Acetone Halitosis

Ena kunja kusintha thupi monga zotupa khungu discoloration, makamaka sputum, pakamwa fungo, wachita kale kuonedwa ndi madokotala matenda a matenda ena. Kafungo kabwino zosasangalatsa fungo la mkodzo, khungu kapena m'kamwa ndi zizindikiro za matenda osiyanasiyana: shuga woyamba kapena wachiwiri mtundu, syndrome atsetonemichesky, matenda a mtima, matenda ndi zizindikiro zina matenda. Fungo la acetone mpweya mwana kapena wamkulu chafotokozedwa ndi zikamera wa munthu limagwirira zovuta kumvetsa zambiri sikudalira zaka. Ichi ndi chifukwa kuwonjezeka anthu matupi magazi ketone: acetoacetate (H3C-NKHA-CH2-COOH ) ndi β-hydroxybutyrate (H3C-CHOH-CH2-COOH ).

boma kagayidwe kachakudya chimene chayambitsa ndi woipa mkulu wa matupi ketone inakhazikitsidwa m'zaka kuwonongeka zidulo mafuta, wotchedwa ketoacidosis. Ndi chikhalidwe pathological njira kagayidwe kachakudya ndi chifukwa chakuti thupi sangathe mokwanira zonse kupanga ketones, keto zidulo kudziunjikira chifukwa cha kusintha ndi magazi pH. Nthawi kwambiri ketoacidosis akhoza chakupha. boma kagayidwe kachakudya ndi ambiri mu shuga yoyamba.

ntchito yaitali mowa amapezeka ketoacidosis mowa, pamene limapezekanso acetone mpweya fungo chifukwa zili acetone mu mpweya, umene ndi chochokera kwa oipa mowiriza asidi acetoacetic. Nthawi anafotokoza monga madzi fungo osalala remover.

Pa woipa mkulu wa shuga m'magazi (hyperglycemia), chifukwa kupanda insulin (woyamba mtundu shuga) kapena maselo kulephera kuumbidwa ndi insulin (mtundu lachiwiri la shuga) akutitsogolera kuti kuwonjezeka kwa acidity wa magazi. Mu anthu athanzi, kawirikawiri sizichitika chifukwa kapamba umabala mankhwala okwanira, kapena maselo bwino amalabadira zokwanira kwaiye wa timadzi ndi kapamba. Chifukwa, shuga akulowa maselo (sali njala), ndende zake magazi si kukula, ndi salabadira za kuwonjezeka mu ndende ya matupi magazi ketone. Choncho anthu athanzi (akudwala palibe shuga) acetone mpweya fungo kwina.

Mu odwala matenda ashuga, ketoacidosis limodzi ndi hyperglycemia (mkulu shuga seramu) ndi ludzu (madzi m'thupi). Oversupply shuga kungayambitse yopanga kusalankhula za matupi ketone (kudzera kagayidwe mafuta acid), ndi chikhalidwe chimene chili ndi fungo la acetone mpweya mwana kapena wamkulu. Chifukwa ndi zimamuchulukira aimpso, shuga mkodzo limapezeka (a chodabwitsa otchedwa glucosuria), womwe wathanzi chamoyo ndipo resorbed ndi impso kumbuyo mu m'magazi. Contact ndi shuga mkodzo chifukwa cha ndende ake apamwamba mu magazi kumathandiza kuti imfa madzimadzi. Ashuga ketoacidosis ndi zoika moyo pangozi anthu odwala matenda a shuga. Izi zimachitika makamaka odwala ndi mtundu shuga, koma kuti nthawi zina, zimachitika anthu a mtundu II shuga.

Mu mowa ketoacidosis mowa amachititsa madzi m'thupi ndi kutsekereza Tikafuna gluconeogenesis - kagayidwe kachakudya njira wopita ku m'badwo wa shuga ku magawo sanali zimam'patsa mpweya monga lactate, glycerol ndi ena. Ichi ndi chimodzi mwa zifukwa ziwiri zazikulu ntchito mwa anthu ndi nyama zina mwa thupi akhalebe amphamvu shuga m'magazi, amene amathandiza kuti musakodwe otsika kwambiri (chikhalidwe wotchedwa hypoglycemia). njira zina kukhala magazi shuga msinkhu ndi glycogenolysis - processing glycogen (zimam'patsa malo). Ngati thupi alibe kuchuluka okwanira shuga maselo mphamvu, analenga mavuto mphamvu, chifukwa cha zimene mafuta asidi kagayidwe ndi ketone matupi anapanga limapezeka acetone mpweya fungo.

Zofewa acidosis chingachitike n'chiyani yaitali kusala kapena zakudya ketogenic (chakudya m'gulu zakudya zokhala ndi mkulu kuchuluka kwa mapuloteni ndi mafuta, otsika chakudya) chimene mankhwala makamaka ntchito pofuna kuchiza unmanageable khunyu ana, matenda a mtima, kutopa syndrome ndipo limati zina. Low-zimam'patsa zakudya analamula kuti kulemera kulamulira ndi chithandizo cha kunenepa, komanso kuchepetsa kudya chakudya. Pa siteji koyamba chotero zakudya akusowa glycogen, pafupifupi tsiku. Ndiye, thupi amagwiritsa kwa magwero njira mphamvu (mafuta ndi mapuloteni), amene anapanga pa oipa a matupi ketone, ndipo zikuoneka acetone mpweya fungo.