Porphyria - matenda a anthu amakono

matenda porphyria ndi wapadera pathologies chiwindi pa mlingo chibadwa, mmene muli pachithunzichi mwamtheradi hemoglobin kaphatikizidwe. Amakhulupirira kuti pali eyiti motsatizana otchedwa masitepe enzymatic mu biosynthesis wa hemoglobin. aliyense wophwanya pa siteji ya mmodzi wa iwo kale kuyambitsa vuto monga porphyria. Matendawa zambiri akufotokozera mofulumira. M'nkhani ino tikambirana mwatsatanetsatane kwambiri kuti ndi matenda ndipo kodi njira zamakono mankhwala.

Porphyria - matenda a anthu amakono. ndi limagwirira matenda chiyani?

Poyamba, sanali mapuloteni mbali ya hemoglobin (ayi - heme) ndi n'kukhala chinthu poizoni zimene pamapeto, zonse kudya kutali mwamtheradi minofu onse subcutaneous. Choncho, khungu pang'onopang'ono amapeza ndi kulocha brownish, kukhala n'kakang'ono ndi nthawi, ndi ku Kasupe mwachindunji dzuwa. N'chifukwa chake odwala matenda, mungapeze zironda zambiri ndi zipsera. Pang'onopang'ono osauka porphyria. Matenda, tiona pakalibe chithandizo yake, kawirikawiri likuthandiza m'madera onse atsopano a khungu.

zifukwa

Yotsatana kuphwanya heme biosynthesis, zomwe mwakambirana penapake pamwamba, kumabweretsa kudzikundikira kwambiri a porphyrins mu chamoyo, komanso wotchedwa precursors (mwachitsanzo, Ala ndi porphobilinogen). Zinali zotsala otsiriza ali amphamvu poizoni zotsatira pa chamoyo, chifukwa za zomwe kale osauka zizindikiro matenda. Chifukwa chophwanya amenewa ndi kusintha kwa jini udindo ntchito za michere zina nawo mfundo Mipikisano kaphatikizidwe heme. Pa nthawi, asayansi zikugwira kuphunzira zambiri za njira izi ndi matenda monga porphyria.

zizindikiro matenda

• Kuwonongeka kwa chapakati mantha dongosolo.
• Mkodzo ndi pinkish hue.
• zilonda ambiri ndi mabala pa thupi.
• Ululu ndi kusapeza m'dera m'mimba.
• Kuthamanga magazi.

Kodi tiyenera kuwaona motani?

Mwatsoka, pa mphindi, akatswiri akhoza kupereka njira zothandiza mankhwala pathogenetic za matenda. Nthawi zina (mwachitsanzo, erythropoietic uroporfiriya) mankhwala ntchito. Likukulira porphyria (a matenda siteji pachimake) mwamtheradi salola ntchito dipyrone ndi asamakhale ndi nkhawa, monga iwo chifukwa exacerbation zizindikiro. Pamaso pa ululu matenda monga porphyria, monga ulamuliro, limatchula mankhwala amphamvu.

Pomaliza

Porphyria matenda (chithunzi nambala 1 limasonyeza wina maonekedwe ake), mwatsoka amawapeza m'masiku awa zambiri. Pomaliza, tisaiwale kuti lero mtundu uwu matenda Zatsala bwino kudziwika. Asayansi padziko lonse kupitiriza kufufuza zimayambitsa, zizindikiro chachikulu matenda, komanso njira kulimbana ngati vuto zosasangalatsa. Khalani wathanzi!