Mankhwala 'Manini': malangizo ntchito

Kukonzekera "Mannino" malangizo Buku limafotokoza ogwira antidiabetic mankhwala kuti kaundula alendo (mayiko Nonproprietary Mayina) dzina ndi "Glibenclamide". mankhwala ndi mphamvu yaikulu pokonzekera, amene amapangidwa ndi opanga mu mawonekedwe a mapiritsi, masekeli 1,75 mg kapena 3.5 mg. The zikuchokera mankhwala monga mankhwala othandiza mulinso lactose monohydrate, silika, chakudya zowonjezera E 124 - tinatake utoto, wowuma mbatata, gimetelloza.

The katundu pharmacokinetic mankhwala malinga glibenclamide - yaikulu yogwira mankhwala - uli mu chiphunzitso mu mawonekedwe micronized. Izi zimathandiza kuti mlingo malowedwe a mankhwala ndi kuonjezera dera suction ake. Komanso, aluso mayamwidwe zigawo mankhwala kumathandiza methylhydroxyethylcellulose, yomwe ndi mbali pokonza "Mannino".

Malangizo ntchito akufotokozera kuti zowonjezera anali pafupifupi ziribe mphamvu pa dziko la thupi, koma, ngakhalebe, limachititsa ndithu kwambiri pa zogona nthawi ya zigawo zikuluzikulu za mankhwala mu gawo omwazika, zipatso kwambiri zochita zake. Pa imeneyi ndende ya mankhwala mu zigawo plasma kumawonjezera katatu asanu, motero pali kuchepetsa kwambiri kuchuluka kwa shuga.

Medicament "Mannino" amadziwika onse kalozera kumafuna chuma mofulumira odzipereka kwa thirakiti m'mimba ndi mawonekedwe ake micronized wa glibenclamide limathandiza kwathunthu kumasulidwa ku mankhwala wothandiza mu thupi kwa mphindi zisanu. Amenewa limachititsa kutenga mankhwala basi pamaso chakudya, 5 - 10 Mphindi pamaso. Pachimake ndende amapezeka kukonzekera kale, ndi kanthu ake Choncho, ndi thupi. Ngakhale mfundo phwando munthawi yomweyo chakudya alibe zotsatira kwambiri pa zochita za mankhwala. Kukonzekera "Mannino" ali ndi mlingo wa 100% bioavailability. Ake theka moyo wa chamoyo ndi avareji ya imodzi ndi theka maola atatu ndi theka.

Nthawi khola hypoglycemic zotsatira za glibenclamide anakhalabe tsiku lonse.

The katundu pharmacodynamic mankhwala, "Manini" malangizo Buku limafotokoza motere. Medikamet Izi zikhoza kusintha katulutsidwe wa insulin pamene suction ku maselo beta a kapamba, ndi mankhwala timapitiriza insulin tilinazo, amene zimatheka ndi kukondoweza kwa cholandilira insulin.

Komanso, glibenclamide akhoza kuchepetsa kanthu za kupatsidwa zinthu za m'mwazi kupewa m'mnyewa wamtima ischemia. The mankhwala ali kanthu njira ndi arrhythmias mtima.

Monga kukhazikika bwino, mankhwala potero kuchepetsa ngozi ya mavuto a shuga (mtundu 2), monga matenda ashuga cardiomyopathy, nephropathy ndi retinopathy. Medicine "Mannino" malangizo Buku limafotokoza monga njira kuchepetsa mlingo wa imfa matenda kugwirizana ndi shuga.

The zizindikiro zazikulu ntchito glibenclamide - shuga a mtundu wachiwiri, pamene zakudya mankhwala anasonyeza zotsatira mtima. Miyala "Manin" angagwiritsidwe ntchito ngati woima achire wothandizira, ndi mbali ya osakaniza mankhwala ndi mankhwala ena odana ndi matenda ashuga.

Ziyenera adzanyamula kukumbukira kuti nthawi ya mankhwala ndi mlingo wa mtengo anatsimikiza ndi dokotala zochokera njira payekha la wodwalayo. Pa siteji koyamba mankhwala anapereka Mlingo wocheperako zakayendesedwe ka mankhwala. Ndiye, kudzudzulidwa mode ntchito, pamodzi ndi kuwukonza chakudya. Tsatanetsatane wa kamwedwe mlingo limafotokoza malangizo ntchito mankhwala.

Muyezo waukulu kusintha mlingo ndi mlingo wa shuga.

Kulandira glibenclamide akhoza kuyambitsa zotsatira zoyipa, ambiri amene ali hypoglycemia. zizindikiro zake ndi thukuta mwadzidzidzi, kugwedeza, mutu, matenda a ubongo ndi ena.

Contraindications kuti utsogoleli wa mankhwala ndi hypersensitivity ku zigawo inefficiencies chithandizo sekondale ndi "Mannino", ketoacidosis, matenda zinchito a impso ndi chiwindi.

Palibe mfundo zokwanira pa ntchito mankhwala a ana amene zaka alibe upambana zaka 18.

Musagwiritse ntchito mankhwala pa Kuyamwitsa ndi pa mimba.

Kusunga mankhwala ayenera kukhala pa kutentha osati oposa 25 C. Mu zikhalidwe za yosungirako alumali moyo wa mankhwala ndi zaka 3.