Mankhwala "Hydroxyzine": malangizo ntchito, analogs ndi ndemanga

Diphenylmethane opangidwa kuchokera kwa thunthu ndi njira "Hydroxyzine". Ogwiritsa ntchito limanena kuti chinthu ndi choyera bwino ufa, sungunuka m'madzi ndi odorless. magalamu 374,9 pa Mfuko ndi kulemera maselo pawiri lapansi.

Clinico-pharmacological gulu

Mankhwala ali sedative, anxiolytic kwenikweni. Izi akufotokoza mmene ochepetsera pa ntchito zina nyumba subcortical wa chapakati mantha dongosolo komanso kutsekereza kanthu chapakati H_1-histamine ndi mamita-cholinergic zolandilira.

"Hydroxyzine" analogues mankhwala ndi sedation kutchulidwa ndi ntchito wofatsa anxiolytic. Ndi wapaulendoyo nzeru chidziwitso, bwino chidwi ndi kukumbukira. Zamatsenga kudalira komanso mumapezeka zimachokeradi pambuyo ntchito yaitali syndrome si anati. Kumaonekeranso anticholinergic, a antihistamine, kanthu antispasmodic. "Hydroxyzine" relieves spasms minofu yosalala, potero kupangitsa bronchodilatory ndi zotsatira analgesic, ali kanthu antiemetic ndi zolimbitsa ochepetsera kugwira ntchito pa katulutsidwe muzituluka. . Sikofunika, dermatitis, chikanga, kuyabwa, etc. amachepetsa pa mankhwala amatanthauza "Atarax" (hydroxyzine - yogwira mankhwala).
Guide limanena kuti sedation zimatheka, zambiri mwa mphindi 10 kuti 45 pambuyo ingestion (malingana ndi mtundu wa mankhwala), odana histamine - ola limodzi pambuyo ingestion. Mu odwala matenda a chiwindi, zimakhudzanso antihistaminic tingayembekezere pasanathe maola 96.

Unalibe mutagenic ndi carcinogenic kanthu mankhwala.

Pharmacokinetics

Pamene ingested mankhwala mofulumira odzipereka kwa mundawo m'mimba, C_max kumeneko maola awiri. Kukonzekera "Hydroxyzine" kudutsa nsengwa ndi magazi ubongo chotchinga (mlingo wa ndende mu zimakhala yoopsa kwambiri kuposa zimakhala akuchikazi). Mu ndondomeko ya kwa chiwindi kagayidwe anapanga cetirizine - ndi metabolite lalikulu. Ubwino T_1 / 2 kaya zaka wodwala ndipo kungakhale 7 maola ana zaka 2-10, maola 20 akuluakulu, maola 29 okalamba ndi okalamba; odwala ndi chiwindi matenda akhoza ziwonjezeke kwa maola 37. Kucotsa ikuchitika kwa gawo lalikulu ndi impso (0.8% mu maonekedwe ake original).

zikuonetsa

"Hydroxyzine Hydrochloride" ntchito:

• kuthetsa nkhawa ndi hyperexcitability ya ubongo;
• pa achire ku anthu akuvutika kudalira mowa;
• achire mankhwala a matenda psychoneurotic;
• monga mbali ya chithandizo mabuku mu nthawi postoperative patapita kuvulala;
• premedication;
• kuchepetsa kupanikizika mkati, nkhawa zowombetsa mkota, njira kusintha kuchira, mu mankhwala a matenda zokhudza zonse;
• kuthetsa zizindikiro za chikanga, kuyabwa dermatosis, urticaria, atopic dermatitis;
• kuchitapo kanthu antiemetic anasonyeza.

Contraindications mankhwala "Hydroxyzine Canon"

Reviews madokotala akusonyeza kuti mankhwala ali osavomerezeka kulandira:

• odwala matenda khungu;
• Prostate hypertrophy (Prostate);
• odwala amene ali kulalikira mwakhama kulanda;
• odwala myasthenia gravis;
• odwala amene anapezeka aimpso ndi kwa chiwindi kulephera;
• odwala ndi maganizo.

mankhwala ali contraindicated mu:

• amayi apakati;
• odwala porphyria;
• nthawi yoyamwitsa (nthawi ya mankhwala ayenera kusiya mkaka yoyamwitsa mayi);
• matupi awo sagwirizana mawonetseredwe kwa apanga pophika (monga milandu kumene kale amalembedwa hypersensitivity ena otumphukira cetirizine, aminophylline Piperazine kapena ethylene diamine);
• pa ntchito ndi yobereka.

