Zikuonetsa Ntchito "Metformin": malangizo ndi ndemanga

"Metformin" ndi chida n'kofunika kuti anthu akuvutika shuga. "Metformin Richter" zikuonetsa ntchito amene ali oyenera odwala ambiri ndi shuga, kumathandiza kuchepetsa shuga, kuti tilimbikitse mlingo woyenera wa zimam'patsa kagayidwe, potero utithandize khalidwe la moyo, monga zatsimikiziridwa mwa mayankho ambiri abwino odwala.

Pharmacodynamics ndi Pharmacokinetics

"Metformin" kubweza ndondomeko gluconeogenesis mu chiwindi ndipo akhala chopinga kuchezerana matumbo mu thupi la shuga. Choncho pali kuwongola wa zotumphukira shuga pogawanikana pamawere ndi kuonjezera chiwindi minofu kudziwa insulin. njira awa sali limodzi gipoglemicheskimi zochita wothandizila sikumangotikhudza yopanga zachilengedwe maselo beta a kapamba insulin, mosiyana analogues mankhwala "Metformin".

Zikuonetsa kuti kuwonda mankhwala anaonekera chifukwa umatha ziziyenda kapena kuchepetsa wodwalayo thupi.

Atakhala "Metformin" kwa mundawo m'mimba ayamba kulowa mankhwala yogwira ndi zochita za kumayamba mankhwala pambuyo maola 2-2.5. Mbali yapadera ndi kumatanthauza unlinkability pafupifupi zonsezo plasma.

"Metformin" zingaunjikane mu impso ndi chiwindi, malovu England, akulu zimakhala. Anasonyeza pafupifupi mwathunthu impso pambuyo maola 9-12 pambuyo utsogoleli. Ngati aimpso mtima ntchito akusokoneza njira akhoza kudziunjikira mu thupi kwa nthawi yaitali.

Zizindikiro ndi contraindications

Zikuonetsa Ntchito "Metformin" motere:

• Shuga mtundu 2 kudutsa popanda mtima wofuna ketoacidosis, umene uli wofunika kwambiri odwala matenda ashuga onenepa.
• Mothandizana ndi insulin mu mtundu 2 shuga, kunenepa kulemera, kenako sekondale insulin kukana.

Ngakhale dzuwa mkulu wa mankhwala, pali contraindications kugwiritsa ntchito "Metformin":

• Ketoacidosis mu shuga predkomatoznoe boma kapena chikomokere.
• Wonongeka a impso.
• matenda pachimake, zikubweretsa maonekedwe a impso kukanika - matenda, kuchepa madzi m'thupi ndi matenda otsekula m'mimba kwambiri kapena kusanza, malungo, matenda a dongosolo kupuma, hypoxia.
• Pachimake ndi aakulu matenda, zikubweretsa maonekedwe a minofu hypoxia - mtima kapena kupuma kulephera, pachimake m'mnyewa wamtima infarction.
• Akukonza alowererepo pa opaleshoni, kenako inakonzedwa insulin mankhwala.
• Chiwindi kukanika.
• Pachimake Mowa poizoni, aakulu uchidakwa.
• Mimba.
• Yoyamwitsa.
• Mbali yapadera.

mlingo

Mlingo "Metformin" anatsimikiza zochokera zili shuga magazi ndipo anatumizidwa dokotala kwa wodwala aliyense payekha. Kawirikawiri kuyambira ranges mlingo ku 0,5 1 g / tsiku. (1-2 mapiritsi), kenako, zochokera shuga msinkhu atapita masiku 10-15 phwando zotheka owonjezekera kuwonjezeka mlingo.

The yokonza mlingo "Metformin" ndi 1.5-2.0 g / tsiku. (3-4 mapiritsi), ndi pazipita mlingo - 3,0 g / tsiku. kapena mapiritsi 6. Kwa odwala mu ukalamba mlingo wapamwamba - osapitirira 1.0 g / tsiku. (Mapiritsii 2).

Zikuonetsa Ntchito "Metformin" ndi umboni odwala amati mankhwala ayenera kumwedwa nthawi ya chakudya kapena nthawi yomweyo pambuyo, kumwa madzi opanda. The tsiku mlingo tikulimbikitsidwa kugawanitsa mu Mlingo 2-3 tsiku lonse.

Kuchita ambiri osokoneza

Ambiri osokoneza kungachititse kuti acidosis lactic, amene agonjetsa imfa.

Lactic acidosis amakhala ndi zizindikiro zotsatirazi:

• Chizungulire limodzi ndi kunyansidwa ndi kusanza.
• M'mimba.
• The kuchepa lakuthwa kutentha thupi.
• mofulumira kupuma.
• zowawa lakuthwa mu minofu, pamimba.
• Kuchepa kwa chikumbumtima ndi isanayambike chikomokere.

Pamene osachepera wofatsa zizindikiro za acidosis lactic ayenera yomweyo siyani kumwa mankhwala "Metformin" amayesetsa m'chipatala.

Zothandiza kwambiri achire ntchito pamene hemodialysis ndi lactic acidosis, ndi chithandizo wogwira zizindikiro payekha.

Mwanjira ndi mankhwala ena

Mankhwala "Metformin" zikuonetsa ntchito zomwe amapatula ntchito concomitant mankhwala ndi mankhwala ena sangathe ntchito pamodzi ndi dinazolom chifukwa hyperglycemia yamasika kwenikweni. Ngati ndi kotheka, kumwa mankhwala dinazolom amafunikira kusintha mlingo "Metformin" imene tiyenera kugwira dokotala.

