Duchenne myopathy - matenda ya ubongo.

Matenda ya ubongo nthawi zonse kale mwa zovuta kwambiri ndi zovuta ndi mankhwala chithandizo cha zinthu pathological. Ichi ndi chifukwa chakuti mantha dongosolo ndi zapamwamba kwambiri ndi kwambiri kusiyanitsidwa Kapangidwe ka thupi la munthu, maselo amene pafupifupi sangathe kudzichiza lokha. Ngati pali kuwonongedwa kwa mitsempha CHIKWANGWANI wosakwatiwa, zodabwitsazi ndi kulisiya kwathunthu. The chifukwa cha ndondomekoyi chingandithandize imfa yosatha ya luso zinchito za dera anatomical, zimene ulusi mitsempha kukumana otaika. matenda ambiri a ubongo ndi chifukwa cha nthenda ya kumtundu kuti akhoza opatsirana ku mibadwomibadwo.

A chitsanzo chapadera cha chikhalidwe chibadwa anachititsa pathological ndi Duchenne myopathy. matenda amenewa imafalikira mu autosomal recessive cholowa anachita ndi zambiri awonetsedwe pakati pa anthu wamwamuna wa lathuli. Mfundo yomalizayi ndiyo chifukwa chakuti cholowa kumayambitsa DNA kugonana. Pa matenda mtima ndi jini chilema udindo kaphatikizidwe yofunika kwambiri ya dystrophin mapuloteni, zomwe zimafunika kuteteza dongosolo anatomical a minofu CHIKWANGWANI. Chifukwa chosowa mapuloteni dystrophin minofu minofu amaloŵamo angapo kusintha chifukwa cha zomwe minofu m'malo mwa fibrous ndi mafuta minofu, mwa kulankhula kwina, izo manja. Chifukwa chakuti Duchenne myopathy ndi cholowa, zimayamba kuoneka mwamsanga wakhanda. Makolo kulabadira zimene mwana matayala awo mosavuta ku yaikulu pang'ono thupi, amakhala aulesi, mwamsanga iye akhoza ngakhale kusintha gait ndi opunduka fupa mafupa.

Kenako pathological ndondomeko m'kati yekha kuyambira Ndi phunziro kwa mwamtheradi onse minofu ya thupi la munthu. Pakuti kudwala imeneyi amakhala ndi myopathy diso. More minofu ndi akhudzidwa miyendo, torso, mtima. Pamene okhudzidwa m'mnyewa wamtima, pali cardiomyopathy sekondale, wosweka mtima mungoli. Nthawi zambiri ndi kudwala a dongosolo mtima ndi chinthu chachikulu chomwe kufa kwa wodwala ndi matenda a Duchenne myopathy. njira kwakukulu ya chithandizo cha matenda ichi palibe. Mfundo yaikulu ya mankhwala - ndi kusintha khalidwe ndi kutambasuka kwa moyo wa munthu.

Myopathy Duchenne akhoza kulipidwa kwa nthawi yaitali ndi kulandira mankhwala corticosteroid. Pafupifupi wodwala tsiku muyenera za 800 mg wa prednisolone pa kilogalamu ya kulemera kwa thupi. Mu masiteji koyamba zimathandiza kwambiri mapuloteni maofesi ndi okhutira mkulu wa amino zidulo, anabolic mankhwala, ndiye onse kuti ungawonjeze kukula kwa minofu minofu. Mankhwalawa chofunika monga L-carnitine, mankhwala vasoactive, mavitamini (B1, B6, B12, etc.) Biogenic stimulators (Aloe), alpha-lipoic asidi, zinthu ku gulu la antioxidants. Mu zonse za izi njira kudwala ayenera anachita, zomwe patsogolo trophism mu musculature lapansi. Iyi ndi njira physiotherapy osiyana, magawo thupi mankhwala ndi zonse achire kutikita. Zonsezi zimathandiza kuchepetsa kupitirira kwa matenda ndi chitukuko cha olowa ndi minofu contractures, amene kwambiri kuchepetsa galimoto ntchito za mtima. Kuchepetsa stiffness mafupa ntchito njira zosiyanasiyana ndi zomangamanga. Mu zambiri aakulu milandu, pamene kutchulidwa contracture ndi kuteteza osati kuyenda, koma ngakhale kukhala ndi bodza kuti amathamanga palliative opaleshoni.