LDH - ndichiyani? Zifukwa kuwonjezeka LDH

mankhwala amakono alibe kuima, ndipo tsiku lililonse chikukulirakulirabe. ndi kuchuluka kwa kafukufuku ntchito oterewa matenda osiyanasiyana. Anthu ambiri zimakhala zovuta kumvetsa onse mayina awo. Mwachitsanzo, LDH. Kodi iwo, munthu aliyense mu msewu sakudziwa, koma njira ya kafukufuku, madokotala amagwiritsa ntchito kawirikawiri zokwanira. Kodi matenda apezeke ntchito kusanthula LDH kuposa loyang'anizana kochulukira kapena utachepa mlingo mu magazi. Tiyeni tifufuze.

LDH Kodi

Choyamba tiyenera kudziwa zobisika pansi wachilendo, pa Koyamba, ndi acronym LDH. Lactate - ndi puloteni wapadera, zomwe ndi njira yofunika ya makutidwe ndi okosijeni a shuga ndi kupanga asidi lactic. thupi wamkulu wa mankhwala sangathe kudziunjikira. Chifukwa kusintha kwa zinthu zachilengedwe, akuwonongedwa ndi excreted. Komabe, pali matenda ena kuti yodziwika ndi milingo apamwamba LDH m'magazi. Izi zimachitika pa nthawi imene zowonongeka minofu kapena maselo mthupi. N'chifukwa chake LDH - pentopeni zofunika kwambiri ndi zomwe achitezo diagnostics.

mitundu ya LDH

Chimene icho chiri, ife tadutsa kale asanaganize, koma kufunika kufotokozera ena za maonekedwe a enzyme izi. Monga inu mukudziwa, iye ali ndi mitundu isanu ija, imene amasiyana mzake kokha mwa dongosolo cha ndende. Komanso, aliyense wa mitundu ndi anaikira mu matupi osiyana.

Kusinthidwa wa enzyme yotchedwa lactate dehydrogenase isoenzymes. Choncho, amadziŵika:

• LDH 1 - osakhala mu minofu ubongo ndi minofu mtima.
• LDH 2 - muli maselo magazi (erythrocytes, maselo othandiza magazi kuundana), ndi chiwindi.
• LDH 3 - ali minofu chigoba mu kapamba ndi chithokomiro zopangitsa, komanso zimakhala ziwalo monga mapapo, ndulu ndi zopangitsa adrenal.
• LDH 4 - chimaposa ziwalo chimodzimodzi ndi LDH 3, kuwonjezera, maselo wamwamuna nyongolosi, nsengwa, chiwindi, ndi granulocytes.
• LDG 5 - kwambiri isoenzyme opezeka mu zimakhala minofu chigoba ndi chiwindi, koma ena kuposa icho, alipo ziwalo zofanana ndi LDH 4.

wakudziko

Choncho, tidadzatulukira zimene LDH. Ponseponse wa puloteni imeneyi ndi osiyana akuluakulu ndi ana komanso amuna ndi akazi. Choyamba, zomwe zizindikiro amaonedwa zachilendo kwa ana.

• Pa tsiku loyamba la enzyme ndende moyo akhale 22,1 mkkat / l.
• Masiku anayi izo limatuluka kwa mlingo wa 28,9.
• Kuyambira mlungu miyezi sikisi ndipo anatsitsanso LDH. Voterani ndi 16,3 mkkat / l.
• Miyezi 6 muyezo wa ukuwonjezeka moyo pang'ono kachiwiri, nthawi imeneyi ndi chizindikiro cha 18,3.
• Pambuyo popereka chaka chimodzi mpaka zaka zitatu LDH ana ayenera kukhala 14,2 mkkat / l.
• Kuyambira ndili ndi zaka akalozera seveni amuna ndi akazi osiyana anayamba amasiyana. Anyamata msinkhu ndi zabwinobwino akhale 12,7 mkkat / l, ndi atsikana - 9,67.
• Patatha zaka khumi ndi zitatu za chizindikiro enzyme ndi wolimba pa mlingo wa 11,4 anyamata ndi amuna achikulire. mlingo izi yafupika, ndi moyo ndi 7,27 mkkat / L atsikana ndi azimayi.

