"Dekapeptil": malangizo ntchito, zikuchokera, zizindikiro ndi contraindications

Kodi ntchito mankhwala "Dekapeptil"? Malangizo ntchito mankhwala Adzaperekedwa pansipa. Mudzaphunziranso za zikuonetsa ntchito mankhwala, analogs ake ndiponso zinthu zina chokhwima.

"Dekapeptil": ikulongosola za mankhwala, kapangidwe kake ndi mtundu

Ankaona medicament chogulitsidwa monga jekeseni bwino ndi colorless popanda palibe fungo ndi zosafunika.

The chigawo chachikulu cha mankhwala ndi triptorelin nthochi. Komanso zikuphatikizapo zosakaniza monga asidi glacial acetic, sodium kolorayidi ndi madzi a jekeseni.

Kugula njira "Dekapeptil" chithunzi chimene m'nkhani ino akhoza kukhala syringes, mbale, wangwiro ndi singano, amene mmatumba maselo mizere ndi makatoni, motero.

Zochita za mankhwala (pharmacological)

ndi yankho "Dekapeptil" n'chiyani? Malangizo ntchito ikusimba kuti analogue kupanga a GnRH, kapena otchedwa gonadotropin-kumasuka timadzi.

Pambuyo utsogoleli wa mankhwala yogwira chinthu izo zimayambitsa kuwonjezeka mlingo wa LH ndi FSH mu mwazi kumene n'kukumana kuwonjezeka chosakhalitsa mu ndende mahomoni kugonana. Wopitiriza kukondoweza kwa pituitary (mwachitsanzo, pa ntchito zonse za mankhwala) kumathandiza anatseka misewu gonadotropic ntchito. The chifukwa cha zotsatira amenewa ndi kuchepa kwa chiwerengero mahomoni (kugonana) kuti azimayi amsinkhu umenewu amakumana kapena postcastration. Zimenezi kusintha.

Studies pa nyama zasayansi analibe mutagenic kapena teratogenic zotsatira ankaona mankhwala.

The pharmacokinetics a jekeseni mankhwala

katundu Kodi pharmacokinetic khalidwe la "Dekapeptil" njira? Malangizo Ntchito limati mu mphindi 50-90 choyamba pambuyo akuluakulu a mankhwala magazi ukufika pachimake triptorelin. ndende Komanso zinthu izi ndinasintha yafupika (masana).

Hafu ya moyo nthawi ya chigawo chachikulu ndi mphindi 18,7. About 4% ya triptorelin amapezeka mu mkodzo mu mawonekedwe sichinasinthe.

Tikumbukenso kuti pharmacokinetics mayesero mankhwala ankachiritsa anthu ndi matenda anatsimikizira a fibroids uterine kapena endometriosis, komanso odzipereka wathanzi mwamuna ndi odwala carcinoma a prostate.

Zikuonetsa kuti ka njira injectable

Kodi cholinga prescribers "Dekapeptil"? Zikuonetsa ntchito njira yothetsera akazi:

• fibroids uterine;
• osabereka mankhwala pogwiritsa ntchito njira zamakono ubereki (mwachitsanzo, mwana wosabadwayo kutengerapo, lidzawagwiritsenso);
• endometriosis.

Amuna, ndi chida analimbikitsa zochizira symptomatic wa timadzi amadalira patsogolo carcinoma a prostate.

Ziletso kumayambiriro mankhwala kwa amuna ndi akazi

Nthawi zina, simungathe kulowa mu njira "Dekapeptil"? Malangizo ntchito akusonyeza kuti mankhwala ali contraindicated kwa akazi:

• pamene kuyamwitsa;
• mimba;
• mawonetseredwe matenda ndi chiopsezo cha kufooka kwa mafupa.

Iwo ayenera kukumbukira kuti mosamala mankhwala ntchito kuphedwa kwa pulogalamu odwala lidzawagwiritsenso ndi mazira polycystic (i.e., ngati chiwerengero cha follicles, amene anatsimikiza ndi ultrasound, ndi oposa 10).

Kwa kugonana mphamvu ankaona mankhwala ali contraindicated mu:

• ndi castration opaleshoni (isanafike);
• Prostate carcinoma (timadzi palokha).

General kuletsa kuti kopita kwa chida ndi hypersensitivity kuti triptorelin mtima kapena zigawo zina za mankhwala.

The njira "Dekapeptil": malangizo ntchito

mankhwala cholinga cha utsogoleli subcutaneous. Mu endometriosis, khansa ndi khansa uterine mankhwala ndi kutumikiridwa mu kuchuluka kwa 0.5 mg / ml kamodzi pa tsiku kwa sabata. Pa tsiku la 8 pochitika ndi kukonza mlingo wa 0.1 mg / ml kamodzi pa tsiku.

Mankhwalawa wothandizila izi chofunika kuchita ultrasound ndi polojekiti zamitundu fibroids ndi endometriosis foci.

Pamene lidzawagwiritsenso pulogalamu medicament chikuyendetsedwera malinga ndi ndondomeko (akhoza kukhala lalifupi kapena ultrashort). Pofuna kupewa jekeseni malo zochita pambuyo jekeseni aliyense kusintha nthawi.

Pamene ntchito njira "Dekapeptil Depot"? Malangizo Ntchito limanena kuti chida ichi akuonetsedwa pa nthawi yaitali mankhwala. Amagwiritsidwanso kutumikiridwa subcutaneously m'dera m'mimba, kapena intramuscularly 1 nthawi mu masiku 30.

