"Pulogalamu": Buku lophunzitsira, ndemanga

Kuthamanga kumatanthawuza mphuno (reflex) ya zomwe zili m'mimba kudzera m'kamwa. Kawirikawiri izi zimayambitsidwa ndi kusungulumwa, komanso kumeza kayendetsedwe kazinthu zopanda chidwi, kuwonjezeka kwa misonzi, misozi komanso kupuma mofulumira.

Kuphatikizana ndi zakudya zowonongeka, madzi a mimba, ntchentche, bile ndi zinthu zina zosafunika, anthu amapuma komanso zinthu zothandiza. Izi zingayambitse kusokonezeka kwa madzi ndi kutentha kwa electrolyte. Choncho, ndi kusanza mwamphamvu ndi kawirikawiri, m'pofunika kutenga zingapo zomwe zingasunge mchere ndi zinthu zina m'thupi la munthu.

Imodzi mwa mankhwala otchuka kwambiri oyambitsa antimetic ndi "Motionium." Malangizo ogwiritsiridwa ntchito, ndemanga, katundu ndi zovomerezeka za mankhwala awa zanenedwa pansipa.

Kuwongolera kwa mankhwala, mawonekedwe ake, ma phukusi ndi kufotokoza

Kodi makonzedwe opangidwa ndi Motonium ndi otani? Malangizowo amavomereza kuti wothandizirawa amapangidwa ndi mawonekedwe a mapiritsi oyandikana ndi oyera. Zosakaniza zawo ndi domperidone. Mankhwalawa akuphatikizapo: lactose, microcrystalline cellulose, glycerol, starch chimanga, magnesium stearate ndi low molecular weight povidone. Koma pamwamba pa chipolopolo, chimapangidwa ndi hydroxypropyl methylcellulose ndi polyethylene glycol 6000.

Kugula mapiritsi "Motionium" (kuchokera pa zomwe asankhidwa, tidzanena pansipa) ndi zotheka m'mabulters kapena zitini za polima, zitanyamula mu mapaketi makatoni.

Mankhwala othandiza

Kodi mankhwala osokoneza bongo amagwira ntchito bwanji? Malangizo ogwiritsira ntchito amasonyeza kuti chida ichi chikuwonjezereka kuchuluka kwa zowonongeka za zowonongeka m'mimba ndi m'mimba. Kuonjezera apo, imathamanga kwambiri kutaya mimba (pang'onopang'ono), kumathetsa kunyoza ndi kusanza, komanso kumatulutsa mawu a esophageal sphincter (m'munsi).

Ndichinthu china chodabwitsa chotani cha mankhwalawa "Motion"? Ndemanga zimasonyeza kuti zimathandizira kutulutsidwa kwa prolactin ku nthenda ya pituitary. Mphamvu zake zowonongeka zimachokera ku zowona kapena zoopsa zapadera, kuphatikizapo kutsutsana kwa mapulogalamu a dopamine omwe ali m'dera la chimoreceptor trigger zone.

Tiyeneranso kukumbukira kuti domperidone sichigwira ntchito yotsekemera ya mimba ya mimba.

Zinthu zachikondi

Ndi mtundu wanji wa kinetics ndi khalidwe la mankhwala ngati "Kutsitsimula"? Malangizo ogwiritsira ntchito amanena kuti atatha kumwa mankhwala, amamwa mofulumira.

Mankhwalawa ali ndi chidziwitso chochepa (pafupifupi 15%). Nthenda yake yaikulu m'magazi imatha pambuyo pa mphindi 60.

Kuchepetsa acidity wa chapamimba madzi kumachepetsa kuyamwa kwa domperidone. Amalowa molakwika kupyolera mu BBB, choncho ntchito yake imakhala yochepa kwambiri.

