The bwino kufanizira "cordarone" mu Russian

Chithandizo cha matenda mungoli mtima - zovuta mankhwala vuto si anatsimikiza mpaka mapeto, ngakhale lero. Pali ambiri odana arrhythmic mankhwala, koma ali contraindications ambiri ndi mavuto chifukwa cha zimene ukakhale zoopsa kwambiri pa matenda a wodwalayo. Pali magulu lonse la ndalama anafuna kuti mpumulo wa arrhythmias, a moyo pachiswe, koma ntchito zawo kwa nthawi yaitali ali osavomerezeka chifukwa cha kuwonjezeka chifukwa cha mavuto kulandira mankhwala. Choncho, odwala amafunika odalirika, kothandiza, koma wosavuta mankhwala, kapena analogi zace.

"Kordaron" - wogwira mtima antiarrhythmic mankhwala

Malinga ndi maphunziro osiyanasiyana, "Kordaron" ndi mankhwala zothandiza kwambiri mankhwala ena ofanana, ali ndi luso chotsimikiziridwa kuchepetsa imfa za odwala ndi matenda mtima. Izo ntchito bwinobwino mankhwalawa pafupifupi onse arrhythmias mtima. Madokotala, iye ankaona miyeso yolinganizira kwa odana arrhythmic mankhwala kalasi III. Kuwonjezera ndi antiarrhythmic, antianginal zake ali, kuyambira woyamba unakhazikitsidwa ngati mankhwala zochizira matenda a mitima.

Iwo ali ndi zotsatira khalidwe la kalasi III antiarrhythmics, i.e. anatseka misewu ya njira potassium koma kanthu, khalidwe kalasi Ine mankhwala - pa anatseka misewu ya njira sodium, IV kalasi - anatseka misewu ya njira calcium. Mwa zina, mankhwala amapereka alpha- ndi beta-adrenoceptor Letsani, inatsekeratu dilator kwenikweni.

zikuonetsa

The yogwira pophika mankhwala - amiodarone. Trade dzina - "Cordarone." Analogs opangidwa ndi mayina ena, koma ali yemweyo yogwira mankhwala. Amiodarone amapangidwa mu mawonekedwe a njira jekeseni mtsempha, ndi miyala.

Yankho umagwiritsidwa ntchito choncho pamene kuli kofunikira kuti asiye matenda yamitsempha yamagazi ndi supraventricular tachycardia, matenda fibrillation, kuphatikizapo khunyu. Mapiritsi ntchito kupewa yamitsempha yamagazi ndi arrhythmias matenda ndi paroxysmal tachycardia.

Mfundo ntchito

Poletsa ndondomeko zoyendera okhudza maselo ambiri a ayoni potassium mankhwala prolongs gawo lachitatu la angathe kuchitapo kanthu maselo mtima minofu. Komanso limaleka anamasulira zimachitika magetsi mu misempha ya mfundo atrioventricular. Chifukwa cha ichi, adzionere yekha kubweza. Chifukwa cha zimenezi, a tsankho Letsani zotsatira za mantha dongosolo wachifundo kubweza mlingo mtima.

Amiodarone ndi zimapukusidwa mu chiwindi ndi excreted makamaka mkodzo. Okhutira pazipita thunthu yogwira anati pambuyo maola 3-7 pambuyo ingestion wa phale. Olimbikitsidwa zotsatira achire zikuoneka kale kuposa sabata imodzi pambuyo chiyambi cha mankhwala.

Analogs "cordarone"

Nthawi zambiri, odwala zifukwa zosiyanasiyana amakonda mankhwala oyambirira ndi zofanana ake, generics. Popeza "Kordaron" - chabe malonda dzina la amiodarone, akudwala arrhythmias zambiri ndikudabwa ngati pali mankhwala analogues "Cordarone."

Ponena amiodarone, funso analogues ake makamaka zogwirizana, chifukwa mmodzi wa mankhwala wotchuka kwambiri mu dziko la cardiology, ali ntchito lonse. Mankhwalawa, monga tatchulazi, ndi zotsatira zoyipa zambiri, nthawi zambiri kudwala. Choncho, sing'anga ndi wodwala chidwi ndi kusankha mankhwala ndi dzuwa pazipita ndi chiopsezo osachepera moyo wawo pachiswe. Ngati mukufuna lofanana mankhwala "Kordaron" Anzawo, ndi ndemanga madokotala Pankhaniyi muyenera kukhala pa zovutazi, ngakhale, ndithudi, odwala kwenikweni zili zofunikira, chifukwa ndikhoza kukuuzani inu momwe iwo anamverera pa phwando ndi liwiro isanayambike kusintha. Ndi mankhwala monga "kordaron" kapena aliyense wa analogs ayenera limodzi ndi achipatala ndi kuwunika udindo thanzi, kuphatikizapo mwa ECG ndi.

