Mapiritsi pa zoipazi "Fiziotenz": mayankho a odwala ndi madokotala

Kugwiritsa antihypertensive mankhwala, ndi kusankha imidazoline cholandilira agonist ndi mankhwala "Fiziotenz". Umboni kuti njira kumathandiza kuchepetsa kuthamanga kwa odwala matenda ashuga ndi anthu misa mkulu thupi.

oopsa Features

Matenda a zotengera mtima ndi magazi omwe ali ndi anthu ambiri. Komabe, akazi zolakwika awa kukhala mochedwa kuposa amuna. Koma zidzachitika zambiri zovuta ndi yodziwika ndi amadwala magazi, yapadera kwambiri zizindikiro zopweteka kwambiri. Oopsa pafupipafupi akufotokozera ndi pathologies ena: kunenepa, shuga, matenda a chiwindi ndi kulephera impso zamadzimadzi kagayidwe.

Pamodzi ndi kuwonjezeka mu misa thupi amapezeka kusokoneza SNA, ndilo chifukwa chachikulu cha kuthamanga kwa magazi ndi matenda oopsa mapangidwe. Allocated symptomatic mantha dongosolo mahomoni zimathandiza luminal kuchepetsa Mitsempha, chifukwa mu mtima pokamba za mpweya zimakhala ndi ziwalo kudzikakamiza magazi makokedwe pansi kuthamanga, Izi zinachititsa oopsa, amene nkhani azichitira mankhwala njira. Mmodzi wa mankhwala, ndi kulola kuthamanga zithetsedwe, ndi njira "Fiziotenz".

Kapangidwe ndi Kaonekedwe

Yopangidwa medicament mu mawonekedwe a mapiritsi filimu TACHIMATA. Waukulu yogwira zochita mankhwala moksonindin. The zigawo zikuluzikulu wothandiza monga mankhwala enaake a stearate, crospovidone, povidone, lactose monohydrate.

katundu pharmacological

Thunthu yogwira medicament ali ndi chapakati hypotensive kanthu. Moxonidine maselo tsinde ubongo kusankha kumapangitsa zolandilira imalandira, amene mukugwira nawo lamulo la zimandilimbikitsa reflex ndi symptomatic mantha dongosolo. Chifukwa ndi kuchepa mu ntchito ndi symptomatic zotumphukira wolumikizira kuthamanga. Kafukufuku wosiyanasiyana (placebo-ankalamulira, osapanganika, awiri akhungu) kutsimikizira mphamvu ya mankhwala "Fiziotenz". Reviews odwala zimatsimikizira kuti mankhwala isiyana ndi zina sympatholytic wothandizila antihypertensive amene amayambitsa pakamwa youma, pamene ntchito palibe sedation.

Pharmacodynamics ndi Pharmacokinetics

Pambuyo kulandiridwa mumtima zikutanthauza 90 peresenti odzipereka kwa dongosolo gastro-m'mimba. Ndende pazipita thunthu yogwira mu madzi a m'magazi zimawonedwa ola. Chakudya pa pharmacokinetics wa moxonidine alibe chochita.

Akuluakulu metabolite yogwira pawiri ndi dehydrogenated moxonidine ndi guanidine ofanana nawo. Theka moyo wa moxonidine amapezeka mkati maola 2.5 ndi tsiku pa 90% linanena bungwe mchitidwe kudzera impso ndi matumbo.

Mu odwala matenda oopsa, poyerekeza ndi anthu athanzi, kusintha mu pharmacokinetics wa moxonidine anali kudziŵika. Pang'ono magawo kayendedwe akhoza kusinthidwa odwala achikulire amagwirizana ndi kuchepetsa mphamvu kagayidwe moksodinina, komanso bioavailability ake apamwamba. Chifukwa chosowa maphunziro pharmacokinetic ali osavomerezeka ntchito mankhwala odwala wachikulire.

