Popanga madzi a gamma-aminobutyric acid. Zizindikiro za akusowa mu thupi

Mtsogoleri chachikulu cha thupi lathu - ndi ubongo. Uyamiko kwa Iye, mgwirizano kanthu ndi machitidwe onse. ife tithe kusuntha, onani, kumva, kulankhula, kumva ndi kudziwa Mothandizidwa ndi ubongo ndi msana. Mwachibadwa, chapakati ndi zotumphukira machitidwe mantha kunyamula zochita zawo kudzera mwa nyumba wapadera - timene. Zikuphatikizapo angapo zinthu kuthandiza ubongo kusonyeza.

Zimene timene thupi

Kuti akachite HIV pakati pa ulusi mitsempha, komanso minofu minofu zofunika othandizira. Iwo ali nkhoswe, amene akuchititsa kugunda magetsi kudutsa danga synaptic. The nyemba ndi pa mathero mitsempha ndipo asanafike mapeto, amachititsa kutuluka kwa mtundu. "Athandizi" amagwa kusiyana ndi zimakhudza ndi minyewa wapafupi amene akukhala permeable kwa chizindikiro. Choncho imafalikira nyemba zonse magetsi mu thupi. Timene - chinthu chiyambi mankhwala, zomwe zingachititse onse malemeredwe ndi chopinga mu chapakati mantha dongosolo. Iwo agawidwa m'magulu 3: amino zidulo, mapeputisayidi ndi makatekolamaini. Oimira ambiri ali Epinephrine ndi norepinephrine, Popanga madzi a gamma-aminobutyric asidi, glycine, dopamine, serotonin, glutamate, acetylcholine.

ntchito GABA mu thupi

Popanga madzi a gamma-aminobutyric asidi (English GABA) anafotokoza kuti owayimira kuti ziletsa wamanjenje dongosolo. Ndi mankhwala mankhwala alipo anthu ndi nyama. GABA ndi imodzi zidulo zofunika kwa amino, amene sangathe lithe zedi. Ngakhale izi, kufunika kwake mu thupi ndi lalikulu kwambiri. asidi Popanga madzi a gamma-aminobutyric amagwira ntchito ziwiri zofunika:

1. Mtundu kanthu. Chifukwa zotsatira zake ochepetsera wa GABA ali hypotensive, sedative, zotsatira anticonvulsant. Komanso, kumathandiza kuti kukondoweza tulo, nthawi galimoto ntchito bwino njira yokumbukira ndi maganizo.
2. Kagayidwe kachakudya ntchito. GABA bwino njira kagayidwe kachakudya mu ubongo ndi magazi, maselo mitsempha limapereka mphamvu. Ndiyamika mankhwala ikuchitika Mwa zina zikuluzikulu - odana hypoxic, mwachitsanzo kupeŵa mpweya njala. Kenako zochita za GABA - kuchotsa mankhwala kagayidwe kachakudya ku thupi ndi mmene kukondoweza kwa kupanga kukula timadzi ndi pituitary zapambuyo.

Magwero a asidi Popanga madzi a gamma-aminobutyric

GABA ndi chimodzi mwa zigawo za magazi ndi ubongo minofu. Ndi wopanda nkhokwe zachilengedwe m'pofunika kupeza izo ndi zinthu zina. Popanga madzi a gamma-aminobutyric asidi alipo mankhwala ena zomera. Zikuphatikizapo tiyi ndi khofi masamba, bowa filamentous, komanso madzi mtundu wa zomera cruciferous. Komanso, GABA zakonzedwa kudzera mankhwala pogwiritsa ntchito njira microbiological. Pakuti chitukuko ntchito mabakiteriya anthu monga E. coli. Mu mankhwala muli mankhwala zofunika - nicotinoyl Popanga madzi a gamma-aminobutyric acid. Zimatanthauza analogs akamagwira zasayansi.

Zizindikiro za akusowa GABA mu thupi

Pa kusowa kwa asidi Popanga madzi a gamma-aminobutyric, nambala njira pathological. The akuluakulu ali - omangana maganizo, nkhawa, ndi minofu. Iwo amagwirizana ndi ntchito yafupika anachita mu thupi la asidi Popanga madzi a gamma-aminobutyric. GABA pakufunika kupereka ubongo ndi mphamvu, kulamulira njira zikuchitika mu izo. Choncho, pamene akusowa ake akufotokozera CNS matenda ambiri. Njirazi ndi monga:

1. Cerebrovascular matenda - matenda oopsa, atherosclerosis, sitiroko ndi mtima kuukira.
2. Mutu, kufooka, chizungulire, tulo zipolowe, kukumbukira, chidwi.
3. Khunyu.
4. matenda a Alzheimer.
5. Oziziritsa ziwalo.
6. Encephalopathy.
7. Kuwonjezeka mlingo wa kukula timadzi.
8. Maganizo ndi choipa ubongo.
9. Parkinson matenda.
10. Maganizo limati.
11. Hypoplasia njira maganizo ana.
12. Silifuna mantha ndi maganizo udindo.
13. Nyanja ndi matenda mpweya.

Zonse zizichitika amafuna mankhwala kudzazidwa Popanga madzi a gamma-aminobutyric asidi, komanso kuchuluka ntchito mankhwala umene uli.

Mankhwala okhala GABA

Pofuna kuthetsa kupanda asidi Popanga madzi a gamma-aminobutyric, pitani kuchipatala. Iye adzaika chokwanira m'malo mankhwala. Thunthu yaikulu ya mankhwala - ndi Popanga madzi a gamma-aminobutyric acid. Analogs muli zina mwa mawonekedwe a calcium, nicotinoyl, ndipo opangidwa kuchokera kwa GABA. mankhwala waukulu ndi mankhwala "Aminalon", "Pikamilon", "Phenibut", "Neyrobutal", "a GABA". Zikuonetsa ntchito zonse za mankhwala awa ndi matenda chifukwa cha kusowa kwa asidi Popanga madzi a gamma-aminobutyric mu thupi. Medicaments munali GABA contraindicated ana pansi 1 chaka cha amayi apakati (mu trimester), hypersensitivity kuti zinthu zazikulu kapena wothandiza ndi pachimake kulephera aimpso.

Popanga madzi a gamma-aminobutyric asidi: umboni

Poika GABA kapena analogues zake odwala kwambiri kuchuluka kwa dzuwa, kugona ndi maso lamulo, pali kukumbukira kusintha ndi kuchepetsa limati maganizo atazikocheza kupweteka. Mwa mavuto ena odwala lipoti dyspepsia, kuchuluka libido, kusinza.