Umagwira ntchito yofunika komanso zikuchokera mankhwala. Mwachitsanzo, ayodini, gawo la amiodarone ndi contraindicated zingapo za matenda. Ndiponso, tingayambe zotsatira za kafukufuku. N'zosadabwitsa kuti ambiri amavutika arrhythmia kuyang'ana analogue "cordarone" popanda ayodini ngati 'dronedarone. " Kumene, m'malo aliyense mankhwala yekha atakambilana ndi dokotala. Choncho, ambiri akatswiri Russian musati amalangiza kusankha "Dronedarone" poponya, monga ndi ofooka analogi "cordarone". Ku Ulaya, komabe kale ambiri ndithu.

Posankha mankhwala kapena analogi zofunika kuyerekeza zikuchokera awo. Tinganene, ndi zofanana generic si poyerekeza ndi mzake - wokha wapachiyambi. Mwachitsanzo, ngati mukufuna analogi "cordarone" mu ampoules, mu gawo la njira yomweyo jekeseni ayenera kupezeka benzyl mowa, monga pachiyambi "Cordarone."

Monga madokotala kulingalira, osati wolephera katundu wa mankhwala "Kordaron" analogues mu Russia anapereka chiwerengero mwachilungamo lalikulu la mankhwala, monga: "Ritmiodaron", "Sedakoron", "Amiokordin", "Kardiodaron", "Ritmorest", "Opakorden" "Amiodarone" kuchokera opanga osiyana ( "Amiodarone okwana", "Vero Amiodarone" ndi ena ambiri). Onsewo ali yemweyo yogwira pophika, koma akhale nawo excipients osiyana. Ambiri a iwo ali otsika mtengo kuposa choyambirira. Nthawi zambiri, chinthu ichi zimadalira Mlengi. Mwachitsanzo, "Amiodarone", amene dzina lake chimodzimodzi monga thunthu zikuluzikulu zili yokonza "Kordaron". Russian analogue, ndipo mtengo wake ndi pafupifupi katatu m'munsi, ngakhale mawonekedwe likuchita, ndi zizindikiro kwa cholinga chomwecho.

"Amiodoron" - pa analogues bwino mu Russia. Ndi pafupifupi osiyana "cordarone" ndi mfundo kanthu, ndi njira ntchito ali yemweyo mkulu ntchito mu atagwira nkhani fibrillation ndi kupewa asayembekezere. Umboni za izo ku mbali yaikulu positive. Ambiri a iwo amati "Amiodoron" kupanga Russian amathandiza mwamsanga ndipo popanda pobochki lolemera.

Dosing wa mankhwala ampoules

Monga tanena njira jekeseni likuwonetsedwa chithandizo mwamsanga vutoli. ntchito "Kordaron" mapiritsi nthawi zina. Analogs ntchito momwemo. The njira zothanirana ndi mavuto jekeseni kudzera catheter kwa mphindi 20-120 kapena bolus osachepera 3 Mphindi pa mlingo wa 5 mg pa 1 makilogalamu thupi.

N'zimene piritsi "cordarone"

mankhwala atengedwa mu mapiritsi kaŵiri.

Gawo loyamba kapena katundu gawo: 600-800 mg ndi kamodzi tsiku lililonse, kuchuluka kwa 10 g.

Chinthu chachiwiri, kapena gawo yokonza: 100-400 mg wa mankhwala (nthawi anatsimikiza ndi dokotala). Mlingo pazipita 1200 mg wa pa tsiku.

An ambiri osokoneza mankhwala ndi oopsa zokwanira. Pofuna kupewa izi, woleza mtima ndi bwino kudziwa mmene kumwa mankhwala "Kordaron" malangizo Buku. Analogs, kuphatikizapo mnzake otchuka mu Russia "Amiadaron", ambiri a iwo kupereka zizindikiro zomwezo za mankhwala osokoneza bongo.

