"Excedrin": Anzawo. The mankhwala migraine "Excedrin": ndemanga, mitengo, analogs

Migraine - ichi ndi matenda, amene sakhoza anasamutsa popanda analgesics. kuukira amatha kwa masiku 4. Munthu mu nthawi ino wotaya mphamvu yake ntchito. Pa nthawi yomweyo amagwiritsa ntchito mankhwala amphamvu kuchotsa ululu womwe throbbing. Koma, mwatsoka, ambiri a zipangizo zimene angathe kuchotsa kusamva amenewa, osokoneza ndi kutsogolera chakuti matendawa amakhala aakulu. Modern mankhwala zachitika waukulu mankhwala atsopano. Njira bwino kuchotsa migraine, kuchepetsa luso ntchito, koma si kuwasiya, mankhwala ndi "Excedrin". Analogs mankhwala si sakhala ogwira.

Kufotokoza mwa chidule za

The mankhwala migraine "Excedrin" ndi kukonzekera ophatikizana cha gulu la analgesics-antipyretics. Izo ntchito mutu kwambiri. Mogwira amatanthauza "Excedrin" ku mutu waching'alang'ala. Mu nkhani iyi, ngakhale kupewa nkhondo.

The zikuchokera mankhwala

mogwira mankhwala a lagona kaphikidwe kake. mankhwala lili:

• asidi acetylsalicylic;
• Kafeini;
• paracetamol.

Ndi kuyamika zinthu izi mavuto osiyanasiyana m'thupi. Chifukwa, kungakupatseni Zotsatira zake atangochimwa, kwathunthu atazikocheza ululu.

Paracetamol mu kuchuluka kwa 250 mg, Acetylsalicylic asidi - 250 mg, ndi tiyi kapena khofi - 65 mg wa piritsi limodzi lili mankhwala "Excedrin". The zikuchokera Choncho m'bukuli zikutanthauza yogwira zosakaniza ndi yofunika kwambiri. Choncho tikulimbikitsidwa kugwiritsa ntchito mankhwala mosamala kwambiri. Odwala ayenera kuganizira mlingo ndipo musapyole izo.

Komanso, mankhwala monga zosakaniza wothandiza:

• giproloza;
• microcrystalline mapadi;
• asidi stearic.

Mmene thupi

Mapiritsi migraine "Excedrin" yopangidwa ndi zisulo zitatu zosiyana zomwe ndi katundu osiyana. kuphatikiza awo zimathandiza kuchotsa ululu wa chikhalidwe chilichonse. Popeza kuukira migraine limodzi ndi mokwanira yaitali ndi aakulu kusapeza, kuti amuchotsepo Iye ayenera kukhala mankhwala amphamvu kwambiri. Kuti ndi mankhwala "Excedrin".

Kodi chida ichi nayenso anafotokoza mmene iye ndi zimenezo? Yankho la funso lili tingati pa thupi lililonse chigawo ali mankhwala:

1. Paracetamol. thunthu ali apamwamba odana ndi yotupa ndi antipyretic katundu. Iwo akhoza bwanji pakati ubongo udindo kulamulira kutentha ubongo imene imalamulira kutentha kwa. Yofunika kwambiri pothetsa migraine iwo ali wotsutsa-yotupa quality, chifukwa malungo sikuli kwa zizindikiro za matenda.
2. asidi Acetylsalicylic. Chigawo losiyana kutchulidwa antipyretic katundu. Iye amatha kuchedwetsa ndi kuthetsa kutupa. Mu ichi amachepetsa ululu. asidi Acetylsalicylic chingalepheretse zosayembekezereka wa magazi kuundana. Ndi kugwira ndondomeko mapangidwe awo pa mlingo ma, mwangwiro timapitiriza magazi m'madera chofuna.
3. Tiyi kapena khofi. Udindo wa mankhwala kuti kuchepetsa ululu kwambiri. Aspirin ndi paracetamol angathe kuchotsa mongoyembekezera ndi nkhawa. Kafeini kuli ndi ubwino pa magazi mu ubongo ndipo amathandiza tichotse zimayambitsa matenda. Komanso kumapangitsa kupuma ndi vasomotor malo, amalimbikitsa kukula kwa mitsempha mwapang'ono, kumathandiza kupatsidwa zinthu za m'mwazi kumanga. Tiyi kapena khofi ndi relieves kwambiri kutopa ndi tulo. Izo kwambiri kumawonjezera dzuwa la lake ndi kamvekedwe ake, potero chikusintha wodwala matenda wonse. Kuphatikiza a aspirin ndi thunthu angathe utithandize magazi ndi zabwino bwanji ziwiya ubongo.

