Hemolytic magazi m'thupi-Chauffard Minkowski: matenda ndi mankhwala

Mu magazi m'thupi, mlingo magazi hemoglobin akutsikira zikuchepa. Ndi matenda pamoyo wawo nawo anthu ambiri. Komanso, sikuti kupewa mbali ngakhale ana aang'ono. mitundu kwambiri matendawa amayambika ndi zakudya osauka, kupanda mavitamini, kapena mukumwa mankhwala. Pambuyo pothetsa zizindikiro zonse n'zothandiza chinthu cropped. Pakati zosiyanasiyana njira pathological allocated zovuta ndi zoopsa kwambiri. Izi hemolytic magazi m'thupi-Chauffard Minkowski. Ndicho za izo m'nkhani lero.

magazi ndi chiyani?

Pansi magazi ambiri amadziwira monga boma la thupi, yodziwika ndi lakuthwa zizindikiro kuchepa kwa maselo ofiira a magazi ndi hemoglobin. Ena mitundu ya matenda kumabweretsa kusintha mawonekedwe maselo a magazi. Kusiya ntchito yawo yaikulu pa nthawi.

Magazi nthawi zambiri limodzi ndi zosiyanasiyana matenda, koma osati yaikulu. N'chifukwa chake sitiyenera kuchoka popanda vutoli. M'pofunika posachedwapa kupeza chifukwa ndi kuyesa kuthetsa.

NKHANI hemolytic magazi m'thupi

Mawu akuti "hemolytic magazi m'thupi" zikuphatikizapo gulu lonse la matenda. Onse yodziwika ndi pathogenesis wamba. Kuchuluka kuwonongedwa kwa maselo ofiira amachititsa kuwonjezeka mu malonda awo kuwonongeka ndi kuwonjezeka mu erythropoiesis. Kuzungulira mapangidwe ndi akusokoneza maselo ofiira. Njira chiwonongeko chawo pang'onopang'ono kuyambira kupambana pa njira ya zikamera ndi kusasitsa.

Onse magazi m'thupi haemolytic salembedwa m'magulu awiri: cholowa ndi zinazake. M'nkhaniyi, tili tione mwatsatanetsatane pa buku loyamba. Kukhala enieni, timaona kuti ndi cholowa magazi m'thupi-Chauffard Minkowski.

Mu mabuku mankhwala Buku mungapeze maina angapo ofotokoza za ndondomeko pathological. Izi magazi m'thupi microspherocytic ndi cholowa spherocytosis, ndi matenda Chauffard Minkowski. Nthawi zambiri ntchito dzina lotsiriza ndi mayina asayansi, otulukira.

Matendawa imatengedwa kuti ndi ofala kwambiri (1 uliwonse Population 5 zikwi.). Iwo matenda makamaka anthu a Kumpoto kwa Ulaya. Zizindikiro zoyambirira zimaonekera mwa ana aang'ono. Ngati mulibe kuyamba kuchiza matenda m'njira yake chifukwa amadza chifukwa cha zoipa kugwira ntchito kwa chamoyo wonse.

Zimayambitsa ndi njira ya matenda

Magazi m'thupi Minkowski-Chauffard limodzi ndi chisokonezo cha nembanemba ma nyumba erythrocytes ndi ntchito. The chifukwa cha njira izi amasintha mawonekedwe awo ndi zozungulira, kukhala Chimaona. Zizindikiro zoyambirira za hemolysis - kuwonongedwa maselo a magazi ndi munthawi yomweyo amasulidwe hemoglobin.

Mu wathanzi anthu maselo a magazi mawonekedwe awo amatikumbutsa chimbale biconcave, kotero kuti iwo kusuntha momasuka kudzera ziwiya. Mu magazi m'thupi, zinthu nembanemba wa kaphatikizidwe mapuloteni anawawidwa. Zimenezi zimabweretsa malowedwe zakumwa mu maselo. Chifukwa cha ichi, iwo amasintha mawonekedwe awo. Kudutsa ziwiya magazi, maselo ofiira akudwala opunduka, ndipo patapita kanthawi zimasiya kugwira. Against maziko a ndondomeko yopitilira, mlingo wa maselo ofiira akutsikira kwambiri, kukhala hemolytic magazi m'thupi.