About mavuto

Odwala akudwala kugona, kusangalala ambiri kufooka, chizungulire ndi mutu chiyambi cha mankhwala "Hydroxyzine". Reviews odwala mankhwala wothandizila, kuti zotsatira zotsatirazi mbali:

• thupi lawo siligwirizana, palpitations, nseru;
• mkodzo posungira, ndi kudzimbidwa;
• dryness wa zimagwira ntchito zosiyanasiyana zooneka mucous, kuchuluka thukuta;
• amaona masomphenya (mwina kuphwanya malawi);
• kutsitsa magazi, kuchuluka ntchito chiwindi enzyme;
• angakhale nayo bronchospasm.

osowa mawonekedwe khunyu, kugwedeza ndi disorientation, ataxia, paradoxical kukondoweza ndi kuchuluka ntchito galimoto kugwiritsa ntchito zipangizo.

ambiri osokoneza

Patsogolo otchedwa gag reflex kapena m'mimba kusamba ndi ambiri osokoneza wa mankhwala "Hydroxyzine". Malangizo ntchito imatiuza kuti nthawi zina m'pofunika polojekiti ntchito wodwalayo yofunika kwambiri oyamba benzoate sodium, tiyi kapena khofi, norepinephrine, ndipo ngakhale mmalo magazi, akutsatiridwa zinthu zonse zofunika kwambiri uziyenda bwino za thupi. ZINGATHANDIZE Specific chida ali, hemodialysis sayesedwa wolungama.

Nthawi zambiri, zotsatira ndi kusintha kapena matenda awo kutha pambuyo mlingo tsiku la kuunikanso.

Mlingo

mankhwala chikuyendetsedwera kuwauza kapena jekeseni mu mnofu. Mlingo zimadalira nosologies, m'badwo wa mtima ndi mawonekedwe imene mankhwala adzamasulidwa "Hydroxyzine".

Malangizo ntchito zikusonyeza kuti symptomatic mankhwala syndrome nkhawa, wamkulu akulimbikitsidwa kudya a mg ndi 25 100 wa chinthu constituent masana. The zambiri ntchito mlingo wa 12,5 mg wa m'mawa ndi pa nkhomaliro ndi 25 - madzulo.
Mu ubwana, preoperatively ntchito 1 mg pa kilogalamu ya kulemera kwa thupi pa tsiku Madzulo ndi mphindi 60 pamaso ndondomeko.

Chifukwa cha premedication chikuyendetsedwera akuluakulu "Hydroxyzine" pa mlingo wa 50-200 mg wa mankhwala kuwauza kapena mu mawonekedwe a jekeseni mu mnofu wa 1.5-2.5 mg wa pa makilogalamu kulemera mtima kutumikiridwa ola limodzi pamaso opaleshoni.

Chifukwa cha thandizo la kuyabwa mlingo ogwira mtima ndi ku 25 100 mg mu 3-4 Mlingo wogawanika.

Ana kwa zaka chaka chimodzi 6 mlingo si upambana 1-2.5 mg wa pa makilogalamu thupi patsiku pa mlingo osiyanasiyana.

Mofanana dosing chakudya kwa ana osaposa zaka 6 amagwira ntchito 1-2 mg wa pa makilogalamu thupi masana.

Zolemba malire tsiku mlingo ankaona kuti 300 mg. Zolemba malire umodzi mlingo - 200 mg.

Okalamba mwambo wa mankhwala tikulimbikitsidwa pa theka mlingo.

Chiwindi ndi kulephera impso afunika kulangiza za mlingo wa mankhwala "Hydroxyzine".

Guide limatichenjeza kuti tikwaniritse pazipita achire zotsatira njira mofulumira chikuyendetsedwera intramuscularly akuya 50-100 mg wa pa mlingo umodzi. Yovomereza njira makonzedwe mankhwala kwa maola 4-6.

Mu maganizo, mankhwala umagwiritsidwa ntchito mlingo wa 300 mg masiku. Kutalika kwa mankhwala masabata 4.

