Kodi syndrome Alport?

syndrome Alport ndi matenda otengera kwa makolo omwe amakhala ndi kuchepetsa motsatizana mwachindunji ntchito aimpso pamodzi ndi matenda kumva kapena masomphenya. Pakali pano, ku dziko lathu la mtundu uwu matenda mwa ana (ambiri) a chimadalira pafupifupi 17: 100 000.

The zifukwa

Akatswiri amanena syndrome Alport amayamba chifukwa kuvutika mu jini, amene ankakhala mu dzanja lalitali la X khromozomu mu otchedwa zone 21-22q. Komanso, kuphwanya otchedwa dongosolo yofunika ya kolajeni mtundu 4 ndi chifukwa cha matenda. Pansi kolajeni ndi kuzindikiridwa sayansi imeneyi mapuloteni omwe ali mbali mwachindunji minofu connective amene amathandiza elasticity ndi kupitiriza.

zizindikiro

syndrome Alport zambiri choyamba zimapangitsa lokha anamva mu ana a zaka kuyambira zaka zisanu kapena khumi, ndipo anawonetseredwa mu mawonekedwe a hematuria (magazi mu mkodzo kupeza). Nthawi zambiri, matenda ndi pa mwachisawawa, ndiye pa kuona lotsatira ndi katswiri. Komanso, Alport matenda kumaonekera monga otchedwa dizembriogeneza stigmas. Izi ndi zolakwika zazing'ono kuti musakhale ndi udindo wapadera mu ntchito kwa kachitidwe zikuluzikulu za thupi. Madokotala amanena epikant (yaing'ono crease pa ngodya lamkati la diso), mkulu kumwamba, ndi mapindikidwe pang'ono makutu ndi zizindikiro zina. Amacita kumva imfa ndi chizindikiro cha matenda, ndi kumva imfa amawapeza zambiri anyamata. Onse zizindikiro zakumwamba zambiri chikaonekera unyamata, pamene wamba aakulu kulephera aimpso zimapangitsa pakokha ankangotsatira pamene akukula.

Kupeza Vuto

Alport syndrome ana kawirikawiri matenda zochokera kukhalapo kwa mtundu umenewu wa deta matenda ena m'banja. Mwachitsanzo, pofuna kutsimikizira matenda mokwanira zofanana atatu a muyezo asanu ili pansipa:

• kumva imfa;
• Nthawi imfa cha matenda aimpso kulephera abale;
• Chitsimikizo cha hematuria m'banja;
• diso kudwala;
• pamaso pa kusintha yeniyeni mkati impso biopsy.

chithandizo

Popeza mankhwala enieni, madokotala choyamba tiyenera amachepetsa mphamvu ya kulephera impso. Ndi matenda ichi monga matenda Alport, ana ndi koletsedwa kutero thupi, izo n'kukulemberani chakudya chamagulu. asamala kwambiri linaperekedwa kwa otchedwa konzanso ya foci opatsirana. Ntchito pa matenda a cytostatics ndi mankhwala osiyanasiyana m'thupi amalimbikitsa bwino. Komabe nthawi zambiri anatumizidwa impso kumuika monga mankhwala mokondera. Tikumbukenso kuti kudziwika haematuria popanda kumva imfa yokulirapo ambiri penapake yabwino kwambiri zochita za madokotala ananena zawo matenda. Mu vuto la mtundu uwu kulephera aimpso amawapeza kawirikawiri.