"Glewe" mankhwala. Malangizo ntchito

Mankhwala "Glewe" ndi mbali ya gulu la otchedwa fluoroquinolones. Izi wothandizila antibacterial amene anatchula ntchito antimicrobial ndi amadziŵika ndi sipekitiramu yotakata kanthu. Waukulu yogwira pophika mankhwala ndi levofloxacin. Iwo amatha kutsekereza DNA gyrase (enzyme, kumene kutumikiridwa mu chatsekedwa supercoils zoipa DNA), kuswa ndi udzaphwanya supercoiling ya DNA kaphatikizidwe ndi chifukwa kusintha kwakukulu mu dongosolo la tizilombo ndi.

Matenda amene amayamba ndi tizilombo yaying'ono-zamoyo tcheru mankhwala "Glewe" malangizo Buku lofotokoza zikuonetsa ntchito. Zimenezi zingakhale matenda ENT (mwachitsanzo, pachimake sinusitis), impso ndi kapepala mkodzo (monga matenda ovuta wopepuka, monga pyelonephritis pachimake) m'munsi kupuma matenda thirakiti (chibayo dera yotengedwa, exacerbation wa chifuwa).

Komanso, mankhwala akusonyeza kuti Prostate ndi matenda ena opatsirana a ziwalo zoberekera, minofu zofewa ndi matenda khungu (mwachitsanzo, abscess, zamafinya zinangoti atheroma, furunculosis). Pamene intraabdominal (mwa kulankhula kwina, intraabdominal) matenda opha tizilombo "Glewe" ntchito limodzi ndi mankhwala kuti kanthu pa microflora anaerobic.

Mukhozanso mankhwala "Glewe" mu mawonekedwe a mapiritsi a 250 ndi 500 mg. Pa phwando zikutanthauza mofulumira odzipereka, ndi chakudya ndi pafupifupi ziribe mphamvu pa chokwanira ndi liwiro yanyumba mankhwala "Glewe". Malangizo ntchito limasonyeza kuti mankhwala likulowerera bwino mu zimakhala ndi ziwalo. Mankhwalawa mbali yaing'ono ya mankhwala akhoza oxidized. mankhwala ndi excreted makamaka ndi impsozo.

Mankhwala mavuto ambiri mbali ku machitidwe osiyanasiyana a thupi. Mwachitsanzo, dongosolo m'mimba zingachititse kusanza, kutsekula m'mimba, kupweteka m'mimba, kunyansidwa, kusafuna kudya ndi kudzimbidwa, kuwonjezeka transaminases chiwindi, matenda a chiwindi, hyperbilirubinemia, Chotupa chija, appetitapsevdomembranozny enterocolitis.

Mu dongosolo mtima, ndi matenda otsatirawa - mtima kugwa, kutsitsa magazi, kutalikitsa ndi imeneyi QT (magetsi mtima systole) - ndi chiopsezo arrhythmia, tachycardia, mu nthawi zina - matenda fibrillation.

Dongosolo endocrine pa phwando maantibayotiki "Glewe" malangizo ntchito kumaphatikizapo zotsatira zotsatirazi mbali - hypoglycemia, manjenje, thukuta, kuchuluka kudya.

Kuyambira wamanjenje dongosolo - onse chapakati ndi zotumphukira - zotheka chizungulire ndi mutu, kutopa, kugona zipolowe, nkhawa ndi mantha, kuyerekezera zinthu m'maganizo, maganizo, wakhunyu khunyu. Pa mphamvu , mankhwala ndi chokhoza kusonkhezera - akhale ndi mkhutu kumva, kuona, chogwirika, gustatory, ndi olfactory tilinazo.

Pakuti kachitidwe ka minofu ndi mafupa pa mankhwala "Glewe" malangizo Buku limafotokoza zotsatirazi mavuto obwera - minofu kufooka, arthralgia, myalgia, tendonitis (tendon kutupa), tendon chophukacho. Hypercreatininemia, pachimake aimpso kulephera, nephritis interstitial ndi mavuto kwa dongosolo mkodzo.

Mu dongosolo hematopoietic angaoneke kuyan'anila monga kuchepa magazi hemolytic, eosinophilia, leukopenia, agranulocytosis, neutropenia, pancytopenia, thrombocytopenia ntchito maantibayotiki "Glewe". Malangizo Limanenanso kuti n'zotheka thupi lawo siligwirizana, exacerbation wa porphyria, chitukuko cha superinfection, Malungo yatsoka kauntala.

Pakati contraindications ndi - kudziwa mankhwala, khunyu, mimba ndi mkaka wa m'mawere, ana osakwana zaka 18, tendon kuwonongeka mankhwala koyambirira ndi mankhwala.

Chenjezo ayenera kugwiritsidwa ntchito mankhwala odwala okalamba ndiponso ndi kuchepekedwa shuga-6-mankwala dehydrogenase. View wa kuchuluka kwa mavuto, musatenge mankhwala "Glewe" paokha popanda kufunsa dokotala.