Asidi Phosphatidic. Kaphatikizidwe ndi tanthauzo mu thupi

Amazionera dongosolo mankhwala, asidi phosphatidic ndi phospholipid losavuta.

mankhwala ndi chimodzi mwa zikuluzikulu za phosphoglycerides kagayidwe mu pompo-pompo.

Gulu la zinthu wapatsidwa chidwi mu kuphunzira ntchito chizindikiro cha mankhwala.

Chibwenzi, mpaka kumapeto si bwino ndi maulalo onse kagayidwe zidulo phosphatidic, makamaka, akadali ayankhe funso la limagwirira mgwirizano deta chizindikiro HIV, komanso za kukhalapo zidulo phosphatidic ionophoric katundu.

Kaphatikizidwe wa asidi phosphatidic

Phosphatidic asidi mapangidwe zimakhudza phospholipase D. Gulu la a michere ali ndi udindo kutsogolera mu kaphatikizidwe zidulo phosphatidic. Monga yochepa yaitali mankhwala pawiri, kenako chinthu mchikakamizo fosfogidrolazy hydrolysed kuti diglyceride (by dephosphorylation anachita).

Pamene zimavuta ndi chimodzimodzi enzyme asidi phosphatidic akhoza asandulike diacylglycerol, amene amachita mkombero wa amuzolengedwa zochita activator ntchito ya enzyme mapuloteni kinase C.

Kaphatikizidwe wa asidi phosphatidic zimachitika adipose minofu. ndondomeko akuyamba ndi chiphaso mu adipocytes (adipose maselo minofu) mafuta zidulo kupangidwa mu hydrolysis wa mafuta (makamaka, otsika kwambiri kachulukidwe lipoproteins). Mkati mwa selo, zimavuta ndi glycerol-Tri-mankwala, zidulo mafuta mtima oyamba asidi lysophosphatidic, imene kenako anaumba asidi phosphatidic.

Chilinganizo anapanga therefrom glycerophospholipids phosphoric munali zatsalira zidulo mafuta, glycerol, ndi asafe munali anions.

Meaning asidi phosphatidic

Anapeza kuti asidi phosphatidic ndi otchedwa kusonyeza kugwirizana, kutanthauza anthu amene ntchito ya intermediaries mu kufala kwa mfundo njira ya ma siginalo. Kwenikweni, ulalo zikuluzikulu za kufala kwa zizindikiro mu chomera maselo:

• cytokinin;
• osmotic kuti ali ndi phindu mu chitukuko cha ayankhe ma umenewu nkhawa.

Pa zatsopano izo anawonetsedwa kuti mlingo wa pawiri mu maselo poyera kuti mbewu zamoyo zinthu tizilombo kumawonjezera kwambiri. Zimenezi zimayambitsa:

• Osmotic nkhawa.
• Low kutentha.
• Zotsatira za zosakaniza zina yogwira kukhala chiyambi masamba (phytohormones).

Choncho, Ndizachidziwikire pa nawo asidi phosphatidic ndi metabolites zake zosiyanasiyana zovuta udindo anatengera lake ndi mavuto.

Komanso, amadziwika kuti asidi phosphatidic n'chofunika kuti mayendedwe a mapulotoni zimene ayoni kashiamu mwa nembanemba wa manyuroni ndi ulusi minofu. Choncho, asidi phosphatidic komanso kunenera ntchito ionophore (kusankha: chifukwa ayoni kashiamu ndi mapulotoni).

limagwirira transduction

Ngakhale cholinga asidi phosphatidic anapeza mwachindunji njira (limagwirira) matendawa mbendera akadali kutsutsana ndi kumafuna mfundo.

Komabe palibe angatsutse kuti transduction ikuchitika chifukwa cha luso la asidi phosphatidic, zokhudza kapangidwe ma nembanemba ndi, Kakhungu ndi zonse ntchito michere, ndi naonsO angapezekeko mogwirizana ndi ma mamolekyulu Kakhungu mapuloteni.

Ntchito asidi phosphatidic

Studies ndi antioxidant ntchito opangidwa kuchokera ku asidi phosphatidic, maphunziro mu kuphunzira njira lachitsanzo yokhudza zinthu kwachilengedwenso asonyeza kuti otchedwa phosphatidic asidi mimetics adzalandira antioxidant kuchuluka kwa asilikali a kanthu.

mudziwe mwatsatanetsatane malangizo a kanthu asidi phosphatidic amalola ntchito ndi metabolites ake kupanga zinthu biologically yogwira cholinga kulimbikitsa ntchito ndiponso kupirira kwa maselo.

Timvere mlingo ma, mankhwala amenewa timatsimikiza, koma matenda maselo; mfundo zofunika ndi kuchepetsa chiopsezo cha mavuto mbali.