Ngati kholo limodzi ali kale ndi matenda awa, izo kwenikweni akamadutsa cholowa mwana. kawirikawiri ana odwala amabadwa Moms mwangwiro wathanzi ndi osasamala. Pankhaniyi, magazi m'thupi akufotokozera ndi maziko a kusintha DNA lapansi. Jini kusintha chachikulu kumachitika ngakhale pa chitukuko yoopsa. Chofunika chitukuko cha matenda ndi yaikulu thupi la mayi zinthu zotsatirazi:

• cheza, X-ray;
• kuledzera ndi katundu zitsulo salt, mankhwala osokoneza bongo, chikonga;
• HIV kuukira.

Mchikakamizo cha zimenezi mulole osati magazi m'thupi-Chauffard Minkowski, komanso kudwala yaikulu kwambiri. Choncho, pa mimba, mkazi ayenera kuyesetsa kuteteza thupi lanu.

Zizindikiro zoyambirira

Chithunzi matenda makamaka anatsimikiza ndi kuopsa kwa ndondomeko pathological ndi kuchuluka kwa erythrocytes kusinthidwa. zizindikiro poyamba zingaoneke ana a sukulu ndi zaka sukulu oyambirira. Pa mtundu wa magazi m'thupi zambiri undulating. Khunyu hemolytic mavuto pamene pali ambiri chiwonongeko munthawi yomweyo maselo a magazi, kenako nthawi ya chete. Pankhaniyi, zizindikiro zingasiyane pang'ono.

Mwachitsanzo, interictal nthawi ya matenda akuwonetseredwa zizindikiro za kuchepa kwa magazi m'thupi. Ena mwa iwo ndi pallor a khungu, zikopa mucous kapena maso. Ngati hemolytic mavuto matenda chithunzi akasintha ndi limodzi mwa zizindikiro zotsatirazi:

1. Kuwonjezeka kutentha kwa madigiri 38, mutu, malaise.
2. Chitukuko cha matenda a chikasu ndiyo.
3. Kupweteka pamimba, yodziwika khalidwe chonsechi.
4. Kusapeza mu chiwindi chifukwa kuchuluka kwake.
5. Kutupa ndulu ya.

Cholowa hemolytic magazi m'thupi-Chauffard Minkowski anapeza akuluakulu. Chifukwa zambiri pofuna funa chithandizo cha mankhwala mu nkhani iyi ndi yellowness wa khungu. Komabe, nthawi zambiri, matenda ndi asymptomatic. Odwala kuphunzira linakhalapo mwangozi ndipo kawirikawiri pamene kuyendera chizolowezi.

Kupenda Medical

Matenda a magazi m'thupi-Chauffard Minkowski ndi wosavuta. Ngati mukukayikira matenda, ndipo zikuoneka zizindikiro koyamba ayenera pitani kuchipatala. Kudwala a dongosolo hematopoietic ali mu yamtunduwu wa panthawiyi, dokotala wina. Atafufuza madandaulo a wodwalayo komanso wake katswiri mbiri banja ayenera kuyendera khungu ndi sclera, kuchititsa palpation m'mimba. Mokakamizidwa anatumizidwa ultrasonography a chiwindi ndi ndulu, monga chizindikiro cha matenda ndi kuwonjezeka mu kukula kwa matupi awa.

Imodzi panthawiyi, dokotala amapereka malangizo kwa anthu mayesero zasayansi. Hemolytic magazi m'thupi-Chauffard Minkowski anatsimikizira pamaso pa kusintha zotsatirazi:

1. Mkodzo: hemoglobinuria, kuchuluka zizindikiro mapuloteni ndi urobilin.
2. Sayansi magazi: kuchepetsa mafuta m'thupi, lactate dehydrogenase, kukula, kuwonjezeka bilirubin zina.
3. Kafukufuku maselo a magazi: reticulocytosis kutchulidwa, kuchepetsa kukula selo, kuchepetsa bata awo osmotic.
4. General kusanthula magazi: ESR mathamangitsidwe, kuchepa pang'ono kupatsidwa zinthu za m'mwazi ndi kuchepetsa leukocyte mtundu chizindikiro.

Pomaliza kutsimikizira mapeto kuyambirira amathandiza khalidwe electrophoresis mapulotini wa erythrocyte Kakhungu molumikizana ndi quantitation awo.

matenda masiyanidwe

Hemolytic magazi m'thupi Minkowski-Chauffard ana amayambitsa mavuto pa matenda. matenda Izi zikufanana ndi zizindikiro zina autoimmune pathologies. Choncho, madokotala ayenera kudziwa zina lenileni ndi khalidwe mtundu wa zizindikiro magazi m'thupi.

