Conjugated linoleic asidi: ntchito ndi zotsatira zake zoyipa. Conjugated linoleic asidi: Ndemanga

Posachedwapa mungathe kumva zambiri za ubwino zowonjezera zakudya, amene ali m'gulu la asidi conjugated linoleic. linoleic, ndipo ngakhale zambiri conjugated Kodi anthu ochepa mukudziwa. Layman kwambiri kapena sichidziwika bwino mawu umagwirira ndi mankhwala "asidi". Kugula mankhwala ndi mankhwala okhala pophika izi, ambiri a ife Tikutsatira mfundo malangizo ndipo amayembekezera kuti zotsatira zamatsenga. Yesetsani kumvetsa zimene tingayembekezere kwa mankhwala.

asidi linoleic

Kuti moyo wathanzi ndi chamoyo yachibadwa ziwalo zonse anthu n'kofunika kwambiri kuti thupi la mafuta zidulo zofunika, monga linoleic. Ndi liniya unyolo wa maatomu mpweya omwe kuchuluka mayiko biochemists. Pakati pa 9 ndi 10, ndi pakati pa maatomu 12 ndi 13 kuti muli substituents kulankhulana. carbons makuponi kuŵapatulanya, kuteteza kugwirizana izi kusokoneza mzake kuposa katundu wa thunthu atsimikiziridwa. Conjugated asidi linoleic akhoza zopezera monga mungafike mu kutembenuka njira zophweka asidi linoleic kuti stearic. Onse atatu ndi yofunika kwambiri kagayidwe anthu. Popanda zidulo mafuta, makamaka linoleic, mu thupi linaphwanya njira kagayidwe kachakudya zowawa dongosolo mtima, magazi, atherosclerosis akufotokozera ndi worsens mphamvu, zimakhala onse. Ambiri asidi linoleic ndi pa structuring wa nembanemba maselo thupi. Nkofunika choncho kudya zakudya zokhala ndi izo.

ndi conjugated asidi linoleic Kodi

Pa nkhani imeneyi, isomer-ziwanga kusintha malo awo. Mmodzi wa iwo ili pakati pa 6 ndi carbons 7, ndi zina pakati pa 8 ndi 9. Tsambali pafupi zimawathandiza kusonkhezera wina ndi mnzake, komanso umodzi ufulu chomangira mpweya maatomu, ataima pakati pawo. Kusiyana wachiwiri awiri zokhudzana zidulo malo kulumikizana substituents wachibale ndege ya unyolo. Mu linoleic yosavuta ndi CIS-mawonekedwe, ndiye mbali imodzi, ndipo pangakhale conjugated Trans-mawonekedwe, chimene chiri chosiyana. Ndiyamika izi kusiyana zinkaoneka zazing'ono conjugated linoleic asidi amapeza katundu watsopano. Kwenikweni, amatha kuchita ntchito awiri - kupondereza ntchito ya onse mafuta m'magazi transporter mu maselo, lipoprotein lipase, ndipo nthawi yomweyo kumapangitsanso azingokhala alipo thupi mafuta, pamene linoleic wamba M'malo mwake, zimathandiza kuti pakhale mafuta. Kusiyana kwina zokopa n'chakuti asidi linoleic mwapadera amalimbikitsa mafuta chiwopsezo kuti zochita makutidwe ndi okosijeni, ndi conjugated izo limakhazikitsa.

Kutsegula kwa sayansi American

Ngakhale luso lamakono, conjugated linoleic asidi (CLA) chatsegulidwa posachedwapa. Mu zaka 1979-1980 gulu la asayansi ku University of Texas imachitika maphunziro ambiri a pa zotsatira za zakudya zosiyanasiyana pa moyo wa chamoyo. Michael Peyriz, yemwe anali wothandizira, anaona kuti soseji zapadera njira kumathandiza masinthidwe mu DNA a maselo minofu nyama. Anapeza kuti chuma ichi apeza chinthu nyama. zofufuza Komanso anatsegula ndi zina zothandiza katundu wa zinthu zatsopano, makamaka kuthekera ziletsa kukula zotupa khansa. Izi anatumikira monga kutsogolera amphamvu kuphunzira njira amuzolengedwa kumatheka ntchito asidi conjugated linoleic.