Mankhwala "Fiziotenz" Malangizo Ntchito

Umboni kuti miyala ayenera kumwedwa pakamwa, kaya mowa chakudya. Childs, mankhwala ntchito koyamba tsiku mlingo wa 200 mcg. The pazipita umodzi kuchuluka kwa mankhwala sayenera upambana 400 micrograms kuchuluka tsiku anagawa masitepe awiri - 600 micrograms. Odwala zolimbitsa bwino aakulu mtima amene ali pa hemodialysis, Ndi bwino kutenga 200 micrograms pa tsiku imatanthauza. Ndi zabwino kulolerana kuchuluka kwa mankhwala akhoza ziwonjezeke kawiri.

ambiri osokoneza

Ngati ntchito kwambiri zizindikiro zosiyanasiyana zoipa kumachitika mankhwala. Choncho, mapiritsi kwa "Fiziotenz" kuthamanga (ndemanga amaganiza kuti iwo) lingachititse mutu, tulo, sedation. Pamene mlingo wopyola kuthamanga mwina kusiya kwambiri, kuyamba kupweteka epigastric anaona xerostomia, bradycardia, kusanza, kutopa, kuchuluka kufooka, chizungulire. Komanso, odwala akhoza kukhala nkhawa hyperglycemia, tachycardia, ndi kufupika kuwonjezeka kuthamanga.

ZINGATHANDIZE zenizeni zomwe zochizira zizindikiro cha mankhwala osokoneza bongo. Ngati hypotension alowe dopamine ndi kuonjezera zili madzimadzi mu thupi. Zizindikiro za bradycardia n'zotheka kuti asiye ntchito atropine. Mu ambiri osokoneza kuchepetsa kapena kuthetsa paradoxical wolumikizira oopsa azimwa muzikangana alpha-adrenoceptor.

Mwanjira mankhwala

Kuphatikiza mankhwala sikuti n'kofunika kwambiri chifukwa. Komabe, pamene kulandira mankhwala awiri kapena kuposa mwina chifooke kapena kulimbitsa zochita mangawawo. Mbali yoyamba, mankhwala sudzapereka chifukwa ankayembekezera zinthu wachiwiri, pali chiopsezo cha mankhwala osokoneza bongo, ndipo ngakhale poizoni.

Choncho, pamene ntchito mankhwala antihypertensive (okodzetsa thiazide, calcium blockers njira pang'onopang'ono) ndi medicament "Fiziotenz" (ndemanga kuchenjeza za izi) angathe hypotensive zowonjezera kwenikweni. Munthawi yomweyo chithandizo ndi antidepressant tricyclic Sachita mphamvu ya mankhwala chapakati protivopertenzivnyh, ndipo sayenera kugwiritsidwa ntchito pamodzi ndi mankhwala "Fiziotenz".

Komanso, chida amalola kusintha ntchito chidziwitso odwala chokumana ndi kutenga mankhwala "Lorazepam". Ntchito pamodzi ndi benzodiazepines zikhoza kuzikonzanso sedation. Poika mankhwala "Digoxin", "glibenclamide", "hydrochlorothiazide" palibe mogwirizana pharmacokinetic.

Ntchito pa mimba

mankhwala osiyanasiyana kusokoneza mwana wosabadwayo, kapena mwana wosabadwayo, kutsogolera zina za makhalidwe oipa a mwanayo. Monga zigawo za mankhwala otengedwa mkaka mayi, ukhoza kugwera mu thupi ana kanthu. Choncho, pa mimba ndi mkaka wa m'mawere, m'pofunika kutenga mankhwala mosamala kwambiri.

Yotero - ndi mankhwala "Fiziotenz". udindo wake umakhala atakambirana ndi katswiri, bwinobwino phindu kuthekera kwa amayi ndi kupha mwanayo. Popeza pophika yogwira akudutsa mu mkaka wa m'mawere pa kudya khanda ayenera kusiya ntchito yake kapena kusiya kuyamwitsa.

maphunziro Experimental imachitika pa zinyama, mwachindunji kapena mozungulira zotsatira za mankhwala pa mimba, yoopsa (embryonic) kapena chitukuko postnatal kuti sakudziwika.

mbali zotsatira

Ngati mankhwala ambiri, mapilisi "Fiziotenz" (ndemanga zimasonyeza kuti izi) amayambitsa zotsatira zoipa m'thupi. Izi zimachitikira pamene inu ntchito ndalama pazipita kwa nthawi yaitali ndipo hypersensitive kwa pophika yogwira.