Pathologies imene lokonzekera umagwiritsidwa

Iwo m'pofunika kugwiritsa ntchito "Excedrin" mankhwala kuti ululu syndromes wa wofatsa ndi zolimbitsa mphamvu ya chiyambi osiyana:

• migraine;
• mutu;
• neuralgia;
• kwa dzino;
• myalgia, arthralgia (kusapeza mu mafupa ndi minofu);
• algomenorrhea (ululu kusamba);
• thupi syndrome.

Pharmacokinetics

Nthawi zambiri, thupi mankhwala "Excedrin" ndithu kupirira. Ogula ndemanga kwathunthu akutitsimikizira izi. Chotero zotsatira za mankhwala chofunika zigawo zake:

1. Paracetamol mwangwiro odzipereka kapepala kakuti m'mimba. Iwo zimapukusidwa mu chiwindi, impso ndi excreted monga glucuronide ndi sulphate conjugates. Pasanathe 5% ya lotulukira zinthu mu mawonekedwe unmodified. Popeza plasma mapuloteni ubale ndi kanthu ntchito ochiritsira achire mlingo. Koma ndi kuwonjezeka mu inawo - zikuchulukirachulukira. Hydroxylated metabolite anapanga zochepa mu chiwindi mchikakamizo cha oxidases wosanganiza ndi zambiri ndi zopanda ndi kumanga kwa glutathione, akhoza kudziunjikira ndi ambiri osokoneza wa paracetamol ndi kuwononga chiwindi.
2. asidi Acetylsalicylic kwathunthu ndipo mofulumira odzipereka. Iwo hydrolyzed mu m'mimba thirakiti, magazi ndi chiwindi. Mu mawonekedwe salicylates. Komanso zimapukusidwa mu chiwindi.
3. Kafeini amadziwikanso mofulumira odzipereka kwathunthu. Ndende pazipita mu thupi anati kwa mphindi 5-90 pambuyo ntchito ndalama pa chopanda kanthu m'mimba. Excretion kumachitika chifukwa cha kagayidwe kwa chiwindi. thunthu ndi anagawira pa madzi onse thupi. Kulankhulana ndi mapuloteni plasma 35%. Chigawo kwathunthu zimapukusidwa ndi excreted ndi impsozo.

dosing kamwedwe

Oyenera makonzedwe m'kamwa amatanthauza "Excedrin". Mankhwalawa amagwiritsidwa ntchito pa kapena pambuyo chakudya. Ndi bwino kumwa madzi lalikulu zedi.

Single mlingo akuluakulu ndi achinyamata (kwa zaka 15) - ndi piritsi 1 lililonse 4-6 maola. Ngati munthu akuona Zizindikiro za migraine zam'tsogolo, Ndi bwino kugwiritsa ntchito nthawi yomweyo 2 mankhwala. Izi kuteteza kuukira kwa matenda. Komabe, munthu ayenera kukumbukira kuti zimawononga mayunitsi oposa 6 pa tsiku koletsedwa.

chenjezo zofunika

mankhwala ogwira analola kuti ndilembe kusapeza chopweteka masiku 3. Panthawi imeneyi, wodwala ayenera kuonana ndi dokotala, amene adzakhala kusankha wangwiro kudzera njira imene kulimbana ndi matendawa.