Pali bradycardia amphamvu, ngakhale mpaka kumangidwa mtima. Ngati chifukwa cha piritsi mawonekedwe, m'pofunika kusambitsana kunja m'mimba ndi kutenga chelators. Imachitikanso ena symptomatic mankhwala, electrolyte bwino kusintha. Ngati ndi kotheka, anapereka pacemaker.

About mtsempha ambiri osokoneza uthenga chosakwanira. Anafotokoza nthawi zina la nkusani bradycardia, tachycardia, mtima kumangidwa. Mankhwala ofanana ndi amene anasonyeza kuti ambiri osokoneza chifukwa cha mankhwala. Hemodialysis amiodarone ndi metabolites ake kuchotsedwa.

zotsatira zoyipazi

Pamene ndi njira iliyonse imayenera kanthu amphamvu, "Kordaron" "Amiodarone" ndi mndandanda zina analogs imfayo zochitika chowawa. Amayambitsa bradycardia mpaka kumangidwa mtima, kuthamanga kwa magazi, ndi zoyipa pa chiwindi, kukhala ndi mndandanda m'malo chidwi cha contraindications.

Kuyambira zochepa aakulu komabe zosasangalatsa mbali-zotsatira Tingaone kupweteka chizungulire, pleurisy, chifuwa, wodwalayo angadandaule za kufooka, kusakhala ndi acuity zithunzi. Zikhoza thupi lawo siligwirizana. Vuto lomwelo akhoza zopezera potenga analogi iliyonse. "Kordaron" ndi zina mapiritsi mankhwala amiodarone chifukwa chimenechi, amagulitsidwa pharmacies yekha ndi mankhwala. A njira jekeseni ntchito kokha chilengedwe chipatala.

Komabe, ndi chisamaliro anatengedwa posankha pazipita mavuto mlingo ali anasonyeza pang'ono kapena ayi kuonekera pa zonse. Monga momwe kupenda "kordaron" ndi "Amiodarone" odwala kumwa mankhwala awa, pobochka zambiri ofooka, mosavuta inathetsedwa ndi kusintha kwa mlingo mankhwala.

contraindications

Popeza amiodarone - mankhwala okongola wamphamvu, n'zosadabwitsa kuti lingathandize kusintha mkhalidwe zingapo za matenda a mtima, koma pa nthawi yomweyo ndi mavuto aakulu pa ziwalo zina kapena chikhalidwe worsens ndi matenda ena concomitant. Kupewa ngozi, osavomerezeka mankhwala ndi mankhwala zina.

Pali mndandanda wa zinthu zomwe akuletsedwa akulandira "Kordaron", "Amiodarone" ndi Akhristu ena miyala. Woyamba ndi ena nthenda mtima - nkusani bradycardia, atrioventricular chipika digiri kwambiri, hypotension, prolongation wa QT imeneyi pa ECG lapansi. Izo sizingakhoze ntchito ngati wodwala ali ayanjane mu thupi zili potaziyamu ndi magnesium.

Contraindications monga chithokomiro matenda, komanso mimba ndi yoyamwitsa - chifukwa ayodini, muli mankhwala "Cordarone." Analogi, osati munali izo, angathe kumwedwa yekha malangizo dokotala.

Odwala okalamba tikulimbikitsidwa kuti kusamala kutengedwa ngati "Kordaron" ndi "Amiodarone" ndi analogs ena. Odwala wamng'ono kuposa zaka 18, mankhwala osankhidwa.

Kodi sanasankhe njira amene amadwala mphumu bronchial, kulephera kupuma, kuzimwera mtima kulephera. Aakulu chiwindi matenda ndi impso - komanso chifukwa kukana chithandizo mwa njira imeneyi.

Mosakayikira, sitiyenera kutenga mankhwala ngati pali tsankho munthuyo zigawo zikuluzikulu za mankhwala "Cordarone." Analogues ku Russia ndi m'mayiko ena ku Ulaya ndi zikuchokera chomwecho, choncho ichi m'malo wothandizila ena chimodzi chodziwikiratu kuti apambane.

Pankhani jakisoni, sangathe kupanga ana osaposa zaka 3, kwa ana okulirapo kuposa zaka 3, mlingo sayenera upambana 5 mg / kg. Sizimayenderana mankhwala mu syringe chomwecho ndi mankhwala ena. Ambiri, contraindications ndi njira zofanana ndi contraindications kuti miyala. Izi bradycardia nkusani, odwala nkusani syndrome ndi matenda aakulu conduction, monga sinoatrial chipika mitima ndi tachycardia paroxysmal yamitsempha yamagazi. Makamaka, zochitika ngati n'zotheka pamene mukumwa amiodarone limodzi ndi mankhwala ena.