LDH magazi. Ndi chiyani icho?

Monga tanenera kale, ndi chikhomo chabwino kwa matenda a mavuto osiyanasiyana m'thupi. Koma zimene tingachite kusanthula amuzolengedwa wa LDH? Njira imeneyi kuyezetsa magazi, mungathe kudziwa kuchuluka kwa lactate m'magazi. Pamene pali kufunika ngati kusanthula ndi?

zikuonetsa kuti

LDH ikuchitika choncho kumene kukayikirana kuti ziwalo anavulala kapena kachitidwe kawo. Iwo minofu choipa amakwiya kuukitsidwa kwa enzyme m'magazi. Zimenezi ndi zoona makamaka kwa mtima minofu, ubongo, m'mapapo, impso, minofu chigoba.

Ngati mukukayikira kuti khansa komanso kuchititsa magazi lactate dehydrogenase. Kodi zikutanthauza chiyani? chakuti kusanthula cimaonetsa metastasis mu ziwalo ndi lymph mfundo. Izi maphunziro njira mu khansa sitinganene kuti ndi zenizeni, koma amalola kuti aziona udindo wa wodwalayo mu nthawi postoperative, ndi kudziwa siteji ya chitukuko chotupa. Komanso pa nkhani ya wogwira mtima amachepetsa enzyme mankhwala magazi Choncho, chikhomo ntchito kuzindikira mphamvu ya mankhwala.

Kukonzekera yobereka kusanthula

Pamaso wozengereza kuwunika, wodwala ayenera kukhala okonzekera izo. Ambiri mwina, dokotala kwanu kulangiza kupewa kumwa mankhwala ena, monga zikukhudzira lolondola zotsatira LDH. Kodi izo, ife waonetsedwa kale. Koma kodi tingatani kumwedwa kwa masiku atatu pamaso kuwunika? Zikuphatikizapo aspirin dzanzi, ascorbic asidi (vitamini C), mitromitsin, clofibrate, procainamide, fluorides. Muyeneranso musiye mowa, chifukwa angadwale mlingo wa enzyme kuphunzira.

Monga kuwunika

Magazi zitsanzo zosankhidwazi zinachitikadi mu mitsempha wamkulu pa mikono khola kudzera singano wapadera. Pofuna mfundo za ana kapena ana, ntchito Lancet. Kuwonjezera mitsempha, adokotala akhoza kutenga magazi kuchokera khutu, pachala chachikulu kapena chidendene. Ikani mpanda kukonzedwa ndi pambuyo ndondomeko amanena kufinya bandeji. Potsatira ndondomeko kumachitika ululu zazing'ono.

zitsanzo magazi anaikidwa mayeso chubu kapena pa maso Wopanda. Zasayansi, ulusi timatumiza kukhala centrifuge wapadera, amene seramu ndi allocated therefrom. Motero, kudziwa mlingo wa enzyme m'magazi.

Zimene ayenera zofunika zimene tanena kale. Kuchuluka kwa enzyme akhoza onse chinawonjezeka ndi kuchepetsedwa. Kodi oyanjidwa?

Chifukwa mlingo kuchuluka kwa LDH

Ngati zotsatira amasonyeza kuwonjezeka LDH, m'pofunika kufunafuna chifukwa cha zodabwitsazi. The mkulu mlingo wa ake ananena kuti panali kuwonongeka kwa minofu iliyonse. Ngati zotsatira kusonyeza kuwonjezeka mu kuchuluka kwa isozyme oposa zambiri, kungasonyeze kuti pali matenda m'thupi. Zimachitika kuti zotsatira zimenezi zikusonyeza kuchuluka mlingo wa mitundu isanu LDH. Pankhaniyi tinganene angapo kulephera limba.