Nthawi zina, mtima ndi bwino kuwonjezera ntchito mankhwala. Koma kusankha wotero kukhala pa maziko a zizindikiro zoyenera yekha katswiri. Kudya mankhwala migraine "Excedrin" masiku oposa 3 ali osavomerezeka. Kuwonjezeka mlingo angathe kuchititsa mavuto aakulu. Monga kuwonongeka chiwindi chifukwa kudzikundikira metabolites mu thupi.

zotsatira zoyipazi

Kugwiritsa ntchito mankhwala sikungathandize kwenikweni ndi zotsatira zabwino pa thupi. Popeza angapo mavuto amatanthauza "Excedrin". Mankhwala analogues angakulangizeni kuchitira dokotala, ngati tatchulawa mankhwala ndi yosayenera la wodwalayo.

Choncho, zotsatira zotsatirazi mbali:

• nseru, kusanza;
• gastralgia;
• hepatotoxicity;
• erosive ndipo anam'peza m'mimba zotupa;
• nephrotoxicity;
• thupi lawo siligwirizana;
• amayamba kuthamanga;
• tachycardia;
• chizungulire;
• bronchospasm;
• mutu;
• amaona masomphenya;
• ndichepe mu kupatsidwa zinthu za m'mwazi loitanirana ;
• tinnitus;
• hemorrhagic matenda (magazi m'kamwa, epistaxis, purpura);
• zilonda exudative erythema (kapena matenda Stevens-Johnson);
• ugonthi;
• poizoni epidermal necrolysis (kapena matenda Lyell a);
• matenda a impso (Chance papillary necrosis);
• chitukuko ana syndrome Raynaud a (hyperpyrexia, kagayidwe kachakudya acidosis, matenda ya ubongo ndi psyche, kusanza, nthenda chiwindi ntchito).

Contraindications kulandira

Mwatsoka, mankhwala sadzagwira ntchito kwa anthu onse. Pambuyo njira angapo a contraindications. Iwo ndi otsimikiza kuti n'komwe patsogolo ntchito. Koma kufooka ngati mankhwala samabwera popanda ndalama. Dokotala kupezeka zosavuta m'malo chida "Excedrin". Analogs kulola kuti tikwaniritse ndi chifukwa zovomerezeka.

Mankhwala contraindicated mu pathologies izi ndi zinthu:

• Hypersensitivity kuti zosakaniza;
• zilonda m'mimba mu gawo pachimake;
• bronchial mphumu,
• magazi m'mimba;
• kobwereza m'mphuno polyposis (paranasal sinuses);
• tsankho kwa NSAIDs;
• popanga munthu opaleshoni kuti ayende magazi;
• hemorrhagic diathesis;
• oopsa;
• amapatsira mwana wake;
• gipoprotrombinemii;
• oopsa zipata;
• khungu;
• aakulu ischemia za mtima;
• beriberi K;
• kusowa kwa shuga-6-mankwala dehydrogenase;
• aimpso kulephera;
• mimba;
• mkaka wa m'mawere;
• matenda tulo;
• irritability;
• zaka ana (a mankhwala siligwira ntchito kwa zaka 15).

ambiri osokoneza wa mankhwala

Medicine "Excedrin" migraine okha ndiwo ayenera amwedwa tanena. Popeza nkhanza wothandizila kungachititse kuti khamu zizindikiro zosasangalatsa.

About ambiri osokoneza wa paracetamol akusonyeza mbali zotsatirazi:

1. Pa tsiku loyamba wotumbululuka khungu, kusanza, kupweteka m'mimba, mkhutu shuga kagayidwe, anorexia, kagayidwe kachakudya acidosis.
2. Patapita maola 12-48 ntchito zizindikiro zotheka kulephera chiwindi anasonyeza kupitirira wa encephalopathy. Pakuti kwambiri ambiri osokoneza zotheka - chikomokere ndi imfa. Pangakhale aimpso kulephera pamodzi ndi necrosis tubular, kapamba, arrhythmia.

