Prodrug "Parnavel": malangizo ntchito

Kukonzekera "Parnavel" malangizo Buku limafotokoza prodrug amene ali ndi Ace woletsa ndipo ali ndi Amowabu antihypertensive kwenikweni. The ntchito chida ichi ndi chopinga mpikisano wa Ace ntchito, kenako zikubweretsa kuchepa mu ndende ya angiotensin II. Potenga mankhwala "Parnavel" (malangizo ntchito izo akutsimikiza) yafupika preload, afterload (OPSS), ndi kukana ziwiya m'mapapo mwanga magazi, ndi kuonjezera maganizo kulolerana. Pa pharmacokinetic katundu wa wothandizira, ndiye anafotokoza kumayamba amalembedwa zotsatira hypotensive pankhondo yoyamba mphindi makumi asanu pambuyo makonzedwe kufika pazipita pambuyo maola anayi kapena asanu ndi atatu analimbikira tsiku lonse.

Mukhozanso mankhwala "Parnavel", mtengo umene umasiyana mazana awiri mphambu makumi asanu ndi rubles mazana atatu, mu mawonekedwe a mapiritsi ochiritsira chonse. The zikuchokera piritsi limodzi ngati mbali yaikulu yogwira ali nawo mwa kuchuluka kwa perindopril erbumine mamiligalamu anayi.

Makhwalawa "Parnavel" malangizo Buku akuonetsa kuti sicholinga cha mankhwala a mitundu aakulu kulephera mtima kapena matenda oopsa. Mlingo woyambilira wa mankhwala, kawirikawiri pakati ndi mamiligalamu awiri pa tsiku pa nthawi, ndi kukonzanso - mamiligalamu awiri kapena anayi pa tsiku.

Ntchito piritsi "Parnavel" Akatswiri mwamphamvu amalangiza kuti anthu ndi tsankho munthu wa perindopril erbumine komanso kwa onse amene kumakhala kutengera kuti chitukuko cha angioedema. Komanso, mndandanda wa contraindications mwachindunji kugwiritsa ntchito komanso mimba ndi zaka khumi ndi zisanu ndi zitatu. Nthawi mkaka wa m'mawere ndi ofanana sayenera kutenga mankhwala "Parnavel". Malangizo ntchito Mfundo ndi undesirability a ntchito pa nkhani ya matenda oopsa kwambiri kapena anakhazikitsa kulephera aimpso. Anthu akuvutika ndi kuchepekedwa wa madzimadzi ndi sodium, musanayambe njira ya mankhwala ayenera kuvomerezedwa kuchita otchedwa kuwukonza madzi ndi electrolyte vutoli.

Komanso, muyenera bwino ntchito piritsi "Parnavel" imodzi ndi mankhwala zimene zingachititse kuwonjezeka kwambiri mlingo wa potaziyamu.

Pomaliza, tiyenera anati za zotheka zosiyanasiyana chokhwima kuti ingayambe potenga mankhwala. Mwachitsanzo, akatswiri kuona chiopsezo mwachilungamo mkulu wa chifuwa wouma mutu, chizungulire, zipolowe za kukoma ndi pakamwa youma. Komanso, pangakhale kusintha kawirikawiri maganizo, kukanika kugonana, zotupa pa khungu angioedema, khunyu, erythema, khungu redness, kuyabwa ndi ming'oma. Komanso nkutheka kuchepetsa hemoglobin index nadzawonjezapo pa mlingo wa asidi uric ndi creatinine chifukwa ingestion "Parnavel".