Mankhwala Kodi odana ndi TB bwino ntchito mankhwala?

Undiagnosed m'mapapo mwanga TB akhoza kuchiritsidwa patatha miyezi 10 kalendala kwa zaka 1.5. Zitenga nthawi yayitali bwanji chithandizo chimadalira pa kuopsa kwa ndondomeko matenda ndi poika abwino kwambiri Zopangidwa mankhwala.

TB mu nthawi yathu - matenda curable

Mu masiku ano TB mankhwala mankhwala ndi mwayi wapadera mankhwala kuphatikiza. Ichi ndi chifukwa pamene munthu nthawi chiphaso cha mankhwala osiyanasiyana zambiri pang'onopang'ono kukula mycobacteria kukana kuti mankhwala. Wodwala amagwira ntchito njira yomweyo Hour 2 kapena 3 mankhwala. Mwamwayi, mwayi wa mankhwala lero zinthu zambiri. Izi zitha kukhala angapo mankhwala 1 TB kapena osakaniza ophatikizana formulations Ine ndi II zino.

Gulu la wothandizira odana ndi TB inamangidwa ndi mlingo wa mogwira awo. Mwa njira, zikomo kwambiri kuti Institute Research athu Kutulukira mankhwala monga "INH". Ichi ndi chimodzi mwa mankhwala akuluakulu a chifuwachi a mitundu, kuti ali ndi mwayi ntchito kwambiri bacteriostatic. Pankhaniyi, makamaka zipatso njira odwala kumene matenda.

Kenako pa mndandanda

The wachiwiri mphamvu ya mankhwala pambuyo "Isoniazid" - ndi "Rifampicin". Kwambiri wokongola komanso zothandiza njira. Yogwira kukonzekera wotsatira akhoza allocated mu ndondomeko izi: "Streptomycin", "Kanamycin" pambuyo "pyrazinamide wokhala" "Ethionamide" ndipo pambuyo pake "Prothionamide" "Ethambutol", ndi 3 kwambiri 'florimitsina "" Pask, "TB "Thioacetazone" mankhwala.

Mankhwala onse vozdeystuyuschie kuti Mycobacterium ndi kuthandiza kuthetsa mavuto matenda a odwala kuti atayikidwa pa gulu la mankhwala odana ndi TB:

1. Antibacterial lalikulu mankhwala odana ndi TB 1 mndandanda
2. mankhwala malo II zino.

Kukonzekera osiyana 1 ndi mizere 2

Mu mzere woyamba ndi mankhwala zazikulu zimene zimati Mwachangu pamwamba pa nthumwi chemotherapeutic ndi ena ofanana awo. Ndi kawopsedwe kochepa.

Antituberculosis mankhwala 2 mizere, kuphatikizapo mankhwala ndi kubwerera, alibe chifukwa abwino kulimbana Koch Wand, ndi ndithu poizoni. Iwo kutumikiridwa kwa odwala ngati thupi Anachita mankhwala nambala 1 kapena tsankho mankhwala zimawonedwa.

ziwerengero Sad limasonyeza kuti mankhwala nthawi iliyonse nzomwerekeretsa m'thupi, i.e. Mwachangu ndi yafupika kwambiri. Komanso chachikulu chotsutsa-TB mankhwala patapita nthawi yina, chifukwa okha kuwasiya chifukwa mycobacteria kukhala chitetezo kwa iwo. Mwachitsanzo, ngati kudzipatula kwa mmodzi yekha makamaka mankhwala, ndiye kukana kuti izo mycobacteria anati m'miyezi 2-4.

mankhwala TB: kugwiritsa ntchito mphamvu mvetsetsa

Zambiri kuukira mankhwala TB bacteriostatic zimakhudzanso mycobacteria, ndiye kumachepetsa virulence awo ndi kupondereza n'zotheka kuchulukana. Mofananamo, "INH" ndi "Rifampicin" pa mlingo kuikapo maganizo ndi mphamvu kuchita bactericidal. Kupeza zotsatira khola zachipatala, komanso kuti awachenjeze ndi kunyalanyaza zisadzachitikenso nkotheka mankhwala odana ndi TB ayenera anapitiriza kwa nthawi yaitali.

Ndi kusankha imeneyi ndi kuika kuphatikiza bwino mankhwala, komanso nthawi ya ntchito yawo ndi mwachindunji amadalira utuluke wodwalayo pa njira nthawi TB, kodi njira zinachitikadi chithandizo yapita (ngati), monga analekerera ndi mtima wa mankhwala ena ku monga Mycobacterium TB tcheru mankhwala osankhidwa.

ngakhale bwino

Kuphatikiza mankhwala odana ndi TB inakonzedwa pa kopanda kuti pulogalamu chithandizo Payenera kukhala mmodzi kapena awiri oyambirira-mzere mankhwala. Kumene, ngati iwo alibe contraindications kapena kusonyeza iwo bata. Pa mlingo uwu kukonzekera zonse ophatikizana zambiri osati zochepa.

