"Metoprolol": ndemanga, zikuonetsa ntchito, malangizo ndi analogues

N'chifukwa chiyani ndikufunika mankhwala "Metoprolol"? Umboni kukonzekera imeneyi, mitundu zotsatira, zikuchokera, ndi zotsatira zake zoyipa ali anapereka m'munsimu. Ifenso kukuuzani inu chimene chili contra-zizindikiro ndi mankhwala, kodi kumwa mankhwala ayenera kumwedwa ngati pali analogues ena.

The zikuchokera mankhwala ndi kutulutsidwa zikuluzikulu

Mu mawonekedwe zomwe chogulitsidwa mankhwala "Metoprolol"? Umboni kuti mankhwala angapezeke mitundu itatu ya mankhwala. Taonani nkhani ya maonekedwe ndi dongosolo mwatsatanetsatane.

• Mapiritsi. Lili mbali yogwira monga metoprolol tartrate (100, 50 ndi 25 mamiligalamu). Komanso, medicament limapangidwa zigawo wothandiza ndi colloidal silika anhydrous, microcrystalline mapadi, sodium carboxymethylstarch (mtundu A) ndi magnesium stearate. Mu kugulitsa medicament analandira 50, 10, 30, 20 kapena 40 mapiritsi pa paketi.
• Mapiritsi katundu chosunga kutulutsidwa ( "metoprolol succinate") mapiritsi TACHIMATA. Iwo ali ofanana yogwira ndi excipients. Mu pharmacies mankhwala oterewa tingawapeze ndi 30, 20 kapena 10 mapiritsi pa paketi.
• Njira yothetsera jakisoni mtsempha mu ampoules a 5 ml. Mu kugulitsa mankhwala abwera ku katoni bokosi la mbale 10.

The pharmacological katundu wa mankhwala

Kodi zikutanthauzanji mankhwala "Metoprolol"? Zikuonetsa ntchito chida Adzaperekedwa pansipa. Tsopano ine ndikufuna kuti ndikuuzeni inu za zimene ali katundu pharmacological mankhwala.

Anati mankhwala ali wa cardioselective blockers beta-adrenergic. Zilibe kusonyeza Kakhungu ofunika katundu ndipo alibe mkati sympathomimetic ntchito. Komabe, mankhwala yogwira ndi antihypertensive, antiarrhythmic ndi antianginal wothandizira.

The medicament angathe kuchepetsa pafupipafupi kugunda kwa mtima wodwalayo, kuchepetsa m'mnyewa wamtima contractility ndi excitability, wosakwiya AV-conduction ndi kuchepetsa kufunika m'mnyewa wamtima oxygen.

Monga ulamuliro, zotsatira antihypertensive unkachitika odwala pokhapokha masiku khumi ndi anai atakhala mankhwala. The medicament amachepetsa pafupipafupi kuukira ndi tachycardia supraventricular, angina pectoris ndi matenda fibrillation. Chifukwa, yachibadwa mtima kayendedwe ka wodwalayo.

Mapiritsi mochedwa kutulutsidwa ( "metoprolol succinate") ndi mwayi kwambiri pa ochiritsira. Iwo amalola kukhala ndi ndende zonse amafotokozera mwakhama magazi, potero kupereka zabwino achire zotsatira tsiku lonse. Iwo ayenera kukumbukira kuti zochita za "Metoprolol succinate" kumathandiza kuchepetsa chiopsezo bradycardia ndi kufooka, pamlingo wamng'ono, zimakhudza minofu yosalala bronchi ndi.

Pharmacokinetics (mayamwidwe, ndi kupukusa chakudya ndipo excretion wa mankhwala)

Za zikuonetsa ntchito lekarstvai alipo "Metoprolol" analogues mankhwala kufotokoza pansipa, koma tsopano tiyeni tikambirane za makhalidwe pharmacokinetic.

Izi zikutanthauza mofulumira kwambiri ndi pafupifupi kwathunthu (za 95%) ndi odzipereka. Zolemba malire plasma ndende kawirikawiri anafika pambuyo Mphindi 50-110 pambuyo ingestion.

Ntchito yoyamba ya bioavailability mankhwala ndi 50%. Tikuigawa kumawonjezera kwa 70%. Mwa njira, kumwa chakudya kumawonjezera bioavailability wa mankhwala ndi 20-40%. komanso kumawonjezera ngati wodwalayo chiwindi matenda enaake. Kulankhulana ndi mapuloteni pafupifupi 10%.