"Metformin" phwando ayenera kusiya kwathunthu kusintha kulikonse mlingo limodzi ndi mankhwala zotsatirazi:

• "Chlorpromazine".
• Neuroleptics.
• Oral kulera, mahomoni a chithokomiro, thiazide ndi kuzungulira okodzetsa.
• "Epinephrine".
• "Cimetidine".

Komanso, pamene anasonyeza ntchito "Metformin" zofunikira kwathunthu kusiya kudya mowa, mwinamwake, kuweruza ndi mayankho odwala, zotsatira achire ali kwambiri yafupika.

"Metformin": ndemanga pamene ntchito kuwonda

zotsatira chimodzi chokha achire si kuchuluka kwa ntchito mankhwala "Metformin". Zikuonetsa ntchito, ndi ndemanga umboni wa luso monga:

• Kuchepetsa shuga magazi.
• Kuchepetsa insulin zachilengedwe, imbaenda kuchepetsa njala.
• Letsani mapangidwe mafuta zimam'patsa mu chiwindi.
• Kuchepetsa mlingo wa kuloŵerera chakudya kulowa thupi ndi chakudya.

Ntchito "Metformin" kuti kuonda ndi ankadziwa kuti ntchito yake chachikulu ndi malo amene pali Tikaganizira za madipoziti mafuta osati minofu minofu. Chifukwa wogwira mtima ndi wowona ku imfa thupi, malinga ndi zambiri maganizo za yokonza odwala onse ndi madokotala, ayenera kulenga zinthu yabwino:

• Kukana ufa lokoma ndi, komanso mayiko zakudya (Zakudyazi, dzinthu, yosenda mbatata).
• Kuchepetsa kadyedwe wa zopatsa mphamvu.
• Yogwira kuchita masewera olimbitsa thupi nthawi zonse.

Pamene ntchito "Metformin" slimming mlingo ayenera kusiya 500 mg / tsiku, ndi kudya ayenera kupatsidwa pamaso nkhomaliro ndi chakudya. Reviews mtima kukonzekera amasonyeza okwanira mphamvu ya pamene akuponya kulemera muyeso, koma ntchito "Metformin" ndendende zolinga izi sikuloledwa popanda kukambirana ndi dokotala ndi dietitian.

zotsatira zoyipazi

Ngakhale zizindikiro lonse ntchito, "metformin" angayambitse ndi chiwonetsero cha zina mwa zizindikiro zosasangalatsa pa mundawo m'mimba, chifukwa mphamvu ya mankhwala:

• Kusanza, nseru.
• Osauka kudya kapena sanamwe.
• Flatulence, kutsekula m'mimba, kupweteka m'mimba.

Nthawi zambiri zizindikiro zimenezi pa chiyambi cha mankhwala ndipo maganizo odwala kutha paokha.

Zotsatira lalikulu kwambiri mbali ku machitidwe ena:

• B12 kuperewera kwa vitamini, ndi lactic acidosis.
• Megaloblastic magazi m'thupi.
• Hypoglycemia.
• Totupa ngati sayanjana.

malangizo Special ntchito, ndi umboni mtima

Ngati mankhwala ena aliwonse ali contraindications ake ndi zizindikiro ntchito, "Metformin" amafunika kumvetsera mwatcheru mlingo ndi nthawi chiphaso.

Makamaka, pa phwando ayenera nthawi zonse kuwunika impso ntchito, umene osachepera kawiri pa chaka, komanso chiwonetsero cha myalgia ndi kudziwa zili lactate mu madzi. Komanso, miyezi sikisi iliyonse ayenera kuunikira mu creatinine seramu, makamaka mu m'badwo wa odwala.

Pamene kulandira "Metformin" osakaniza sulfonylureas n'kofunika nthawi zonse kuwunika mlingo wa shuga m'magazi.

Pamene matenda a dongosolo genitourinary, kapena matenda bronchopulmonary ayenera yomweyo kukanena kwa dokotala.

Mankhwala sikumangotikhudza kuthekera kuyendetsa galimoto ndi sikusokoneza mu ntchito ya zimagwirira.

Kuphatikiza "Metformin" ndi mankhwala ena hypoglycemic kungachititse kuti chitukuko cha zinthu hypoglycemic, yodziwika ndi matenda kukumbukira, omwe amaletsa wotsogolera galimoto ndi kuchita zinthu zina zikanavulaza ndipo amafunika chisamaliro chachikulu ndi anachita.

Mu nthawi ya mankhwala ndi koletsedwa mowa ndi mankhwala okhala ndi Mowa.

Malinga ndi ndemanga za mankhwala "Metformin" ngakhale zotsatira ambiri mantha provleniya mbali zimachitika iwo ali osowa kwambiri, kapena mlingo wochepa. Ndipo okonda kunena makamaka lokoma, pamene kumwa mankhwala n'zotheka kupereka kagawo ya mkate kapena lokoma, ngakhale infrequently.

Komanso mu review patsintov zolemba ashuga ndi kochulukira imabwera kukhala ndi pakati pamene kulandira "Metformin" osati amathandiza kuchotsa matenda, komanso osangalala m'banja.