lalikulu. Izi zikutanthauza kuti matenda ndi majini ndi tinatengera kapena kholo, ndi mmodzi mutated mbewu. The zochitika mwa anyamata ndi atsikana zofanana.

matenda Huntington a - matenda a aakulu pang'onopang'ono. Si ankachitira, akufotokozera pang'onopang'ono, zonse kuwonjezeka zizindikiro zina akusuntha mu gawo pachimake. Matendawa nthawi zonse limodzi ndi matenda okhudza ubongo, matenda extrapyramidal (matenda kayendedwe).

The pathogenesis wachisokonezo wakhala anaphunzira bwino kwambiri. Komabe, amadziwika kuti odwala anthu amakonda kuchepa kwa GABA (asidi aminobutyric, umene uli wofunika kwambiri ochepetsera mtundu) maselo a ubongo. Pakali pano, ku maselo a substantia nigra zambiri kumawonjezera chiwerengero cha chitsulo, pali matenda zakuthwa kagayidwe dopamine. Akatswiri ena amakhulupirira kuti matenda matenda Huntington a amayamba ndi kutalikitsa maunyolo amino zidulo. Choncho apanga "cholakwika" mapuloteni kusokoneza njira amuzolengedwa mu ubongo.

Iwo kukhazikika bwino kuti Mwina ndi mwana ndi matenda jini TV banja kuonongeka ndi 1: 1 kaya kugonana mwanayo.

Zizindikiro za chorea Huntington a

matenda Huntington ndi ambiri amakhala noticeable kwa zaka 30 (nthawi zina pambuyo). Choyamba, pali matenda aluntha: a kuchepetsa wa manyazi, "kupanikizana" pa mfundo imodzi. Anthu kutaya luso kupenda zochitikazo ndi kutengapo maganizo.

Pang'onopang'ono matenda amenewa kukhala mu maganizo patsogolo. Wodwala mofulumira zatha maganizo, nzeru ziwole Mwamsanga zinachitikira. Pang'onopang'ono angaimbidwenso umunthu wa wodwalayo.

Mu yomweyi, osauka matenda hyperkinetic. Odwala ndi matenda a "matenda Huntington a" involuntarily anayamba kupanga kwambiri kayendedwe ochepa kwambiri, motero kutaya mwayi wopezera zochita wophweka. Mwachitsanzo, kuyenda limodzi grimacing m'mwamba manja ndi m. P.

matenda Huntington si chomwecho. Nthawi zina, makamaka mu magawo oyambirira, odwala maganizo kupondereza ngakhale hyperkinesis amphamvu, ndipo nthawi zina zikhoza anasonyeza bwino kwambiri. matenda maganizo nthaŵi zonse, koma mlingo wa ukulu wake angakhale osiyana. Nthawi zina odwala, ngakhale kudzitsitsa osaleka kusunga pakati awo odzikonda ndipo nthawi zina adzautaya mofulumira kwambiri. N'chiyani chathandiza kuti ziwalo, mankhwala sanayambebe anakhazikitsa.

matenda Huntington a. Matendawa ndi mankhwala

Chifukwa matenda, odwala ayenera kukumana akugwirira, Kujambula. Kawirikawiri maphunziro awa anawerengedwa manja a kotekisi oziziritsa ndi kusintha ntchito zake magetsi, pali otchedwa indentation ndi thalamus.

Pakuti mawu a matenda, madokotala anafufuza madzimadzi cerebrospinal, Kuphunzira mbiri ya matenda m'banjamo. Today zambiri anagawira njira preclinical matenda mabanja amene ali mu gulu chiopsezo. Yankholo mu tilinazo lymphocytes kuphunzira X-ray. Ana obadwa m'banja limene pali matenda chonyamulira, ayenera kulembamo zachipatala.

matenda Huntington ndi wosachiritsika. Kuti atsogolere alili awerenge maofesi a triftazine, reserpine ndi muzikangana ena dopamine ndi asamakhale ndi nkhawa.