Jakisoni pa mimba ndi zotheka milandu kwapadera, pamene mkaka wa m'mawere ndi njira mankhwala kwathunthu mulibemo. N'zosatheka kuchita mankhwala ntchito "cordarone" njira ndi chithokomiro kukanika, thupi lawo siligwirizana ndi ayodini kapena amiodarone.

Mogwirizana ndi mankhwala ena

"Kordaron" akhoza pamodzi ndi mankhwala ena. Choncho, zotsatira zake antianginal kumatheka limodzi ndi mankhwala nitrate kanthu yaitali. Thiabendazole angagwiritsidwe ntchito molumikizana ndi anticoagulants, okodzetsa, mankhwala cardiotonic, musati kucheza ndipo motero, musati kufooketsa kapena kulimbikitsa zotsatira za aliyense "Kordaron" ndi zina neuroleptics zina, analgesics, hypnotics ndi mankhwala. Pafupifupi kumva mankhwala analogi iliyonse.

"Kordaron" sangathe ntchito imodzi ndi Mao zoletsa ndi beta-blockers (milandu kwapadera okha).

CHENJEZO zochepetsera "kordaron" ndi "Amiodarone"

Pa phwando njira izi amafuna polojekiti chikhalidwe thupi isanafike mankhwala, pamene kenako.

Isanayambe ndiponso ili m'kati mankhwala piritsi mawonekedwe kugwira ECG bwino. Mmene mankhwala amachititsa kusintha electrocardiogram ndi, makamaka, prolongation wa imeneyi T ndi Q-Q-T. Potsatira zotsatira za kumupima adokotala akhoza kusintha mlingo ndi kudziwa mphamvu ya mankhwala.

Chithandizocho kutsazikana pamene osauka atrioventricular chipika II ndi III digiri sinoatrialnaya, intraventricular ziwiri mtengo.

Popeza imodzi mwa zigawo zikuluzikulu za mankhwala ndi ayodini, amafuna polojekiti zonse ntchito chithokomiro. Pamaso mankhwala n'kofunika kudziwa mlingo wa mahomoni T3, T4 ndi TSH. Chonde dziwani kuti pa maziko a "cordarone" maphunziro a chithokomiro radioisotope akhoza kukhala osadalirika. Pa timadzi ta m'thupi ayodini sikumangotikhudza deta.

Chinthu china chofunika ndi kudziwa mlingo wa potaziyamu mu seramu magazi mankhwala ndi pa izo.

Pamene kutumikiridwa "cordarone" analimbikitsa mtsempha kulowetsedwa kokha, osati syringe jekeseni. Apo ayi, mwina chitukuko cha matenda hemodynamic - wolumikizira hypotension, pachimake mtima insufficiency. Syringe kubaya mankhwala okha mavuto aakulu mwadzidzidzi, pakalibe mwayi wina. Pankhaniyi mlingo 5 mg / kg ndipo wapezeka kwa mphindi zitatu, kukonzanso - palibe mwansanga koposa Mphindi 15 pambuyo utsogoleli choyamba. ndondomeko angathe kuchitidwa kokha m'madipatimenti chisamaliro inatsekeratu kuyang'aniridwa ndi ECG lapansi. "Kordaron" osati kusakaniza mu syringe ndi mankhwala ena. Ngati muli ndi mankhwala yaitali chofunika kupita kulowetsedwa lapansi. Aliyense amiodarone mtsempha ikuchitika mu zipatala.

Ngati wodwalayo ndi mankhwala ochititsa zambiri, anesthetist ayenera analangiza kuti kutenga mankhwala.

Kupewa mavuto, odwala ayenera kutsatira mlingo malangizo a dokotala.

Pa mankhwala, odwala ayenera kupewa dzuwa ndi ntchito chitetezo izo (kuphatikizapo creams wapadera), ngati kuli kofunika.

Onetsetsani kuti kulankhula ndi dokotala, ngati pazifukwa zina sitikufuna kuti titenge "Kordaron" ndi mnzake ake. "Kordaron" ndi mankhwala ofanana ndi Iye, monga mankhwala ena aliwonse mtima zikhoza kukhala zoopsa kwambiri ngati phwando kusalankhula. Only dokotala akhoza kudziwa mankhwala zingakhale bwino vuto lanu ndi adzasankha sefa, koma ogwira mlingo.