Anati medicament bwino likulowerera placental ndi magazi ubongo zotchinga. Komanso zedi laling'ono, chionekera ndi mu mkaka wa m'mawere.

mankhwala ndi zimapukusidwa mu chiwindi. Ndipo metabolites ndi ntchito pharmacological. Za 5% ya Mtumiki excreted ndi impso sichinasinthe. Wodwala Therapy ndi ntchito yafupika impso amafuna kuchepetsa kapena zina kukonzedwa mlingo. Komabe, chisokonezo ntchito chiwindi mwina m'mbuyo kagayidwe mankhwala. Pankhaniyi, mlingo ayenera kuchepetsedwa.

Mankhwala "Metoprolol": zikuonetsa ntchito

Pali ndithu mndandanda waukulu wa zinthu pathological imene mankhwala chikuyendetsedwera. Tiyeni tione iwo.

• akathisia, omwe chifukwa cha antipsychotics;
• wolumikizira oopsa wa 1 ndi digiri 2 wolumikizira oopsa (mwina monotherapy, ndi Zikavuta - pamodzi ndi okodzetsa ndi mankhwala ena antihypertensive);
• thyrotoxicosis (gawo chabe la mankhwala ovuta);
• kupewa kuukira angina ndi angina;
• prophylaxis la migraine;
• kuphwanya mungoli mtima (mwachitsanzo, arrhythmia, ndi paroxysmal supraventricular tachycardia, supraventricular tachycardia);
• kuchepetsa chiopsezo pamatenda ndi imfa mwa matenda a mtima ndi inatsekeratu matenda mtsempha wamagazi;
• sekondale kupewa infarction m'mnyewa wamtima ndi pachimake m'mnyewa wamtima infarction;
• mitral vavu prolapse;
• Dilated cardiomyopathy ndi idiopathic;
• giperkinez mtima N'kofunika, hyperkinetic mtima syndrome, matenda a mtima.

Reviews a medicament

Malinga ndi ndemanga za anthu amene munapitako amatchedwa mankhwala, mogwira kupirira ntchito ndi zotsatira zabwino pa mtima. Komabe, tisaiwale odwala ena kuyankha mankhwala si zabwino kwambiri. Monga ulamuliro, ichi ndi chifukwa chakuti iwo ali contraindications ambiri ndi zotsatira zake zoyipa. chakuti odwala akudandaula, fotokozani pansipa pa chiphaso cha ndalama.

Contraindications ntchito mankhwala

Kotero, tsopano inu mukudziwa tanthauzo mankhwala "Metoprolol" (zikuonetsa ntchito imene yatchedwa pamwamba basi). Komabe, mankhwala angapo a contraindications. Njirazi ndi monga:

• Munthu tsankho (i.e. hypersensitivity kwa zigawo yogwira kapena wothandiza);
• atrioventricular chipika 2 ndi digiri 3;
• kamodzi ntchito ndi Mao zoletsa;
• anatseka misewu sinuauricular;
• anasonyeza matenda magazi (zotumphukira);
• nkusani bradycardia (kugunda kwa mtima ngati - osachepera makumi asanu pa mphindi);
• hypoglycemia ndi mawonekedwe labile a shuga;
• odwala nkusani syndrome;
• mtima predisposed kuti bronchospasm (i.e., bronchial mphumu bronchial ayankhe kwambiri);
• kagayidwe kachakudya acidosis;
• hypotension (osakwana 100 mamilimita Hg ..);
• cardiogenic mantha (mankhwala ali osavomerezeka chifukwa odwala matenda a "pachimake m'mnyewa wamtima infarction" kapena amaganiziridwa kuti izo);
• pachimake mtima kulephera, aakulu (2 ndi 3 siteji) ndi uncompensated.

Zoletsa kugwiritsa ntchito mankhwala (phwando mosamala kwambiri)

Kodi milandu ayenera okha kulandira "Metoprolol" mankhwala? Reviews akatswiri amanena kuti mlingo wa medicament kuti yafupika hyperthyroidism ndiko kumayambitsa mbiri siligwirizana, bronchial mphumu, si matupi awo sagwirizana ndi kubanika, psoriasis, pheochromocytoma, matenda a chiwindi, impso ndi (zina), maganizo, myasthenia gravis ndi ochititsa dzanzi ambiri.

