Kodi udindo wa estrogens mu moyo wa munthu ndi momwe estradiol kuchepetsa thupi chiyani?

Estradiol uli gulu la timadzi wamkazi, amene amapangidwa ndi kotekisi adrenal ndi maliseche. Mu thupi mwamuna ambiri estradiol opangidwa ndi nawo aromatase ndi kutembenuza anthu timadzi testosterone. Mu gulu esitirojeni Estradiol ali ndi ntchito kwambiri. Iye ali ndi zotsatira kwambiri thupi, kupanga Maphunziro Akakhalidwe Kazolengedwa a mtundu akazi, ndiponso chiwerengero cha kwambiri m'thupi. overabundance wake zinadzala ndi matenda osiyanasiyana zinchito. Izi zimaonekera makamaka mu thupi wamwamuna. Choncho, owonjezera timadzi amakhala ponseponse osati kufunika kwa funso la zochepetsera estradiol mwa mkazi, komanso mmene moyenera wokhutira mu thupi wamwamuna.

Pakuti munthu estradiol?

Ngakhale dzina lake, akazi mahomoni kugonana mbali yofunika kwambiri mu thupi wamwamuna. Estradiol kumatanthauza patsogolo fupa minofu calcium. Ndi zifika kulimbitsa ndi kukula kwa mafupa. timadzi Izi kufulumizitsa njira kagayidwe kachakudya mu thupi, amathandiza wamanjenje dongosolo ndi amalimbana "oipa" mafuta m'thupi, kuchepetsa chiopsezo cha matenda a mtima. Komanso, estradiol thandizo wamwamuna ntchito, kuchita nawo ulimi wa umuna. Zonsezi zikusonyeza kufunika kuweruza timadzi izi. Komabe, pamene owonjezera kusintha kwakukulu zimachitika mu thupi.

Chifukwa pali kufunika estradiol kuchepetsa?

Ndi kuwonjezeka mu estradiol kusintha maonekedwe a munthu. Pali kudzikundikira mofulumira minofu adipose ndi kuchepa minofu misa. Estradiol amasintha thupi, kuwapatsa iwo mawonekedwe chosalimba. Gynecomastia zambiri kumachitika chifukwa mu ponso pachifuwa. Mahomoni kulephera kumayambitsa mavuto mu dongosolo mtima. Akhoza kukhala matenda oopsa, atherosclerosis kapena infarct boma. Mosiyana ndi amene ali ndi timadzi estradiol waponya, amuna ndi milingo apamwamba matenda timadzi anavutika maganizo ndi maganizo dera. Iwo ali omumvera irritability kwambiri, nkhawa, nkhawa, ndi kutopa. Komanso, m'munsi estradiol ayenera kupewa BPH ndi mavuto ndi dongosolo genitourinary. Mukhoza kuona erectile kukanika ndipo ngakhale osabereka zolawula. Ngati muli kukaikira kulikonse za vutoli m'thupi ayenera kuchitidwa ndi magazi kukhazikitsa mlingo wa mahomoni wamkazi.

Kodi estradiol kuchepetsa?

Mankhwala kuchepa msinkhu mahomoni wamkazi mu thupi wamwamuna, mfundo ya kanthu akhoza kugawidwa m'magulu awiri. Gulu loyamba zikuphatikizapo antiestrogens. Iwo salola estradiol athe kutenga izititsogolera pa thupi. Pankhaniyi, zinthu izi sasintha mlingo wa mahomoni m'magazi. Zitsanzo za antiestrogens akhoza clomiphene, tamoxifen ndi toremifene. M'munsi estradiol pogwiritsa ntchito mankhwala a gulu lachiwiri. Mfundo zochita zawo ndi ziletsa aromatase. Kubweza kutembenuka kwa testosterone kuti oestrogens ndi mlingo ambiri estradiol yafupika. Ndi zoletsa aromatase ndi Aromasin, anastrozole, letrozole.