Mu nkhani ya mawonetseredwe mavuto monga kufooka, kugona, sasiya mwa masiku angapo, mlingo ayenera kuchepetsedwa.

kusamala

Ngakhale kumayambiriro "Hydroxyzine" ndi "zikuwonjezereka masiku ano" lolimba sakhala ogwira.

Mankhwala kumakhudza ikuthandizira pa zotsatira sedative wa chomwa mankhwalawa analgesics zino, mowa zakumwa, asamakhale ndi nkhawa, barbiturates, mankhwala ntchito ndi cholinga cha mankhwala zachinyengo ndi ena kuti nkhawa CNS ntchito.

Osavomerezeka ntchito anzake a thunthu kapena holinoblokatorami ndi Mao zoletsa.

Pamene pamodzi ndi njira kutenga phenytoin anticonvulsant zotsatira amachepetsa ku phwando ya masika.

Osafunika munthawi yomweyo kugwiritsa ntchito mankhwala ndi blockers cholinesterase.

A chifukwa kuwonjezera madzi ambiri mankhwala ukhalebe tanthauzo lake ndi zoletsa wa michere chiwindi.

Munthawi yomweyo chithandizo ndi nthumwi zomwe ziletsa ntchito ya CNS, kapena ndi holinoblokatorami amafuna mlingo kusintha.

Mosamala ayenera mankhwala kwa odwala ali ndi propensity kwa fibrillation kapena kugwiritsa antiarrhythmics, komanso odwala amene ali predisposed kuti mawonetseredwe convulsive. chithandizocho ndi contraindication kuti kumwa mowa. Ngati ndi kotheka, khalidwe mayesero pa chifuwa phwando "Hydroxyzine" kuletsa masiku 5 pamaso kuona yokonzedweratu. Tiyenera kusamala pamene ntchito mankhwala ndi kulamulira galimoto nthawi madalaivala ndi odwala, kudzinenera kuti amafuna mkulu ndende.

Ziyenera adzanyamula kukumbukira kuti ntchito injectables ndi Zimatheka jekeseni mu mnofu. Subcutaneous jekeseni wa galimoto kapena malowedwe a yotsirizira mu zotengera lalikulu kungawononge minofu.

Therapy chida ichi chikhonza vyzyvavt zotsatira zabodza mayeso pokha.

Terms ndi zinthu ntchito ndi kusunga

M'pofunika pamaso lamulo la mankhwala mankhwala "Hydroxyzine".

Malangizo ntchito akunena kuti njira m'kamwa mankhwala si kusungidwa kwa zaka zoposa 5.

"Hydroxyzine". umboni

Ana, kugwiritsa ntchito ndalama pansi ofuntha, yafupika zinthu mosiyana kumathandiza mwana wanu kukhala wolimba, sukulu tcheru, kumatha mmene alili. Pa nthawi yomweyo mankhwalawa mankhwala "Atarax" ( "Hydroxyzine") malangizo ntchito limatitsimikizira kuti ntchito ndi umoyo wa mwana kukhala yemweyo. Zotsatira zake zoyipa n'zochepa.

Malinga ndi mawu a odwala, kugwiritsa ntchito zina "Hydroxyzine" (analogues ya mankhwala), ndizoonekeratu kuti iye ndi bata ndi azidzidalira Pamlingo kuposa mankhwala ena ambiri. Mantha oukira ndi tulo mankhwala umalimbikitsa bwino tulo ndi tulo phokoso. Komabe, kuchotsa mankhwala masiku oyamba a kuphetsa ndondomeko tulo, koma mfundo zotsatira za mankhwala ndi lolimbikitsa kwambiri.

Mtengo wa mankhwala

Kugula mankhwala "Hydroxyzine" Akhristu, monga gawo limene lili hydroxyzine, kungakhale mankhwala pa mankhwala. Price ndi 270-300 rubles pa miyala 25 25 mg.

"Hydroxyzine". Mau ofanana

Mau ofanana a "Hydroxyzine" ndi: "Hydroxyzine Canon", "Atarax", "Masmoram", "Ateraks", "Hydroxyzine", "Hydroxyzine Hydrochloride", "Alamon", "Duraks".