Myeloma angapo

Angapo myeloma (matenda Rustitskogo Clair) ndi wina kuposa mafupa chotupa chimene chiri chopangidwa ndi maselo plasma wokhwima osiyana. Kufotokozera za matenda analipo m'zaka za m'ma XIX. Kwenikweni, matenda umamumvera mbali wamkulu wa anthu ndi okalamba.

Akukhulupirira kuti zotsatira za myeloma angapo ndi masinthidwe a B-lymphocytes. matenda ndi kuchuluka pathological maselo plasma, imbaenda kuwonongedwa kwa fupa mankhwala ndi chiwonongeko fupa. Chifukwa cha njira, fractures pafupipafupi ndi kusintha mawonekedwe awo. Anakulira ambiri, maselo plasma kubala paraprotein, kuchititsa kuwonjezeka kwa mapuloteni okhutira m'magazi. Hyperproteinemia zimayambitsa matenda a impso ndi chitukuko cha zochitika kulephera aimpso. Zochotsa mu tubules ndi, paraprotein amachititsa nefrogidroz ndi amyloidosis.
Kukula kwa matenda kumabweretsa kusintha pathological m'magazi, mkhutu hematopoiesis. Mu M'chithunzithunzi munakwanisa kuona magazi magazi, maselo othandiza magazi kuundana otsika magazi ndi maselo oyera.

mawonetseredwe matenda

Angapo myeloma si nthawi yaitali zimapangitsa lokha anamva, ndipo alili akhoza kukhala zogwira mtima. Mu nthawi yoyamba ya matenda kuoneka malaise, kutopa, asthenia. Kawirikawiri, ndi chizindikiro choyamba chomwe chimamulimbikitsa kuwona dotolo, ndi ululu m'munsi kumbuyo, msana ndi mafupa, ndi ululu amamuchititsa kuonjezera. Zizindikiro Komanso akhoza kugwirizana ndi mkhutu hematopoiesis (kuchepa magazi, thrombocytopenia), kukhala hemorrhagic matenda, m'mnyewa wamtima viscera, thromboses. Mkati mwa zizindikiro matenda zokhudza kuwonjezeka insufficiency aimpso ndi Hyperproteinemia.

diagnostics

Mu nthawi koyamba pali kuwonjezeka mu magazi erythrocyte sedimentation mlingo kuti zotsatira dysproteinemia. Ndi kupitirira la ndondomeko kuoneka magazi m'thupi, kuchepa maselo othandiza magazi kuundana ndi leukocytes. Mu kusanthula imfa mkodzo mapuloteni anati lalikulu. Pamene kusanthula amuzolengedwa magazi anatsimikiza ndi kuwonjezeka kwa okwana mapuloteni. Ndi zizindikiro za kulephera impso - kuwonjezeka creatinine ndi urea, electrolyte vutoli.
The matenda a "myeloma angapo" walembedwa zochokera chifukwa cha kusanthula maselo mafupa. Izi ndi matenda ntchito yaikulu. Mthandizi njira ndi kuchita X-ray fupa kudziwa zopindika ndi deformities fupa, zotupa kufooka kwa mafupa. Iwo m'pofunika kuchita proteinogram.

Chithandizo cha zingapo Myeloma

Ngati kuyenderako anapeza myeloma, chithandizo cha matenda chibwenzi - vuto osathetsedwa. Iwo ayenera kudziwa nthawi ya moyo wa odwala ndi chithandizo chabwino ndi ndi mosabisa njira ya matenda ndi zaka pafupifupi zisanu. The mankhwala a matenda ntchito medicaments zomwe ziletsa chotupa chitukuko (cytostatics). Koma mankhwala amenewa kutalikitsa moyo wa odwala. Pa chiyambi cha mankhwala Kwalamulidwa mu Mlingo wa mantha akamaliza njira kusinthitsa mankhwala yokonza.

"Prednisolone" ntchito limodzi ndi mankhwala cytotoxic. ntchito zake kumabwezera mmbuyo kuwonongedwa kwa fupa ndi kuli ndi ubwino ndi kuwonjezeka mu kashiamu ndi. regimens otukuka monga ma angapo mankhwala, mlingo wosiyana malinga mwamphamvu ndi mtundu wa myeloma. Zotsatira zochiritsira ayesedwa itapita miyezi itatu pambuyo chiyambi cha mankhwala amphamvu.

Pa inalowa, aimpso kulephera, kungafune chithandizo pulogalamu hemodialysis.

Mwina ntchito mankhwala cheza. Iwo Kwalamulidwa zochizira mfundo zochepa chotupa ili mu mafupa ndi zimakhala zofewa.