zothandiza zimatha

Pa nthawi imeneyi, maphunziro anasonyeza kuti conjugated linoleic asidi (CLA) amatha:

• imathandizira kagayidwe thupi;
• chingatithandize kukhalabe minofu misa;
• m'munsi mafuta m'thupi;
• kuchepetsa kufala kwa matenda a shuga ndi kukana insulin;
• kusintha chitetezo chokwanira;
• kuthandiza m'njira pa kuchepetsa wa milandu chakudya ziwengo.

Kukonzekera CLA ziletsa ndondomeko ya kudzikundikira mafuta, makamaka peritoneum (choipidwa). Mtundu wa mafuta kuti akhoza analanda ziwiya chiwindi, mtima ndi magazi, ndi woopsa kwambiri ndipo nthawi zambiri kumayambitsa mtima, sitiroko, thrombosis, ndiponso mavuto ena. CLA kumawonjezera tilinazo ena a minofu ndi insulin, kotero mafuta komanso shuga kunadetsa kudutsa nembanemba ndi mwamsanga "mu malo". Chifukwa, kuchuluka kwa mafuta ndi wotsikirapo ndi minofu misa umachuluka.

Laboratory maphunziro ndi zatsopano

Ngakhale kuti ambiri katundu kozizwitsa conjugated linoleic asidi, ndemanga ya madokotala ndi akatswiri ndi osokoneza za izo. Ichi ndi chifukwa chakuti panthawi imeneyi ntchito mankhwala, zatsopano ambiri akhala akuchita pa nyama. Mwachitsanzo, mu makoswe tsiku kudyetsa nyama wokazinga, kwambiri oletsedwa chotupa mapangidwe ndondomeko. N'zoona kuti sizingatheke kuti tipeze zimene siteji zimachitika - kumayambiriro, mwapang'onopang'ono kapena osachiritsika pamene khansara wayamba metastasize. Pali maganizo oti mankhwala ntchito pa onse atatu. Komanso, makoswe ndi nkhuku CLA kwambiri kumalimbitsa chitetezo cha m'thupi, monga nyama kuwonjezera amalimbikitsa kukula yogwira. gulu lina la nyama - akalulu ndi hamsters - CLA kumathandiza kuchepetsa wa mitsempha chifukwa mipukutuyi atherosclerotic. Pagulu, zatsopano ofanana siinkachitidwa, motero mfundo yotsimikizika ndi isanakwane.

Zatsopano pa kuwonda

Mungapeze mfundo kwakukulu amathandiza kuonda conjugated linoleic acid. Ndemanga za anthu amene ayesa kanthu ake pa iye mwini, komanso osokonezeka. Ena anasangalala, ena tingati si anaona. Mu 2000, Swedish asayansi linatulutsa zotsatira za kafukufuku wawo awo ndi gulu la anthu ongodzipereka, hudevshih ntchito CLA. Onse a iwo masiku 64 yochuluka conjugate asidi 3.4g. Sanataye aliyense ophunzira wina. Mu chaka chomwecho, akatswiri ena palokha afalitsa zotulukapo zotsutsana za zatsopano kuchitidwa gulu lina la anthu wonenepa. Malinga ndi kafukufuku awa, kuchepa thupi unkachitika pa anthu amene kukonzekera CLA. kuyesera wina kuchitikira asayansi Norway. Iwo anagawana ophunzira mu kuyesera m'magulu anayi, lililonse ndi kudya tsiku la CLA anali 1.7 G 3.4 G 5.1 ndi 6.8. kulemera kuchepa anali kokha mu magulu awiri otsiriza, amene ankadya mlingo waukulu wa mankhwala.

