Kodi inu mumawatcha mankhwala okwera mtengo kwambiri mu dziko?

Ndalama za makampani ena mankhwala adagulung'undisa pa biliyoni. Ichi ndi chifukwa chakuti iwo kupulumutsa mankhwala okwera mtengo, opangidwa ku magulu ang'onoang'ono. Kawirikawiri mankhwala, kupewa pathologies osowa. Akatswiri ena amakhulupirira kuti ndalama zina mankhwala ndi wapamwamba kwambiri chifukwa chakuti palibe mpikisano. A mndandanda wa mankhwala amenewa ndi yaikulu kwambiri pakati pawo mtengo kwambiri mu dziko la mankhwala ndalama zoposa wani miliyoni mumauro.

Mankhwala Aldurazyme

mankhwala lakonzedwa kuchitira Hurler syndrome, amene kumaonekera mwana. Iye akudwalanso anthu pang'ono kuposa mazana asanu lonse. Matenda kumabwezera mmbuyo thupi ndi makhalidwe chitukuko cha ana aang'ono monga zinayi.

Mtengo a malo pafupifupi madola thuu handiredi sauzande.

Mankhwala "Cerezyme"

Pa mtengo wa mankhwala ndalama za yofanana monga Aldurazyme. "Cerezyme" - n'chimodzimodzi ndi mankhwala okwera mtengo kwambiri mu dziko. Izo analamula kuti matenda Gaucher. Matendawa yodziwika ndi kudzikundikira madipoziti mafuta mu mapapo, chiwindi, ubongo ndi mafupa. mtundu uwu anayamba kuchepa kunenepa zovuta ntchito ya m'mapapo ndi impso. Mankhwala m'malo mwa enzyme ndi matenda Gaucher palibe kwathunthu.

Padziko lonse, anthu ali ndi matenda ili pafupi zikwi zisanu ndi anthu.

The Myozyme mankhwala

Pali mazana a mankhwala osokoneza bongo ndipo ndalama zokwana mayuro zoposa zikwi pa vial. mankhwala onsewa a gulu la "mankhwala okwera mtengo kwambiri mu dziko." dzina la mankhwala wina mu gulu limeneli ndi liti? Izi mankhwala Myozyme, zochizira matenda Pompe. A kudwala yodziwika ndi akusowa wa alpha-glucosidase. Zimenezi zimabweretsa kuwonongedwa kwa minofu ndi kuwonjezeka lakuthwa mu buku la mtima, kukhala kudwala kupuma. Nthawi zambiri, matenda ndi wapezeka ana.

Kugwiritsa ntchito mankhwala akhoza kusiya njira ndipo amathandiza ana amayamba kupuma paokha. Mtengo wa wothandizila chithandizo ndalama zikwi zana mayuro mwana. Ngati nthendayo anapezeka mu akula, ndiye mankhwala kutenga oposa mazana atatu ndi zikwi.

zikutanthauza Fabrazyme

Wina mankhwala okwera mtengo kwambiri dziko - ndi njira Fabrazyme. Mtengo wa mankhwala ndalama pafupifupi madola zikwi.

Mankhwala anayamba zochizira matenda Fabry. Izo zimayambitsa kutengeka moto, ndi anawonjezera mtima, vuto la impso. Padziko lonse lapansi, anthu akuvutika ndi matenda, palibe kuposa anthu zikwi zitatu.

The Arcalyst mankhwala

Ena amakhulupirira kuti mtengo kwambiri mu dziko la mankhwala - ndi sewerolo mankhwala Regeneron otchedwa Arcalyst, zochizira Syndrome Muckle-Wales. Kudwala ndi kumatchula likukulira malungo, molumikizana mafupa, impso. Disease kumakhudza pafupifupi miliyoni padziko lonse.

Mtengo wa mankhwala ndi mazana awiri ndi asilikari zikwi makumi awiri dollars.

The Soliris mankhwala

M'mbuyomu, mankhwala okwera mtengo kwambiri dziko - Soliris. Mtengo wa mankhwala pafupifupi hafu miliyoni madola. Zikutanthauza pochiza matenda amene chitetezo cha m'thupi umawononga maselo ofiira a magazi. mankhwala Izi anatenga amuna zikwi zisanu.