Pamene kugawa (memo ftiziologa) ayenera n'komwe kuti zimenezi mankhwala odana ndi TB, monga streptomycin ndi ena ofanana sangathe pamodzi florimitsina, kanamycin ndi mankhwala ena amene ali ndi zotsatira nephrotoxic ndi ototoxic.

Kodi mtundu kukonzekera "Pasi"

"Pasi" - TB mankhwala bacteriostatic zotsatira. Inde kwa masiku asayansi pharmacologists amene anazilenga. wokangalika ndi oyambitsa a TB. Kugwiritsa mankhwalawa zosiyanasiyana ndi localizations zosiyanasiyana TB. Iwo amapereka zotsatira bwino pamene pamodzi ndi kuika zina mankhwala TB kanthu.

Mankhwala ali Latin dzina "PASK-AKRI". Mukhozanso kapena m'matumba 4 ga kapena 100 ga pa gombe mu mankhwala thumba "Pasi" womwe 3.2 aminosalicylate sodium, monga piritsi limodzi - 1 g wa sodium wochuluka Para-aminosalicylate. Miyala yokutidwa ndi likule amateteza m'mimba ndi kugulitsa zimayikidwa kwa zidutswa 50/100/500/1000. mu phukusi.

Kodi bwino kuphatikiza

TB mankhwala "Pasi" mawu a mankhwala ntchito tuberkulostaticheskoy otsika monga isoniazid ndi streptomycin, ndi chifukwa ayenera kugwiritsidwa ntchito molumikizana ndi wothandizila mbali. Kuphatikiza mankhwala kubweza chitukuko cha kukana mankhwala ndi timapitiriza zotsatira za mankhwala concomitant.

Pharmacokinetics "Pasi"

Mankhwala ali mkulu (90%) a mayamwidwe. Iwo zimapukusidwa mu chiwindi. Kuchichita mosabvuta ndi kudutsa zotchinga magazi minofu ndi kugawidwa mu zimakhala ndi. Mlingo wapamwamba ndende mankhwala anati mu mapapo, impso ndi chiwindi. More amtengo "Pasi" (antituberculosis mankhwala) likulowerera mu madzimadzi cerebrospinal. Koma mu nkhani ya kutupa mu cerebrospinal madzimadzi zipolopolo aminosalicylic asidi ndende ndi 10-50% ya ndende mu madzi a m'magazi. Ambiri (80%) za mankhwala excreted makamaka mkodzo.

Kukonzekera II mndandanda

2 mankhwala odana ndi TB angapo a iwo kusankha ndi kuika yake ndi yabwino achire zotsatira mu mawu a detoxification, kuphatikiza komanso mgwirizano kwambiri kusintha yotupa mu minofu m'mapapo, ndipo ngakhale pochiza chifuwa chachikulu cha bronchi ndi.

Malinga ndi akatswiri a zachipatala pa mankhwala a ana ndi akulu ndi njira yovuta, aakulu ndi owononga yatsoka TB ndi ma zosiyanasiyana za mankhwala a angapo II wa, anapatsidwa odwala matenda kukana, ndipo mitundu kugonjetsedwa mabakiteriya mankhwala Ine zino, mu 65 peresenti ya zoterezi chidatengedwa, zimene ziri zokondweretsa kwambiri , zina matenda kwenikweni.

mankhwala TB: mavuto

Ndipo, ndithudi, chidwi amene akutsogolera mankhwala anafotokoza m'nkhani, awo zotheka mavuto. Makamaka chifukwa cha analowa zisakuyenda mu mchitidwe wa mankhwala mankhwala odana ndi TB oyenera mwapadera. Ichi ndi chifukwa chakuti matenda posachedwapa anawoloka mliri pakhomo, ngakhale kwambiri pambuyo pa nkhondo yachiwiri ya padziko lonse kuchepetsa mlingo odwala. Chinanso chofunika n'chakuti kuti chithandizo cha chifuwa chachikulu, ngati tatchulazi, ndondomeko ndi wautali, ndipo kungasokoneze mankhwala monga unaonekera, kapena ambiri osokoneza kapena panthawi yaitali phwando lake.

ena ziwerengero

Pamene TB mankhwala reportable timva ena ndi nthumwi zoweta zotsatira mankhwala mbali ya mankhwala ndi pafupipafupi awo yatsoka kotero zosiyanasiyana monga chikhalidwe cha matenda. Mwachitsanzo, odwala 3148 mu mankhwala nawo wothandizila yogwira ndi mycobacteria, zochita chowawa anali anamuona pa% 12.2 okha a anthu, ndi ambiri a iwo anali chiwonetsero cha chikhalidwe matupi awo sagwirizana ndi kokha odwala 74 panali poizoni poizoni.