Zokumana Nazo ndi mfundo za Michael Peyriza

Kodi anthu, ndipo osati pa nyama conjugated asidi linoleic monga njira kuwonda? maphunziro anali kuchitidwa moyanjana chachikulu. Nawo amuna ndi akazi a misinkhu tonse a magulu osiyanasiyana. Michael Peyriz, ndi anatulukira chinthu nawo zimenezo gulu la anthu akunenepa (71 ongodzipereka). Onse ali mkati miyezi 2 kutenga magalamu 3.4 mankhwala tsiku ndi kutsatira zakudya zomwe amakonda chakudya zimathandiza kuti kunenepa. Gulu ulamuliro wonenepa mwa zakudya yekha popanda mankhwala. gulu Project makamaka wonenepa, koma kumapeto kwa zakudya kachiwiri anayamba kum'tenga, natenga mankhwala okha kumangidwa minofu misa, pamene gulu kulamulira kuchuluka kukula kwa mafuta m'thupi kachiwiri. deta yidzalola asayansi kuti mawu CLA osati amachepetsa kukula kwa mafuta, mmene ambiri amalephera zina kuonjezera iwo. kuyesera anasonyeza kuti mankhwala akhoza patsogolo insulin katulutsidwe odwala ndi mtundu shuga II ndi kuchepetsa zizindikiro kachulukidwe shuga magazi. Zotsatira anali anati m'ma kulandilidwa ndi mphambu ziwili ongodzipereka mayeso.

Mankhwala ndi CLA

Ambiri amachita chidwi ndi funso asidi conjugated linoleic imene mankhwala lili. Iripano ananenera mu pharmacies ndi masitolo masewera bioactive zowonjezera ndi pophika izi:

1. "Linofit". Kenaka accommodates makapisozi 60, aliyense asidi 800 mg. Mtengo msika Russian kuyambira mu 1500 rubles. Pamodzi ndi CLA mu makapisozi lili ayodini ndi vitamini B6, amene kwambiri kumawonjezera katundu wofunika kwa enaake zakudya.
2. "Reduxine kuwala." Yopangidwa phukusi 30, 90, 120 ndi 180 makapisozi uliwonse uli 500 mg wa conjugate acid ndi vitamini E. Price ku rubles 1000 ndi 2720 (malingana ndi kuchuluka kwa makapisozi).
3. "Chocolate ndi moyo." Atanyamula 10 limapangidwa phukusi ndi ufa CLA kumene kumwa ndi kukonzedwa. Price ku rubles 300.

Palinso Akhristu achilendo: Zerofat, CLA, CLAextrim ndi ena. Pafupifupi mtengo wa madola 15.

zachilengedwe

Pali zambiri ndithu zowonjezera zakudya kuchokera opanga osiyana, imene chigawo chachikulu ndi conjugated linoleic acid. ndemanga kasitomala zosiyanasiyana komanso zotsatira za kafukufuku wa sayansi. Pali anthu ambiri amene anaona ndi zotsatira zabwino. Pa nthawi yomweyo ambiri a iwo amene aona kuchepetsa kulemera ndipo anali ochepa. Kuwonjezera zowonjezera zakudya, CLA chikupezeka mu gulu lalikulu la mankhwala achilengedwe, kotero kuti akhoza kudyedwa tsiku ndi tsiku popanda malamulo alionse. Anasonyeza tebulo ziwerengero mkaka, nyama ndi mazira ndi nyama anauka pa chakudya achilengedwe.

contraindications

Samaoneka ndi ntchito wololera katundu pamwamba chifukwa zochita chokhwima kwa thupi (kupatula chitetezo chokwanira munthu mu anthu). Pa ntchito mankhwala omwe munali conjugated asidi linoleic, mavuto mwatsoka zimachitika. Mwachitsanzo, ena makasitomala amene amagwiritsa ntchito zowonjezera zakudya ndi CLA anati akuchuluka zotupa analipo, kulephera mu m'mimba thirakiti, totupa, nseru. Anthu 47 okha Sweden pa zimenezo pa 60 amene ankachita nawo zimenezo anatha kupereka njira yonse. wotsalawo adachititsidwa amakakamizidwa kupereka chifukwa cha mavuto ena thanzi.