Kodi n'zotheka ana mankhwala "Metoprolol"? Kugwiritsa ntchito mankhwala ndi anthu pansi zaka 18 ndikoletsedwa. chiletso A kulandira ndalama chimafikira kwa akazi apakati ndi amayi unamwino. Kulephera kutsatira malangizo awa, pali chiopsezo chachikulu cha bradycardia, hypoglycemia, ndi hypotension mu mwana wakhanda.

Ngati mukufuna mlingo wa mankhwala pa yoyamwitsa, mu nthawi ya mkaka wa m'mawere ayenera anasiya.

Mankhwala "Metoprolol" ndi "Metoprolol succinate": malangizo ntchito

Childs, medicament "metoprolol" kutenga tsiku ndi kuchuluka kwa 100 mg. M'menemo anati buku lagawidwa Mlingo angapo. Pofuna kukwaniritsa bwino achire zotsatira, phwando akhoza chinawonjezeka ndi nthawi 2. Komabe, mlingo pazipita mankhwala sayenera upambana 400 mg.

Pamene kamodzi mtsempha jekeseni kutumikiridwa kwa mg wa 2 mpaka 5 lokonzekera. Pankhaniyi, mlingo pazipita ndi 15-20 mg. Popeza zotsatira anakhumba analola kuti adzathe kulowa mankhwala mankhwala (mphindi 5).

Kuletsa poika mankhwala ayenera pang'onopang'ono. Kawirikawiri zimenezi kwa masiku khumi kuyang'aniridwa mwapadera a dokotala.

Koyamba mlingo wa mankhwala "metoprolol succinate" ndi tachycardia supraventricular, angina pectoris, arrythmia ndi oopsa ndi za 50-100 mg ndi kamodzi pa tsiku. Pamene kukonza mankhwala a infarction m'mnyewa wamtima kulandira medicament mu mlingo wa 200 mg.

Kutalika osachepera chithandizo amatanthauza "metoprolol succinate" ndi miyezi 3. Ngati wodwalayo ndi amawapeza ndi kulephera aakulu mtima, mlingo kusintha payekha. Choyamba, mankhwala atengedwa mu kuchuluka kwa 12,5 mg wa kamodzi tsiku lililonse kwa masabata 2, ndiyeno masiku 14, mlingo kawiri.

Pa kulolerana ndi wabwino wa medicament ndi madyedwe ake pazipita patsiku akhoza kufika 200 mg.

Mankhwalawo. umboni

Iwo akhoza kuwononga thupi mankhwala "Metoprolol"? Reviews kukonzekera izi muli zambiri zomwe pambuyo anavomereza kuti pali zotsatira zoipa. About amene zochitika mu funso?

• Kuyambira wamanjenje dongosolo: minofu kufooka, kutopa, zoopsa maganizo, litsipa, nkhawa, liwiro mosiyanasiyana galimoto ndi maganizo, utachepa tcheru, paresthesia ku malekezero, muzitha kukumbukira kuwonongeka, kugona kapena, Tikawonetsetsa tulo.
• Ku mphamvu: yafupika katulutsidwe wa madzimadzi misozi, utachepa masomphenya, conjunctivitis, ululu ndi youma nembanemba mucous cha maso, kulira m'khutu.
• Cardio-mtima dongosolo: arrhythmia, nkusani bradycardia, angina onyenga, conduction chisokonezo infarction, kutsitsa magazi, kusonyeza vasospasm, orthostatic hypotension, utachepa m'mnyewa wamtima contractility ndi chizungulire.
• Ku dongosolo m'mimba: pakamwa youma, kupweteka m'mimba, kunyansidwa, nthenda ntchito chiwindi, kudzimbidwa, kusanza, kutsekula m'mimba, ndi kusintha kukoma.
• Khungu: kuyabwa, kusintha alopecia, zotupa ankatenthetsa, zidzolo, thukuta, exacerbation wa psoriasis, photodermatosis, exanthema ndi psoriasiform khungu zosiyanasiyana.
• Kupuma dongosolo: kufupika kwa mpweya, kuchulukana m'mphuno, bronchospasm ndi vuto exhaling.
• Pa mbali ya dongosolo endocrine: hypothyroidism, hypoglycemia ndi hyperglycemia.
• Laboratory Yovuta: thrombocytopenia, agranulocytosis, hyperbilirubinemia, leukopenia, ndi okwera chiwindi michere.
• Zotsatira pa mwana wosabadwayo za mkazi wa pakati pa ntchito: intrauterine kukula retardation, bradycardia ndi hypoglycemia.