Mankhwala a "Motionium", malangizo omwe amagwiritsidwa ntchito m'munsimu, amagawidwa bwino pakati pa ziwalozo. Komabe, kuika maganizo mu ubongo sikungatheke. The kumangiriza kwa mankhwala kwa plasma mapuloteni ndi 91-92%.

Mankhwalawa amadziwika kwambiri m'chiwindi ndi m'mimba. Nthaŵi ya kuthetsa kwace ndi maola 9, ndipo ngati chiwerengero cha nthendayi sichikwanira (nthawiyi) ndi yaitali.

Mankhwala amaperekedwa ndi impso komanso kudzera m'matumbo.

Zizindikiro za kumwa mapiritsi a mankhwala

Kodi ndi nthawi ziti zomwe wodwalayo angapemphere mankhwala oti "Motionium"? Malingaliro a madokotala akuti mankhwalawa amagwiritsidwa ntchito mu zovuta za zizindikiro zoopsa zomwe zimagwirizanitsidwa ndi mimba ya m'mimba kapena kuchepa kwa m'mimba, kuchedwa kwa msangamsanga kutaya kapena kupweteka kwa m'mimba. Choncho, wogwiritsira ntchitoyo akugwiritsidwa ntchito mu flatulence, kusefukira kumverera mu chigawo cha epigastric, kumimba kwa mimba, kupweteka, kupweteka kwa m'mimba, ndi kupweteka kwa mtima popanda kuponyedwa (kapena, kuponyera, kuponyera) zomwe zili m'mimba kubwerera mkamwa.

Nchiyani chinanso chomwe chimathandiza mankhwala "Motion"? Malangizo ogwiritsira ntchito amatiuza kuti mankhwalawa amachititsa kuti munthu asamve nsanje, amaletsa kukula kwa kusanza kwa mankhwala, matenda opatsirana komanso opatsirana, komanso chifukwa cha radiotherapy, matenda odwala, mankhwala osokoneza bongo komanso agonist (monga bromocriptine kapena levodopa).

Kusiyanitsa kwa kumwa mankhwala

Mankhwalawa amalimbikitsidwa mosamala kwa anthu omwe ali ndi vuto lopanda mphamvu. Kuwonjezera apo, sikuti amauzidwa kuti azipatsanso mimba kapena m'mimba, kutulutsa magazi, kupweteka kwa m'mimba kapena m'mimba, kutsekemera kwa m'mimba, komanso pamaso pa prolactinoma komanso ali ndi zaka zisanu.

Kukonzekera "Motionium": malangizo othandizira

Tengani mankhwalawa ayenera kukhala mkati kwa mphindi 20-35 musanadye chakudya. Mlingo wa mankhwalawa umadalira mkhalidwe wa wodwalayo.

Pa matenda aakulu, ana omwe ali ndi zaka zisanu amalamulidwa mankhwala pa 2.5 mg / 10 kg wolemera thupi katatu patsiku. Ngati mukufunikira kwambiri mankhwalawa amatengedwa musanagone. Kwa akuluakulu, amalembedwa 10 mg mankhwala (kutanthauza piritsi 1) katatu pa tsiku ndipo, ngati kuli kofunikira, asanayambe kugona.

Ngati ndizofunika, mlingo umenewu ukhoza kuwirikiza kawiri.

Muzovuta komanso zosautsa (odzudzula ndi kusanza), odwala akulu amapatsidwa 20 mg ya mankhwala (ie, mapiritsi 2) kanayi patsiku komanso pogona. Kwa ana a zaka zisanu, mankhwalawa akulimbikitsidwa kutenga 5 mg / 10 kg kulemera kwake katatu patsiku ndi pogona.

Zovuta zochitika

Mankhwala odana ndi matendawa amachititsa kuti anthu asamayende bwino. Pali zochitika za m'mimba zochepa za m'mimba, komanso zovuta za extrapyramidal kwa ana ndi anthu omwe ali ndi chiwerengero chokwanira cha BBB.

