Kukonzekera ketotifen: ndemanga ndi malangizo ogwiritsidwa ntchito

Mankhwalawa "Ketotifen" ndi gulu la antchito a cycloheptathiophenone, omwe amatchulidwa kuti antihistamine.

Njira yothandizira mankhwala "Ketotifen"

Malingaliro a madokotala akusonyeza kuti mankhwalawa amaletsa kumasulidwa kwa maselo a mbiri yakale a histamine, otseka histamine receptors, amaletsa michere ya phosphodiesterase. Pogwiritsira ntchito mankhwalawa, mlingo wa cyclic adenosine monophosphate mu maselo akuluakulu amakula. Mankhwalawa akuphatikizapo kuthetsa zotsatira za zinthu zowonongeka. Mankhwala samapereka mpumulo wa masewera a asthmatic, koma amalepheretsa kuchitika kwawo, amachepetsa mphamvu ndi nthawi, nthawi zina, zimawonongeka. Mankhwalawa ali ndi zotsatira zabwino pa sputum.

Kupanga ndi pharmacokinetics pakukonzekera "Ketotifen"

Maphunziro a asayansi ndi malangizo ogwiritsiridwa ntchito amasonyeza kukhalapo kwa mankhwala opangidwa ndi mankhwalawa - ketotifen fumarate.

Mankhwalawa amapezeka kwambiri ndi thupi. Kupezeka kwa mankhwalawa ndi 50 peresenti, mankhwalawa amalephera kuthetsa vuto la magazi. Metabolism amapezeka m'chiwindi, mankhwalawa amatulutsidwa ngati metabolites ndi impso. Kuchuluka kwa mankhwala kumatulutsidwa kudzera impso kwa masiku awiri.

Zisonyezo za kutenga Ketotifen

Maphunziro ndi mayankho a madokotala amati mankhwalawa ndi chida chothandizira kuchipatala cha atopic bronchial asthma ndi dermatitis, hay fever, allergen rhinitis ndi conjunctivitis, ndi ming'oma.

Mankhwalawa amawoneka ngati mapiritsi a 1 mg ndi manyuchi "Ketotifen".

Ana osapitirira zaka zitatu amalembedwa 1 mg wa mankhwala mumtundu uliwonse kawiri pa tsiku. Akulu ayenera kumwa mankhwala omwewo m'mawa ndi madzulo. Ngati ndi kotheka, mlingowo umapitsidwanso kawiri. Mankhwalawa amadya ndi chakudya mkati. Kutalika kwa mankhwala ndi miyezi itatu. Kuchetsedwa kwa mankhwala kumapangidwa mkati mwa masabata awiri.

Kusamvana ndi zotsatirapo za kutenga Ketotifen

Umboni wa odwalawo umatsimikizira kuti zochitika zoterezi ndizozungulira, kugona, kuchepetseratu kuthamanga, kumva kutopa. Pogwiritsira ntchito mankhwalawa, pamakhala kugwedezeka, kugona kumatha kusokonezeka, nkhawa, mantha pakati pa ana. Kuonjezera apo, odwala amamva mkamwa wouma, amakhala ndi chilakolako chowonjezeka, akhoza kuyamba kusanza kapena kunyoza, kudzimbidwa. Kusokoneza maganizo ndikuphatikizapo thrombocytopenia, chifuwa, kupweteka.

Mankhwalawa "Ketotifen", madzi ndi mapiritsi, sakuvomerezeka kuti agwiritsidwe ntchito panthawi yomwe ali ndi pakati komanso nthawi ya lactation. Ndiletsedwa kumwa mankhwala osapitirira ana atatu, komanso hypersensitivity kuti zigawo zikuluzikulu.

Ketotifen: malangizo apadera

N'zosayenera kuwononga zakuthwa za mankhwala kwa odwala matenda a bronchospastic ndi bronchial mphumu. Chithandizo chaima bwino, kuchepetsa mlingo mkati masabata awiri kapena anayi.

Odwala omwe ali ndi chidwi ndi sedation, mankhwalawa amalembedwa ndi mankhwala ochepa. Mankhwalawa sali othandizira kuchiza matenda a mphumu. Pogwiritsidwa ntchito pamagulu a hypoglycemic agwiritsidwe ntchito ayenera kufufuza kuchuluka kwa mapiritsi m'magazi amagazi.

Mankhwalawa amakhudza kuthekera kwa magalimoto ndi njira, kotero muyenera kupewa ntchito izi panthawi ya chithandizo.

Mankhwalawa amachititsa kuti mapiritsi asagone, ethanol ndi antihistamines, komanso kuphatikizapo mankhwala a hypoglycemic, amachititsa kuti pakhale vuto loti likhale ndi thrombocytopenia.

Mankhwala ofanana amaperekedwa ndi kukonzekera Zaditen, Ketof, Stafen, Positan.