Choyamba tikulankhula ndi kutengera za kumtundu. Pokha pokha kwapadera makolo onse ali wathanzi kwathunthu. Komano, ndi mwana wodwala unkagwiritsidwa kusintha osiyana mu mafupa a Chigaza lapansi. Nthawi wofooka Komanso anatumizidwa Coombs nyemba. Ngati kusanthula ndi zoipa, wodwalayo imayendetsedwa magazi m'thupi-Chauffard Minkowski. Matendawa ali ukakhale anamaliza.

chithandizo ndiwofatsa

Magazi m'thupi mankhwala anasankhidwa chifukwa cha ukulu wake. Pa tizigona, monga ulamuliro, alowererepo chofunika. Pa kuukira lotsatira wodwalayo kuchipatala mwamsanga.

chithandizo ndiwofatsa wa magazi-Chauffard Minkowski zikuphatikizapo miyezo zotsatirazi:

1. M'malo mankhwala erythrocyte misa, ngati mlingo magazi hemoglobin akutsikira mlingo wa 70 g / L.
2. Albumin akusonyeza mankhwala ziwawa za bilirubin.
3. Pakuti detoxification ntchito kulowetsedwa mankhwala.
4. Popeza lofotokoza mavuto hemolytic chikusonyeza phwando mankhwala choleretic.

Kutalika kwa mankhwala amenewa, mankhwala enieni ndi mlingo awo - mavuto onsewa ali anaganiza ndi dokotala pa paokhapaokha.

ntchito alowererepo

Ngati microspherocytic hemolytic magazi m'thupi-Chauffard Minkowski kwambiri, mankhwala ndiwofatsa sangathe kulimbana ndi zolinga anati, wodwalayo akulangizidwa opaleshoni kuti achotse ndulu. Chotero njira simungathe kwathunthu kuchiza matendawo. Komano, pambuyo alowererepo chiwerengero cha kuwonongedwa maselo ofiira kwambiri yafupika ndi lengthened mkombero moyo wawo.

Hemolytic mavuto pambuyo ntchito si mobwerezabwereza, koma zingapo contraindications. Mwachitsanzo, kuchotsa ndulu ali osavomerezeka chifukwa ana osaposa zaka 5 chifukwa cha ziwawa imfa mu nthawi postoperative. The downside wochita imatengedwa kuti ndichepe kukaniza thupi ndi ulemu matenda tizilombo ndi mafangasi.

An chimake zina amaona kuchotsa ndulu endovascular occlusion. Iyi ndiyo njira ina mankhwala kuthandiza kawirikawiri anafuna mu matenda a "microspherocytic magazi m'thupi-Chauffard Minkowski." Pa ndondomeko, dokotala amaika mu thupi la mankhwala amakwiya spasms, ndi ndulu kumayambitsa matenda a mtima. Zina mwa izo ndiye amapulumutsa zonse kotunga magazi ndipo sasiya luso kulimbana ndi matenda.

zosokonezeka zotheka

Hemolytic magazi m'thupi-Chauffard Minkowski sukulu ana nthawi zambiri kumayambitsa kuchedwa mu chitukuko maganizo ndi thupi. Makamaka ngati makolo kwa nthawi yaitali sanafune kuchipatala kapena malangizo ananyalanyaza dokotala.

Odwala wamkulu, ndi Vuto ambiri amaona ndi maziko a matenda matenda gallstone a kagayidwe bilirubin. Chinthu ndi mavuto hemolytic zimachitika monga chiyambi cha chitukuko cha matenda a chikasu ndiyo, kotero mankhwalawa anachedwa. Pamaso pa miyala ndulu ya tikulimbikitsidwa kuti cholecystectomy ndi splenectomy.

The Mapa apeze

Mu matenda zochepa kwambiri ndi khalidwe yake ya opaleshoni kuchotsa ndulu yabwino madokotala ananena zawo. Chikhululukiro zambiri kukuwonekera mwamsanga mavuto hemolytic. anakhala zosiyanasiyana, koma nthawi zambiri ndi zaka ziwiri.

njira kuteteza

Magazi m'thupi Minkowski-Chauffard ndi cholowa. Choncho kuteteza zosayembekezereka wa matenda sizingatheke. Pofuna kuteteza mitundu choopsa cha matenda odwala matenda ndi mawonekedwe a magazi m'thupi Ndi bwino kuti nthawi kukumana anayendera wathunthu panthawiyi, dokotala wina.

Pamene akukonzekera kukhala ndi pakati ayenera kumvetsa kuti imabwera kudwala matenda a mwana wosabadwayo ndi 50%. Choncho atabadwa limasonyezanso polojekiti mosalekeza ndi dokotala kudziwa pathologies pa siteji oyambirira.