Mankhwala ndi Elaprase Naglazyme

mankhwala wina ku gulu la mankhwala okwera mtengo kwambiri dziko - ndi mankhwala Elaprase. mtengo wake ndi madola zikwi mazana anai. Njira anasonyeza kuti syndrome Hunter. Pakuti pathologies yodziwika ndi ponso chinenero, kuwonongeka kwa bongo ndipo ankawachotsera mphuno. Padziko lonse, mankhwala amatenga pafupi anthu zikwi ziwiri.

Pafupifupi mtengo womwewo Naglazyme. Iwo Kwalamulidwa kuchitira Maroto-Lamy. Syndrome amakhudza anthu oposa zikwi kuzungulira dziko. Matendawa yodziwika ndi milomo wandiweyani, aafupi ndi mutu waukulu. Kale kwa m'badwo odwala khumi njinga ya olumala.

Cinryze

Izi mankhwala - mankhwala okwera mtengo kwambiri mu dziko ndipo yankhoyi ifunika ndalama zoposa zikwi mazana atatu. mankhwala lakonzedwa kuchitira cholowa angioedema mtundu. Mu matenda ichi chinawonetseredwa chitetezo mkhutu, amachititsa kutupa choopsa cha milomo, zonse m'mimba.

The mankhwala okwera mtengo kwambiri

Kotero mankhwala okwera mtengo kwambiri mu dziko? Kodi ndindalama zingati? makampani awiri zakunja apanga mankhwala okwera mtengo kwambiri mu dziko. Glybera umatchedwa. Mtengo wa chithandizo malo uyu adzakhala oposa miliyoni mumauro.

mankhwala jini latsopano cholinga zinthu ndi osowa majini matenda - lipoprotein lipase akusowa. The puloteni nthawi mlingo wa lipids mu thupi. Chifukwa jini kusintha enzyme si opangidwa ndi thupi, chifukwa ali mkulu chiopsezo mtima occlusion.

botolo limodzi mankhwala ndalama yuro zoposa zikwi makumi asanu, ndipo kwathunthu ya chithandizo cha matenda adzakhala oposa. odwala oyembekezera ndi matenda ichi, pali mazana awiri anthu ku Ulaya, kotero chida n'zokayikitsa kukhudza aliyense pa bajeti ya mabungwe a zaumoyo.

Ngakhale mtengo, chida amatha kuchiza kwathunthu kudwala. Malinga ndi kutukula, ndi njira ya mankhwala ndi mtengo angapo enzyme m'malo mankhwala.

Mankhwala Glybera jini malo chachinayi mu dziko. Woyamba awiri anayamba asayansi American ndi opangidwa ku China. Zida onse tinapangidwa zochizira khansa, ndicho khansa khomo lachiberekero ndi zotupa pa mutu. njira yachitatu mu Russia. chida ichi amatchedwa "Neovaskulgen", anafuna kuti mankhwala a m'munsi nthambi ischemia. The njira ya mankhwala ndi mankhwala ndalama pafupifupi zikwi rubles.

mabungwe Biotechnological amakhulupirira kuti mankhwala okwera mtengo kwambiri mu dziko, zithunzi za amene angapezeke mu nkhani cholakwika yokha. Ndipotu, kufikira Kubwera kwa mankhwala, anthu ambiri akuvutika pathologies kwambiri, sanathe kuchotsa matenda awo. makampani opanga mankhwala ndi kopindulitsa kugulitsa mankhwala, kuyambira malonda awo safuna ndalama. Komanso mankhwala awa ndi pafupifupi munthu mpikisano, chomwe chimathandiza opanga okha kudziwa mtengo wa mankhwala ndipo limapezeka.

Mu inshuwalansi United States makampani reimburse mtengo wa mankhwala okwera mtengo kwa odwala, ndipo ena opanga kupereka ufulu mankhwala osowa.

Akatswiri padziko lonse kulungamitsa kukwera mtengo kwa mankhwala atsopano. Malinga ndi iwo, kugwiritsa ntchito mankhwala amenewa amalola ambiri odwala pang'ono, ndi zina Yamba kwathunthu ndiyotani pakuchotsa syndromes osachiritsika. Akatswiri amakhulupirira kuti mtengo wa mankhwala awa kuchepa mpikisano chofunika. Ndi anthu pang'ono basi ndikuganiza kuti anthu amene apeza matenda, ndipo ngakhale ali aang'ono, ndi chodziwikiratu kuti athe kugula mankhwala, kugulitsidwa zikwi. Nthawi zambiri, anthu alibe mwayi kugula mankhwala amenewa mtengo.