Houtington's chorea: kufotokoza za matenda

Huntington Huntington ndi matenda osatha omwe amapita patsogolo ndi matenda ozunguza matenda omwe amaphatikizidwa ndi matenda ndi maganizo ndi magalimoto. Chomwe chimayambitsa kukula kwa matenda ndi chibadwa chosawonongeka, chomwe chimapangitsa maonekedwe a mitsempha ya mitsempha yomwe imatha kusokoneza maselo osagwira mtima omwe amachititsa kuti thupi likhale lopanda mphamvu komanso zimayambitsa zochitika za ubongo. Patapita nthaŵi, matendawa amakula, ndipo zizindikiro zake zimakhala zolemetsa.

Pamene matendawa mu maselo a ubongo akuphatikiza kuchuluka kwa gamma-aminobutyric asidi, ndipo m'maselo a mitsempha ya chigaza imachulukitsa kuchuluka kwa chitsulo ndi kusokoneza kusinthanitsa kwa dopamine.

Matenda a Huntington amafalitsidwa kuchokera kwa kholo lodwala lomwe limanyamula zamoyo zosawerengeka, malinga ndi mtundu wa autosomal. Ngati matenda a mmodzi wa makolo a chorea, chiopsezo cha kuwonetsa kwa mwanayo ndi makumi asanu. Zizindikiro zoyamba za matendawa zimawoneka ali ndi zaka 30 mpaka 40.

Matendawa amapezeka m'milandu 3-7 pa anthu zana limodzi mwa anthu a ku Ulaya, pakati pa anthu amodzi mwa milioni ali odwala.

Huntington wa chorea: zizindikiro

Kumayambiriro kwa matendawa pali khalidwe la chorea hyperkinesis, zosasintha, zofulumira, zosasunthika. Ngati panthawi yoyamba, odwala amatha kuthetsa machitidwewa ndi mphamvu, ndiye kuti matendawa amayamba, mphamvuyi imafooka. Matenda osagwirizana ndi matenda ndi matenda amayamba kawirikawiri pakatha nthawi inayake chiyambireni matendawa.

Pamene munthu ali ndi matenda, nzeru zimachepa ndipo chifukwatu chimayamba.

Pakupita patsogolo kwa matendawa, odwala amakumana ndi mavuto akuluakulu ngati akufuna kuchitapo kanthu. Mwachitsanzo, pakuyenda, munthu amachita manja osayenera, amapanga masewera, grimaces, amazembera pamene akusunthira. Kwa odwala, kulankhula kumakhala kovuta, kuchepa kwa minofu kumachepa, ndipo dementia imayamba pang'onopang'ono. Munthu sangathe kukhala wotanganidwa kwa nthawi yaitali (kutseka chibonga chake, kukonza maso ake pa chinthucho).

Matenda otchedwa endocrine ndi matenda a neurotrophic angayambe.

Chorea Huntington: Kuzindikira

Kusanthula kumachokera ku zizindikiro za kuchipatala komanso mbiri ya banja. Pochita kafukufuku, kusintha kwakukulu ndi kusintha kwa ubongo wa mutu kumatsimikiziridwa. Mukapezeka, chorea imasiyanitsidwa ndi Alzheimers, Parkinson's, syphilis, encephalitis, ziphuphu za ubongo zomwe ziri ndi zizindikiro zofanana.

Chorea Huntington: mankhwala

Masiku ano, palibe njira zothandizira matenda omwe akanalola kuthetseratu mawonetseredwe onse a matenda a Huntington kapena kusiya chitukuko chake. Nthaŵi zambiri, mankhwala opatsirana amachititsa. Kuti athetse hyperkinesis, odwala amatenga mankhwala apadera.

Pamene kupweteka kumachitika, matenda opatsirana maganizo ndi matenda opatsirana amaperekedwa. Kuti athetse vuto la odwala limapereka mankhwala oletsa antipsychotic (antipsychotics), otetezera, sympathomimetics, anti-depressants.

Matendawa ndi ovuta ndi mawonetseredwe opatsirana, chifuwa chibayo chikhoza kuchitika .

Kawirikawiri kuyembekezera kwa moyo wa anthu omwe akudwala matendawa ndi zaka 15 mutapezeka zizindikiro zoyamba za matenda. Kawirikawiri, ndi chitukuko cha zizindikiro zoyambirira pa msinkhu wawo, matendawa amakula mofulumira. Kotero, ngati kwa nthawi yoyamba zizindikiro za matendawa zimapezeka kwa odwala osapitirira zaka 20, kuyembekezera moyo wawo sikudutsa zaka zisanu ndi zitatu. Nthawi zambiri, imfa imachokera ku mavuto omwe amachititsa kuti munthu asamangodziwa. Achisanu mwa odwala amadzipha.