Metamizole

"Metamizole" ochitachita odana ndi yotupa ake, antipyretic ndi zotsatira analgesic chifukwa chakuti ndigwire kaphatikizidwe prostaglandins ku asidi arachidonic, akusokoneza kuchititsa ululu zikhumbo kumawonjezera kutentha kutengerapo ndi kuonjezera pakhomo la ululu tilinazo.

Anati mankhwala ndi bwino odzipereka pa kapepala m'mimba, kumene hydrolyzed ndi yogwira metabolite anapanga pafupifupi theka chimamanga zonsezo magazi. Linanena bungwe mankhwala mkodzo, monga likulowerera mu mkaka wa m'mawere.

"Metamizole" - malangizo ntchito

mankhwala akusonyeza kuti kuchepetsa ululu chiyambi Kaya neuralgia, litsipa, sciatica ndi myositis. Iye analandira chimfine, malungo la misempha ndi matenda ena.

Ndi bwino kutenga "Metamizole" kuchokera mg wa 250 500 pakamwa, zimenezi ziyenera kuchitidwa 2-3 pa tsiku. Mlingo tsiku sayenera upambana 3G, mlingo umodzi sayenera kuposa 1 gram.

Ana zaka 2-3 akulimbikitsidwa kutenga mpaka 50-100 mg wa mankhwala, zaka zisanu -100-200mg, zaka zisanu -200 mg wa ndi zaka 14 -250-300mg anati njira, iwo analandira mogwirizana ndi malangizo amenewo.

Komanso, "Metamizole ndi sodium" angathe kumwedwa m'nsinga, intramuscularly, ndipo, nthawi yomweyo chikuyendetsedwera katatu pa tsiku, koma magalamu zosaposa 2 pa tsiku, ndi ana Ndi bwino kutenga 0.1-0.2 ml ya pa 10 kilogalamu thupi.

contraindications

Iwo ali osavomerezeka kutenga mankhwala pamaso pa bronchospasm, mkulu kudziwa Metamizole, matenda hematopoiesis, kumtundu hemolytic magazi m'thupi, aimpso kapena kwa chiwindi insufficiency pa mimba ndi mkaka wa m'mawere.

chingachitike mbali

Kulandira medicament "Metamizole" zikhoza zochitika monga nephritis interstitial, oliguria, mkodzo umakhala wofiira, proteinuria, anuria. Komanso, thupi lawo siligwirizana angagwe ngati conjunctivitis, urticaria, angioedema, ndi mantha nthawi zina anaphylactic angayambe, bronchospastic syndrome, Lyell syndrome. Leukopenia, kuchepa magazi, agranulocytosis, thrombocytopenia, infiltrates pa malo makonzedwe angakhalenso ngati mbali zotsatira za mankhwala.

CHENJEZO kutenga "Metamizole ndi sodium" n'kofunika pa zoopsa angapo, pamaso pa wolumikizira hypotension, m'mnyewa wamtima infarction, uchidakwa aakulu kuyambira mantha.

Ngati mukufuna kugwiritsa ntchito nthawi yaitali mankhwala, m'pofunika mosamala kapangidwe ndi chikhalidwe cha magazi zotumphukira.

Pa phwando munthawi yomweyo ndi chlorpromazine angathe hyperthermia. "Metamizole 'sali pamodzi benzylpenicillin mmalo colloidal magazi ndi zinthu radiopaque.

Cholinga cha mankhwala ndi kulera m'thupi, analgesics sanali chomwa mankhwalawa, allopurinol ndi antidepressants tricyclic zikhoza kumatheka zotsatira poizoni.

Likupezeka "Metamizol-Sodium-Pitofenone Fenpiveriniya bromide" yomwe ndi njira ophatikizana kupereka spasmolytic ndi analgesic zotsatira.

Ngati ambiri osokoneza amapezeka nseru, oliguria, omangana, gastralgia, magazi kuchepetsa kuthamanga, hypothermia, dyspnea, tachycardia, tinnitus, lightheadedness, kugona, pachimake agranulocytosis ziwalo za minofu kupuma, mkhutu chikumbumtima, matenda hemorrhagic.

Zikatero, chapamimba lavage imagwiridwa ntchito kafukufuku analandira saline Mankhwalawa ndi nthawi adamulowetsa mpweya. angathe kuchitidwa hemodialysis, anakakamizika diuresis, ndi pamaso pa omangana - mu / ntchito diazepam kutumikiridwa ndipo mofulumira akuchita barbiturates.