Kuwonjezera pamenepo, motsutsana ndi kumwa mankhwalawa, zowonongeka monga ming'oma ndi zikopa za khungu zingayambe. Nthawi zina mankhwalawa amachititsa hyperprolactinemia (galactorrhea ndi gynecomastia).

Kuwonjezera pa mankhwala

Kodi zizindikiro ndi chiyani pamene mutenga mlingo waukulu wa mankhwalawa? Akatswiri amanena kuti mankhwalawa angayambitse kugona, kuchitapo kanthu extrapyramidal ndi kusokonezeka, makamaka kwa ana.

Kuti athetse vutoli, wofunsidwayo akulamula kuti azitentha makala ndi antihistamines. Ngati zotsatira za extrapyramidal zikuchitika, wodwalayo angakhale woyenera kutsutsa antiinslinicic agents.

Kuyanjana ndi njira zina

Mankhwala oletsa anticholinergic amachepetsa mphamvu ya domperidone.

Sodium bicarbonate, "Cimetidine" ndi antisecretory, komanso antacid agents, amachepetsa kugwiritsidwa ntchito kwa mankhwalawa.

Maantibayotiki a gulu la mankhwala osokoneza bongo, mankhwala osokoneza bongo, Nefazodone ndi HIV protease inhibitors amachulukitsa mphamvu ya domperidone m'magazi.

Gwiritsani ntchito amayi omwe ali ndi pakati ndi omwe akulera

Mankhwalawa "Motionium" angathe kuikidwa m'miyezi itatu yoyamba ya mimba, koma pazizindikiro zenizeni.

Mu mkaka wa amayi, chiwerengero cha domperidone ndi chocheperachepera kanayi kuposa plasma. Akatswiri samadziwa ngati domperidone yambirimbiri imakhudza ana obadwa kumene. Choncho, mukamamwa mapiritsi, kuyamwitsa kuyenera kutayika.

Malangizo apadera

Anthu omwe ali ndi vuto lalikulu la kupweteka kwa mphutsi, theka la moyo wa mankhwalawa lawonjezeka kuchokera pa maola 9 mpaka 20. Komabe, kumwa mankhwalawa mwazi ndi kochepa kwambiri kusiyana ndi anthu abwinobwino.

Poona kuti mankhwalawa amatulutsidwa ndi impso pang'onopang'ono, kukonza mlingo umodzi wokha kwa odwala omwe ali ndi vuto losafuna chiberekero silofunikira. Komabe, ngati mankhwalawa akubwerezedwa, kuchulukitsa kwake kuyenera kuchepetsedwa kangapo patsiku (kumadalira mlingo wosakwanira).

Ndi mankhwala apanthaŵi yaitali, odwala ayenera kuyang'aniridwa nthawi zonse.

Zosungiramo zosungiramo ndi zofunikira za kundende

Mankhwala omwe ali mu funso ayenela kusungidwa pamalo ouma, otetezedwa ku kuwala, komanso osakwanira ana. Kutentha kwa kusungirako sikuyenera kukhala pamwamba madigiri 25.

Moyo wamtundu wa mankhwala awa ndi miyezi 24. Musamamwe mapiritsi pambuyo pa kutha kwa nthawi yomwe ili pa phukusi.

"Motionium": ndemanga ya odwala

Pali ndemanga zambiri za malo omwe mukufunsidwa. Nthawi zambiri amakhala abwino. Ogulitsa akuti mankhwalawa amachepetsa kusanza ndikuchotsa chisokonezo. Komanso, mankhwalawa amagwiritsidwa ntchito kuchepetsa zizindikiro za matenda.

Kuphatikiza pa kulemera kwabwino, zoyenera za mankhwalawa zikuphatikizapo kusowa kwa kutsutsana kwakukulu ndi kupezeka. Tiyeneranso kukumbukira kuti mankhwala "Motionium" samayambitsa mavuto, kuphatikizapo ana oposa zaka zisanu.