Yachokera pa kafukufuku lofalitsidwa, tinganene kuti zotsatira ananena mbali ya odana ndi TB mankhwala mayankho osiyana pafupipafupi. kusinthasintha Large anafotokoza ndi awo mankhwala si yunifolomu ya zinthu zomwe ndi zofunika mankhwala si ntchito kokha, komanso mtundu wa TB, komanso zaka odwala, ngakhale mitundu ya zipatala (chipatala, chipatala chaching'ono, chipatala, bungwe).

Akatswiri

Mankhwala zimawononga Bacillus Koch a, monga nambala ya mankhwala achilengedwe ndi theka-kupanga limene pali chinthu chimodzi chofanana - ndi ntchito yawo ndi mwachitsanzo Mycobacterium TB (M.tuberculosis). TB mankhwala, ndi gulu lomwe, monga tanenera kale m'nkhani ino, ukugawa mankhwala mu 2 mndandanda (pulayimale ndi kubwerera), ndi chidwi chachikulu kwa asayansi.

chidwi ndi chitukuko cha kukana wa oyambitsa TB. zofufuza zonse zasayansi akutsatiridwa, ndi pa nkhaniyi zotsatira anasonyeza kuti ambiri odwala mlingo wa azikana mankhwala pa chithandizo zingasiyane, ndipo m'mwamba ndi kunsi, kufika pa nthawi kubwezeretsa pafupifupi tilinazo.

Kuchepetsa mosiyanasiyana chokhwima

Pamene zochitika chowawa kumachitika nthawi mankhwala, mlingo woyamba wa mankhwala kuchepetsedwa kapena m'malo ena kukonzekera zina. Mu aakulu mlandu mbali anachita antituberculous mankhwala kuti amaletsa yochepa phwando ndi m'malo wotsatira ndi mzake. Pofuna kupewa ndi kuthetsa zizindikiro za inatsekeratu wodwala matenda a mtima akapatsidwa malinga ndi umboni wa aliyense angapo a mankhwala MANKHWALA OLETSA VUTOLI, monga: "Eufillin", "papaverine", "Teofedrin" akutsikira "Zelenin," etc ...

Makhalidwe ndi zovuta zochitika chowawa pa mankhwala TB ndi osiyanasiyana ndithu. Antituberculosis mankhwala, gulu limene maonekedwe enieni a yemweyo mankhwala mbali, m'magulumagulu kuti magawowa kafukufuku.

mankhwala TB

Mankhwalawa matenda tuberculous mu nthawi yathu nawonso ankaona ntchito yofunika kuti kupewa kufalikira kwa matenda. Kuopseza amachokera odwala TB m'mapapo mwanga mu mawonekedwe lotseguka. mankhwala tima ithandiza kuchepetsa chiwerengero cha matenda, komanso kupewa amapezeka za matenda zosasangalatsa.

Popeza mankhwala yaitali, wodwalayo kumafunika kudekha mtima ndi samodistsiplinirovannost. Ndithudi, TB chimawononga osati chidwi ndi thupi, komanso thupi lonse wonse. nthawi zofunika kwambiri kuyamba mankhwala antimicrobial, imene Maphunzirowa ndi zida zankhondo zamphamvu kwambiri, mankhwala estosnovnye TB. Chifukwa cha iwo, koma n'zotheka kuchotsa oyambitsa mu magawo oyambirira, omwe amathandiza kuti kubwezeretsa kwa chiwalo akhudzidwa ndi kuwonongeka kwenikweni lake lonse.

chithandizo Mabuku zimene tikubweretsazi kutenga nkhani msinkhu ndi mitundu amadziŵika ndi nthendayi, zikuphatikizapo zotsatira pa njira pathological wa limba matenda, kuchepetsa zizindikiro concomitant (ululu, chifuwa) ndi inhalations osiyana ndi luso thupi mankhwala.

Chikuonetseratu anasankha gulu la mankhwala ayenera kukhala wokhazikika ngati mfuti njira angachititse chitukuko cha kukana kwa iwo. Chithandizo ayenera kuchitika kuchipatala kuyang'aniridwa ndi dokotala. Pambuyo kumaliseche phthisiatrician kuyang'aniridwa.

Akuluakulu njira ndi kukhazikitsa mankhwala mankhwala ndi zolinga ndi chinsinsi kumaliza kuchira. Masiku ano TB si chiweruzo.