PSA mayeso - ponseponse. Kodi kutenga magazi kuti PSA, oyenera lokonzekera

khansa Prostate ndi "wolemekezeka" malo wachitatu mu imfa mwa khansa ina, ndipo gulu la akulu ndi mtsogoleri. Mu Russia yekha, pali pafupifupi 14,000 milandu matenda chaka chilichonse. Panthawi yake matenda ndi nthawi yake kuchitapo kanthu amathandiza PSA mayeso. Kodi ndi mmene kukonzekera, kuti zinali zolondola?

Kodi zikutanthauza PSA ndi acronym?

PSA kapena PSA - Prostate wothandizila mwachindunji. Pa kapangidwe ake, ndi mapuloteni polypeptide ongokhala kwa amino zidulo zoposa 200. Ndisonyezeni mankhwala ndi odwala ndi wathanzi maselo prostate, wamng'ono kukhalapo kwake mu magazi likusonyeza PSA mayeso. Mlingo uliwonse msinkhu wa amuna nazo kuyambira zaka Prostate wothandizila yeniyeni opangidwa ku ochuluka. Mu amuna wathanzi pano, kuwonjezera pa magazi ejaculate (umuna) ndi prostate chinsinsi. Mu kukhalapo kwa maselo khansa Prostate wothandizila wayamba kusindikiza mabuku chachikulu, ponena zolakwa wopanda chodetsa matenda. Kuwonjezera Kupeza Vuto matenda, kuwunika imagwiridwa kuti kuwunika thanzi la kale ankachitira kapena pansi chithandizo cha odwala matenda a kansa kapena BPH.

mchikhalidwe zaka

Khansa - matenda sioneka kwambiri. Ngati si wapezeka nthawi ndi kuyamba mankhwala mochedwa, izo zivute zitani kumabweretsa imfa. Malinga ndi ziwerengero thanzi, mtundu wa khansa si kugwirizana ndi kusuta, kumwa mowa mwauchidakwa, ndi mphamvu za kugonana ndi matenda opatsirana pogonana, ndiye iwo akhoza kudwala munthu aliyense. Kudziŵa kokha yake kudziwa matenda, ndipo potero kupulumutsa moyo wake ndi mayesero PSA magazi. Voterani akhoza kuposa yochepa, amene amagwirizana ndi matenda ena. Zikatero, kubwereza kusanthula kapena kafukufuku zina.

ndi "imvi m'dera" n'chiyani?

Kuti mudziwe kutenga magazi kuchokera mu mtsempha wa. Zotsatira za kuwunika pamene mfundo pamwamba yachibadwa Prostate wothandizira, koma musalumphe 10 ng / mL, amatchedwa "zone imvi". Zikatero, dokotala angakupatseni ndi Prostate biopsy. The chosonyeza chachikulu makhalidwe ake ndi chiŵerengero cha otchedwa ufulu PSA kwa chonse pamodzi. Ndi anthu athanzi akhale pamwamba 15%. Otchedwa ufulu PSA zofufuza ndi mtima wa chiwerengero cha sanali (mfulu) mapuloteni wa wothandizila Prostatic ali seramu. mfundo ndi yakuti peresenti zokha 10 a mitundu yonse Prostate wothandizila azipereka M'boma lino. Peresenti yotsalayo 90 amagwirizana ndi mwina α-1-antichymotrypsin (protease woletsa) kapena α-2-macroglobulin (woletsa wa pepsin, plasmin ndi michere zina). Ngakhale molumikizana ndi α-2-macroglobulin, PSA pafupifupi zotsimikizika. mayesero Laboratory amasonyeza chokha chiwerengero cha ufulu ndi womangidwa ndi α-1-antichymotrypsin Prostatic wothandizira. phindu okwana limasonyeza otchedwa magazi okwana PSA. Ngati mwamuna khansa prostate, mu thupi la α-1-antichymotrypsin amayamba kutulutsa lalikulu zedi, chifukwa mu wothandizira wamkulu kumangako ndi kuchepetsa mu mawonekedwe ufulu. Choncho, kuchuluka kwa mitundu iwiri yafupika.

Chifukwa pamwamba mwakale chiyani?

Pa zigoli za PSA mu zitsanzo magazi seramu zimakhudza kwambiri matenda ena. The owopsa a iwo - khansa, mwachitsanzo, zilonda Prostate kukulitsa, kumphatikiza ndi zaka ndipo amapereka metastases. Pa kukayikitsa pang'ono khansa akuwonetseredwa mu ululu pokodza, kumverera ngati chikhodzodzo si kwathunthu anadzikhuthula, kawirikawiri Tisaiwale ndi bvuto ndi pokodza ndi ululu perineum ndi, m'pofunika kupanga PSA mayeso. Norma ndi mmene anthu athanzi, kuchuluka mlingo akhoza kukhala matenda otsatirawa:

- adenoma (chosaopsa chotupa kuti si metastasize);

- kutupa prostate;

- infarction (necrosis chifukwa kuphipha);

- ischemia (Prostate magazi m'thupi kugwirizana ndi mavuto m'zotengera mwazi);

- pachimake aimpso kulephera.