Ambiri osokoneza chikwiyire ndi asidi acetylsalicylic, ali ndi zizindikiro zotsatirazi:

1. Wofatsa - kusanza, chizungulire, kusawona bwino, tinnitus, mutu.
2. Mu poyizoni aakulu - kufupika kwa mpweya, cyanosis, dyspnea, yomata ozizira thukuta, kupuma acidosis, kupuma ziwalo.

Nkhanza chifukwa cha Kafeini chimaoneka ndi zizindikiro zotsatirazi:

• gastralgia;
• mukubwadamuka, nkhawa;
• chisokonezo;
• m'chikaiko chowakaikitsa;
• madzi m'thupi;
• arrhythmia;
• pafupipafupi pokodza;
• tachycardia;
• hyperthermia;
• padzakhala ululu ndi tcheru;
• kugwedeza;
• akamaganizira ya;
• nseru, kusanza (zina ndi kukhalapo kwa magazi);
• khunyu khunyu.

Ngati ambiri osokoneza afunefune thandizo pangozi. Pa tsiku loyamba maola 4 Ndi bwino kuti asambe m'mimba, kupangira kusanza. Mankhwalawa ayenera kudyedwa ndipo limatanthauza 'adamulowetsa mpweya ".

analogues mankhwala

Kumbukirani kuti mankhwala aliyense ayenera zotchulidwa dokotala, pakuti uliwonse wothandizila ali zizindikiro zake ndi contraindications.

Ndipo yekha dokotala angathe mmalo mankhwala ena mankhwala "Excedrin". Analogs wa chigawo panopa motere:

• "Akvatsitramon".
• "Atsifein".
• "Askofen".
• "Kofitsil kuphatikiza."
• "Tsitramarin".
• "Migrenol zopezeka."
• "Tsitramon".
• "Tsitrapar".

Mtengo wa mankhwala

Pakuti dzuwa ake onse, yotchipa ndalama mankhwala ogula "Excedrin" ku mutu waching'alang'ala. Mtengo wa phukusi (mapiritsi 10) zimasiyanasiyana mu osiyanasiyana 120-150 rubles. Mtengo wa lokonzekera mapiritsi 20 210-250 rubles.

Mwanjira ndi mankhwala ena

Odwala amene mankhwala "Excedrin" Tiyenera timvetsetse kuti umathandiza bwanji thupi njira zina monga:

• "Heparin";
• mosadziwika anticoagulants;
• "Reserpine";
• mankhwala hypoglycemic;
• steroid mahomoni.

Onani kuti ntchito munthawi yomweyo ndalama "Excedrin" ndi NSAIDs ena kuyambitsa zotsatira zoyipa. Mwachitsanzo, mogwirizana ndi mankhwala protivopodagricakih, mankhwala antihypertensive, amatanthauza "Furosemide" kumayambitsa Mwachangu otsika a magulu awa mankhwala.

ogula maganizo

mankhwala aliwonse ali (nazonso ndi mankhwala "Excedrin") mayankho, zabwino ndi zoipa.

Ena ogula ndikuuzeni moona mtima kuti, popeza anayesa mankhwala kamodzi, sadzatero gawo ndi iwo. Akazi ambiri ali chida champhamvu mu chikwama chake. Inu konse pamene ululu kuukira adzakhala kukupezani. odwala amenewa zindikirani kuti munthu piritsi angathe ola kuthetsa zizindikiro zosasangalatsa. Ndipo pa nkhani ya mutu waching'alang'ala aakulu kumatha ululu mankhwala mankhwala 2 "Excedrin". Mayankho akusonyeza kuti dzuwa kwambiri cha chida.

ogula ena kusungira munjira ina, kulengeza kupanda pake kwa mankhwala. Iwo amanena kuti yogwira mankhwala zikhoza kugulidwa payekha ndi mtengo kwambiri kuposa mankhwala a. Komabe, makasitomala izi kuiwala kuti ukhale wogwira mtima mankhwala zinali za mitundu lamanja la zigawo zikuluzikulu zonse azigwirizana mwangwiro.