Komabe, matenda sangathe adzaikidwa, chokhazikika pa mlingo wa LDH. A magazi kuti kusintha mu chiwerengero cha isoenzymes amathandiza, kani, mu powunikira wake. Ngakhale akatswiri amafunika kudziwa zomwe akuluakulu kulabadira mu malo oyamba, ngati kukwezeka LDH. zifukwa motere:

• Sitiroko.
• M'mnyewa wamtima infarction. Pankhaniyi, mlingo kukwera kwa maola 36-55 pambuyo nkhondo. An kuchuluka kuchuluka kwa enzyme ukhale kwa masiku 3-10.
• M'mapapo mwanga infarction. zizindikiro choyamba - ululu m'dera pachifuwa. Ndiye, ndipo anakweza kaperekedwe ka enzyme ndi.
• matumbo infarction.
• M'mnyewa wamtima impso, pyelonephritis.
• Congestive mtima kulephera.
• Chiwindi kudwala komanso kukhala chifukwa cha kuchuluka mlingo wa LDH. Kodi zikutanthauza chiyani? Kwenikweni kuchuluka kwa enzyme ichi kumawonjezera ndi kusintha matenda enaake, minofu chifukwa uchidakwa, komanso chiwindi pachimake tizilombo.
• Khansa amagwiritsidwa limodzi ndi kuwonjezeka mlingo LDH.
• matenda magazi imfayo hemolysis.
• LDH ndi chikhomo ndi kapamba pachimake.
• Hypoxia, hypothermia, hyperthermia.
• Lymphoma.
• Mononucleosis, kumene chifukwa cha matenda.
• Atamwa matenda oumitsa khosi. Kuwonjezeka mlingo wa LDH akusonyeza kuti pali encephalitis chitukuko.
• Dystrophy, minofu ya manja, kuvulala awo.
• Mantha mantha.
• Ming'alu ndi fractures.
• amayaka angapo.
• Khunyu.
• Mowa kapena chomwa mankhwalawa kuona zilubwelubwe.
• Eclampsia.
• Kwa amayi ena pakati, milingo apamwamba LDH - boma yachibadwa. Kwa ena, kusanthula zimenezi kungasonyeze detachment wa latuluka lapansi. Mulimonsemo, kuwonjezera mlingo wa LDH - chifukwa kuwona dotolo.

Monga tanenera kale, mlingo apamwamba isoenzymes chimodzi kapena zingapo LDH simungathe palokha zimasonyeza amodzi mwa matenda amene ali pamwambapa. M'pofunika kuchita zofufuza ena. Chofunika kudziwa ntchito ya isozyme makamaka. Ndiye kudzakhala kotheka kuti kulankhula za vuto la kutanthauzira.

Mwachitsanzo, kofunikira kwambiri akhala kuzindikiridwa isoenzymes 4 ndi 5 LDH. Ndi chiyani icho? M'malo mwake, panali imfa ya minofu minofu kapena chiwindi. Koma kuona, m'pofunika kudziwa mayesero a thupi wodwalayo zinchito.

Choncho, chifukwa LDH zofufuza tinganene kuti yekha osakaniza ndi maphunziro ena. N'kofunikanso kuti kuwunika mphamvu ya ndondomeko imeneyi kungathandize kwambiri kudziwa njira pathological.

Yafupika mlingo wa LDH

Nthawi zina zotsatira angasonyeze kuchepa mu mlingo wa LDH m'magazi. Ichi ndi chinthu mwachilungamo kawirikawiri limasonyeza kuti chamoyo ndi mwachangu amang'amba shuga ndi amalandira izo mphamvu maselo, makamaka minofu.

Utachepa LDH n'zothekanso ndi masinthidwe mbewu. Mwina awiri okha a mtundu wawo. Anthu anapezeka ndi mtundu woyamba, adzamva kutopa ndi kufooka minofu. Masinthidwe a mtundu wachiwiri alibe zizindikiro zilizonse. The kuchepa msinkhu LDH zina chifukwa kudya kwambiri kwa ascorbic asidi (vitamini C).