"Indapamide" - malangizo ntchito

Indapamide "- mankhwala cha gulu la kukodzakodza thiazide zimakhudzanso antihypertensive. Medicine "Indapamide" anasonyeza ntchito mu kukhalapo kwa matenda oopsa.

Pharmacological kanthu "Indapamide" mankhwala

Guide limanena kuti katundu pharmacological mankhwala ndi zokhudzana okodzetsa thiazide. Ndinakumana ndi mankhwala angathe kusankha kutsekereza "m'mbuyo" kashiamu njira kumathandiza kuti elasticity wa pakhoma wolumikizira, limene pali kuchepetsa okwana zotumphukira mtima kukana.

"Indapamide" susintha zimam'patsa kagayidwe, zomwe ndi zoyenera kwa odwala matenda a shuga, ndi sikumangotikhudza ndende za lipids ku plasma. Miyala "Indapamide" amathandiza kuchepetsa hypertrophy wa ventricle kumanzere, kukupundula mtima makoma kwa norepinephrine ndi angiotensin II, kumapangitsa kaphatikizidwe wa prostaglandin E2, kuchepetsa kupanga ankafuna kusintha zinthu mopitirira oxygen. Kawirikawiri 5-7 tsiku chithandizo ndi zotsatira antihypertensive akuwonekera, kupitiriza ndi mlingo umodzi masana.

Pharmacokinetics "Indapamide" mankhwala

Guide inanena kuti mankhwala yodziwika ndi bioavailability mkulu (93%) ndi mayamwidwe kapepala kakuti m'mimba. Pa mlingo wa mayamwidwe umakhudza kudya chakudya. Ndende apamwamba mankhwala magazi analengedwa mu ola limodzi kapena awiri pambuyo kutenga mankhwala mu kuchuluka kwa 2.5 mg. mankhwala ndi zimapukusidwa ndi chiwindi. 60% -80% zakuthupi ndi linanena bungwe kudzera impso mu mawonekedwe a metabolites, pafupifupi 20% - kudzera intestine lapansi. Mankhwala alibe luso cumulating.

Zikuonetsa "Indapamide"

Malangizo n'kukulemberani mankhwala kwa kutsitsa magazi. Komanso, mankhwala tikulimbikitsidwa kuti anthu aakulu ikudontha kulephera mtima.

contraindications

"Indapamide" ali contraindicated mu:

- kuchuluka kudziwa izo, ndi ena ofanana zina za gulu sulfonamide,

- anuria,

- hypokalemia,

- aakulu kwa chiwindi kapena insufficiency aimpso,

- nthawi ya mkaka wa m'mawere,

- pachimake kudwala wa kufalitsidwa oziziritsa,

- mimba,

- zaka 18 (chifukwa cha kuda)

- makonzedwe munthawi yomweyo asatayike kuwonjezeka nthawi QT.

CHENJEZO kutumikiridwa mankhwala pamaso pa gout ndi matenda a shuga decompensation.

N'zimene ndi n'zimene mankhwala "Indapamide"

Guide amalimbikitsa mukumwa mapiritsi mkati, osati madzi. 2.5 mg (tsiku mlingo) bwino ntchito m'mawa kapena masana. Pamene 1-2 miyezi ya mankhwala sikunapangitse kufunika kwenikweni achire, mlingo ali osavomerezeka kuonjezera chifukwa chiopsezo mavuto kuchuluka. Pankhaniyi, mankhwala mankhwala a matenda oopsa chiwembu ayenera kuwonjezera wothandizila wina antihypertensive kuti si diuretic. Popereka chithandizo awiri antihypertensive mankhwala mlingo "Indapamide" akanali yemweyo.

ambiri osokoneza

Zizindikiro ambiri osokoneza ali kuwonetseredwa ndi kufooka, kuphwanya ntchito m'mimba, nseru, kusanza, madzimadzi ndi zipolowe electrolyte. Mu zina kumachitika ambiri osokoneza maganizo kupuma ndi kumwetsa kutsitsa magazi. Mu odwala matenda a chiwindi angayambe kwa chiwindi chikomokere.

Pankhaniyi cha mankhwala osokoneza bongo ayenera idzachitika kukonzedwa kwa matenda madzi electrolyte bwino: a lavage muzituluka ndi mankhwala symptomatic.

mogwirizana

Angathe zotsatira za mankhwala ena kuthamanga kwa magazi. Musati zimagwirizizirana ndi mankhwala okhala lifiyamu, vincamine, kaliyvyvodyaschie okodzetsa.

Zotsatira zoyipa za mankhwala "Indapamide"

Mofananamo, milandu cha mankhwala osokoneza bongo. Mwina chisokonezo mtima mungoli chifukwa imfa ya potaziyamu. Komanso, mavuto kumachitika kufooka, kuchepa lakuthwa mu kuthamanga pamene waima, nseru, kupweteka m'mimba, kutsekula m'mimba, kupweteka, thupi lawo siligwirizana. Nthawi zina, achuluke gout, omangana.