Yankho okonzeka ankagwiritsa ntchito yomweyo. Endometriosis ndi uterine myoma mankhwala kumayambira masiku oyamba a kuzungulira. Mankhwalawa ayenera lolimba za 3-6 miyezi. Pamene mankhwala khansa ndi anagwiritsanso kwa nthawi yaitali.

Pamene lidzawagwiritsenso mankhwala "Dekapeptil Depot" kutumikiridwa kamodzi pa masiku ena a kuzungulira.

Zochitika mwa khalidwe

Kamene kamayambitsa zosiyanasiyana chokhwima "Dekapeptil" njira? Malangizo, ndemanga mwasonyeza kuti mavuto, amene anaonekera pa maziko a ntchito mankhwala chifukwa kuchepa kwa chiwerengero cha mahomoni kugonana magazi, zimene mapeto ake chitukuko cha zizindikiro monga matenda, maganizo lability, pafupipafupi mutu, kufooka kwa libido, kugona chisokonezo , kutentha cheza, kunenepa kwambiri, ndi kuchuluka thukuta. Komanso, kusintha awa akhala anati odwala ena:

• kutsekeka kwa thirakiti mkodzo, paresthesia, ululu panthawi yogonana;
• amaona masomphenya, kupweteka kwa nsana, kufooka minofu;
• akazi - magazi uterine ndi dryness ukazi;
• amuna - gynecomastia, yafupika potency ndi kuchepetsa kukula kwa machende ndi;
• nseru, ankatenthetsa, kusowa chilakolako oyabwa;
• malungo, hypercholesterolemia, ululu fupa chifukwa cha metastases;
• myalgia, msana psinjika, anaphylaxis;
• arthralgia, ululu pa jekeseni malo mankhwala, fupa demineralization (ndi ntchito yaitali);
• lymph kukulitsa mfundo, thrombophlebitis, mapazi atupa;
• imfa ya tsitsi pa miyendo, chifuwa ndi manja, kuchepetsa kukula ndevu.

Tikumbukenso kuti onse zotsatirapo zimenezi nthaŵi yomweyo pambuyo pa mapeto a mankhwala.

Mwanjira mankhwala, overdoses

Overdoses ankaona mankhwala unkachitika. Ndi chitukuko cha zizindikiro zoipa pa maziko a Mlingo owonjezera mankhwala ayenera kuchitidwa mankhwala symptomatic.

Mwanjira mankhwala "Dekapeptil" sichinayambe anakhazikitsa wothandizila ena.

lachindunji odwala

mankhwala "Dekapeptil" ayenera kukhala pansi pa ulamuliro okhwima mlingo wa mahomoni kugonana magazi.

Akazi ayenera kugwira kuphunzira kuti kupewa ndi mimba zotheka. Pa ntchito mankhwala amenewa ndi olakwika ntchito kulera m'thupi, komanso kukonzekera munali estrogens palokha.

Wodwala ayenera analangiza kuti m'kati mwa mankhwala ankaona mankhwala kusamba adzakhala kwina.

Kugwiritsa ntchito chida ichi amuna kungayambitse kuwonongeka afika chikhalidwe chawo. ayenera yomweyo dokotala pa zosayembekezereka zizindikiro negative.

mankhwala ofanana

Kodi m'malo njira mankhwala "Dekapeptil"? Analogues kuti mankhwala ndi kovuta kupeza, kotero njira zofanana tiyenera kuchita kokha dokotala wodziwa.

Malinga ndi mawu a akatswiri ena, mankhwala akhoza mwaganizapo m'malo mwa njira zotsatirazi:. 'Zoladex', 'Buserelin Depot "," Diferelin "," triptorelin "

Reviews wa njira jekeseni

Panopa kwa mankhwala a endometriosis, dongosolo ubereki ndi matenda ena kothandiza kwambiri ndi wogwira mtima agonists wa gonadotropin-kumasuka timadzi. Zikuphatikizapo mankhwala monga "Dekapeptil", "Diferelin ',' Zoladex 'ndi ena. Komabe, tisaiwale kuti kukwera mtengo kwa ndalama ngati salola kuti iwo ankagwiritsa ntchito yochizira matenda. Pa nkhani imeneyi, ndemanga pa ntchito zawo, palibe kwambiri.

Malinga ndi malipoti a akatswiri mankhwala "Dekapeptil" nthawi zambiri zotchulidwa zochizira fibroids uterine (nthawi miyezi 5-6). Kugwiritsira ntchito ya medicament chifukwa mu kuchepetsa voliyumu uterine ndi makulidwe a mfundo. Lotsatira opaleshoni. Choncho, mankhwala "Dekapeptilom" anali zotchulidwa monga kukonzekera preoperative.

odwala ambiri kuti pambuyo kumayambiriro njira amachita anamuona jekeseni malo ululu, kuyabwa ndi redness. Komanso mutu, amamva tulo ndi kutopa.

malipoti zabwino za chida kawirikawiri kusiya akazi ntchito "Dekapeptil" lidzawagwiritsenso protocol. Ndiyamika mankhwala nthawi zambiri ndondomeko kukhazikitsa Ndisanaumbidwe m'chiberekero umatha bwinobwino. Mbali zotsatira anatchula fairer kugonana amatuluka otentha ndi thukuta.