Kodi ndi zinthu ziti chifukwa ponso prostate-wothandizila?

chiwerengero cha Prostate wothandizila mu magazi bwanji zifukwa zingapo. Choncho, pofuna kupeza yodalirika PSA mayeso kukonzekera kwa izo zizichitidwa mokhudzika. Pakuti ndikukondwera kwakukulukulu malamulo kusonkhezera:

- umuna;

- kwambiri kutikita a prostate;

- biopsy;

- TRUS (Prostate yeniyeni ultrasound);

- TURP (opaleshoni mmene prostate).

Zinthu zimene musati bwanji kuwerenga:

- nthawi ya tsiku;

- oyamba a catheter mu chikhodzodzo ndi cystoscopy;

- thumbo (ndi zala) a prostate.

Kukonzekera kwa kusanthula

Wodwala aliyense chofunika kudziwa ndi kutsatira mosamalitsa ndi zofunikira za maphunziro tisanasankhe pa PSA mayeso. wakudziko ake kwa mibadwo yonse ziri zodziwika bwino. Mlingo sangathe kuchuluka chifukwa matenda prostate, koma chifukwa cha sanali kugwilizana ndi zinthu zapadera. Iwo ali motere:

- kupewa ndi umuna kwa masiku osachepera 2 isanafike kusanthula;

- kuonetsetsa bwino kale kuposa masiku 3 pambuyo kutikita zozama za prostate;

- ngati mtima wa imagwiridwa TRUS, pambuyo ndondomeko pamaso PSA kuyezetsa akhale masiku osachepera 7;

- pambuyo Prostate biopsy, amene kumawonjezera kwambiri kuchuluka kwa wothandizila mu magazi, ayenera kukhala osachepera 6 masabata isanafike kusanthula;

- Ngati wodwala anali resection transurethral, PSA chiyeso kuchitidwa osati kale kuposa miyezi 6 pambuyo opaleshoni.

Komanso, isanafike kuwunika, ndi zofunika kupewa kusuta, tsiku kuposa munthu kudya zakudya mafuta, kupewa kwambiri thupi ndi maganizo yaikulu.

Pamene kutumikiridwa kusanthula?

Pamene amaganiziridwa matenda Prostate ndi mankhwala a zotupa wapezeka kutumikiridwa PSA kusanthula. Norma kulandira chithandizo kumatengera mtundu wa mankhwala. Choncho, pambuyo opaleshoni kuchotsa prostate (LRP) digito chizindikiro Prostate wothandizila yeniyeni nthawi kusanduka 0.2 ng / ml, ndipo pambuyo mankhwala cheza - mpaka 1 ng / ml. zizindikiro izi ndi zabwino kwambiri ndi kulola ife kuti choyembekezera nthawi yaitali popanda musabise. Ngati mitundu yonse ya amawonjezera mankhwala PSA, akhoza anati pofuna kukwaniritsa khansa. Komabe, muyeso wa mfundo PSA kuti si nthawi zonse akulankhula za khansa. Nthawi zina, zotsatira zake zimakhudza mbali wodwala aliyense wa zopinga minofu. Pali anthu amene ali ndi mwai permeability nsalu, kotero Prostatic wothandizila mosavuta likulowerera mu magazi, ndipo monga Motero, kuchuluka penapake anakokomeza.

Kodi miyezo ikuchitika kutsimikiza matenda?

Monga ndanenera pamwamba, ndi zaka prostate Amamchulukitsira yense. Kuchepetsa mphamvu ya kuwonjezeka chibadwidwe zotsatira za kufufuza ndi anayeza PSA osalimba. index Izi anatsimikiza ndi kugawa zigoli amayezedwa Prostate buku. Ngati quotient akamagwira kugawa kukhala pamwamba 0,15 ng / ml ya / kiyubiki cm, pali kukayikitsa isanayambike kusintha pathological prostate. Zikatero, biopsy anthu. mtundu wina wa kafukufuku ndi kudziwa liwiro amene asintha PSA. Ngati index mtengo pamwamba 0,75 ng / mL / chaka, wodwala kwambiri Mwina chitukuko chotupa. Data kusanthula kuthandiza molondola zokwanira kuti azindikire pamaso pa metastasis wodwalayo. Choncho, pamene anasonyeza Prostate wothandizila yeniyeni pamwamba 50 ng / ml ya n'zokayikitsa mkulu wa ndondomeko metastasis wayamba. manambala A pamwamba 100 ng / mg wa akaone kupezeka kwa metastasis kwambiri.