Komanso, atalandira anati mankhwala ena odwala apakamwa zosayembekezereka wa molumikizana mafupa kapena ululu kumbuyo. amasonyeza yosowa kwambiri anthu kuti iwo pang'ono kuchuluka thupi misa, utachepa libido kapena potency.

malangizo enieni kugwiritsa ntchito mankhwala

Tsopano mankhwala iliyonse mukhoza kugula mankhwala "Metoprolol". Chinsinsi si chofunika. Komabe, odwala kumwa mankhwala ayenera nthawi zonse kuyang'aniridwa ndi dokotala amachitira. Izi ndi zoona makamaka kwa odwala amene amapezeka shuga kapena angina.

Izo mukudziwa kuti ndi kuwonjezeka mlingo (zoposa 200 mg pa tsiku) amachepetsa cardioselective. Pamaso pa mtima kulephera mankhwala ali anayamba pokhapokha gawo malipiro kukufika.

Anthu amene amagwiritsa ntchito magalasi kukhudzana, muyenera kuganizira kuti mu nkhani ya mankhwala, "metoprolol" yafupika yopanga lachrymal madzimadzi.

Nthawi zina masks mankhwala ena zizindikiro za hyperthyroidism. Mu achire izi mwadzidzidzi mankhwala odwala ndi matenda ananena contraindicated, popeza timapitiriza zizindikiro.

Ngati ndi kotheka, opaleshoni wodwala ayenera nthawi zonse kuchenjeza dzanzi kuti mankhwala.

Pa mankhwala, mankhwala, "metoprolol" M'pofunika kuti azivala zovala zoyenerera. Ichi ndi chifukwa chakuti mankhwala zikhoza thupi lawo siligwirizana ndi khungu chifukwa kukhudzana ndi dzuwa.

Sitingathe kunena kuti mankhwala "Metoprolol" (analogues wa mankhwalawa makamaka) okalamba zingachititse maonekedwe a kuwonjezeka bradycardia, amalembedwa kuchepetsa magazi, atrioventricular chipika. N'chifukwa chake odwala awa amafuna ulamuliro wapadera.

Komanso, pa chithandizo ndi mankhwala sayenera kuyendetsa galimoto ndi kusiya makalasi ntchito woopsawo amene amafuna ndende mkulu ndi zochita psychomotor liwiro. Izo analimbikitsanso kuti chikuonetseratu Mowa.

Alipo analogs mankhwala

Kodi ngati wodwalayo sangathe kugula mankhwala zotchulidwa dokotala, "metoprolol"? analogues ake akupezeka mankhwala aliwonse. Ambiri a iwo ali ndi ofanana mankhwala yogwira, motero ali ndi katundu mofanana anati mankhwala. Mwa awa akhoza kutchulidwa mankhwala zotsatirazi: "Metoprolol ekala", "Metolol", "Metokor Adifarm" ndi ena.

Pambuyo kupeza deta zikutanthauza kuti wodwala analangiza amanena kuti malangizo Ufumuyo, ndi kufunsa dokotala. Ichi ndi chifukwa chakuti kutanthauza kulandira osiyanasiyana kuchokera pamwamba Mlingo njira.

Kodi aliyense mankhwala analogs? Sinthanitsani dokotala kusankhidwa njira kungakhale mankhwala zotsatirazi: "bisoprolol" "Metoprolol-ratiopharm", "Metokard", "Korvitol", "Metozok", "Lidalok", "Serdol", "Egilok", "Emzok" ndi ena.

Kodi kusunga ndi mankhwala zingati?

Tsopano inu mukudziwa tanthauzo, kodi ndi mlingo zimene kumwa mankhwala "Metoprolol". Kusunga pa malo ozizira (mwachitsanzo, mu firiji a) kapena chipinda kutentha si upambana madigiri 25. Pankhaniyi, mankhwala ayenera kutetezedwa dzuwa.

Alumali moyo wa anati mankhwala ambiri a Akhristu ake a zaka zisanu kuchokera tsiku kupanga. Itatha nthawi iyi, mankhwala ntchito mu zolinga achire ndi prophylactic ndikoletsedwa. Izo ziyenera kuchotsedwa.