Mantha dongosolo ndi kugwiritsa ntchito mankhwala amachitira mutu, tulo kapena kugona, chizungulire. Zizindikiro zimenezi zimawoneka kawirikawiri zokwanira. Pa gawo la mtima ndi mtima dongosolo zosiyanasiyana chokhwima zimachitika nthawi zina, izo ziri kuwonetseredwa ndi dontho lakuthwa mu kuthamanga, orthostatic hypotension. Komanso, odwala pambuyo makonzedwe zinachitikira youma pakamwa, nseru, iwo zingaoneke ngati zochita dermatologic angioedema, pruritus kapena totupa. Ngati pali mbali zotsatira za mankhwala sayenera anasiya, zizindikiro zoipa pambuyo masabata atatu a ntchito, iwo amakhala kutha. Komabe, kufunsa katswiri chikufunikabe.

contraindications

Palibe mankhwala "Fiziotenz" angathe kumwedwa milandu onse. Reviews madokotala kunena kuti tikulimbikitsidwa kuti kumwa mankhwala pa:

• bradycardia (kugunda kwa mtima Ine 50 kumenyedwa pamphindi);
• SSS;
• cholowa galactose malabsorption kapena tsankho (shuga)
• Lactase akusowa;
• kuchuluka kudziwa njira chigawo;
• ndi ana osakwana zaka ambiri.

CHENJEZO Kwalamulidwa mankhwala gawo osachiritsika kwambiri kapena aimpso kulephera, odwala amene hemodialysis, zoopsa aakulu chiwindi.

Miyala "Fiziotenz": zikuonetsa ntchito, ndemanga, malangizo apadera

Pulayimale matenda, limene madokotala mankhwala ndi oopsa. Ziyenera adzanyamula kukumbukira kuti pamene mankhwala ayenera kuchita polojekiti mwadongosolo boma la magazi, ECG ndiponso kugunda kwa mtima. Ngati mukufuna kuletsa mankhwala, ndiye izi zichitike pang'onopang'ono.

mankhwala si kusokoneza kuthekera kuyendetsa ndi njira zina zamayendedwe. Komabe, chiphunzitso "Fiziotenz" (umboni mtima kuloza kwa iwo) chofunika kutenga mosamala chifukwa zingachititse chizungulire ndipo kusinza. Zimenezi ayenera kuwaganizira anthu a woopsawo, napempha ndende zonse zochitika.

zinthu yosungirako, analogs ndi mtengo

Mapiritsi zisungidwe malo kumene ana sangafikire. Phunziro kwa malamulo a yosungirako (kutentha kwa madigiri 25 C, wouma mdima place) mankhwala sadzatayikiridwa katundu wawo pharmacological kwa zaka ziwiri. Kugula mankhwala "Fiziotenz" (ndemanga titsimikizire kuti) kuli kotheka pa mankhwala mu pharmacies. Price ma CD a mapiritsi (0.2 mg) ndi 275 rubles. Ngati mankhwala pa mankhwala pazifukwa zina sanali, m'pofunika kuyang'ana anzake: "Cynthia," "Moksoniteks", "Moxonidine", "Moksogammu".

Reviews kukonzekera "Fiziotenz"

odwala ambiri amalankhula za mankhwala monga njira wogwira mtima wa khalidwe. Anthu amanena kuti cholanda kwa zaka, mankhwala Sachita magazi ndi zabwino, ndi zotsatira palibe mbali. Ena amati zolakwa za miyala mkulu mtengo "Fiziotenz". Reviews zikuonetsa ngakhale wabwino ndi njira zina mankhwala hypertensive.