"Mesakol": malangizo ntchito, Akhristu enieni

Anam'peza matenda a m'matumbo ndi matenda amene amatupitsa ali anaona odwala ndi osowa kwambiri. Koma, ngakhale, pali mankhwala ambiri amene anafuna zochizira matenda amenewa. Mmodzi wa iwo ndi "Mesakol". Malangizo ntchito, maonekedwe, zotsatilazi, ndipo mtengo wa ndalama adzakhala anapereka m'munsimu.

The zikuchokera, amasulidwe mawonekedwe, ma CD ndi kufotokozera

Mankhwala "Mesakol", ndemanga zimene ziri osokoneza kwambiri khalidwe, akupitiriza zogulitsa monga miyala red-bulauni. Iwo enteric-lokutidwa ndi kukhala zozungulira ndipo lenticular mawonekedwe.

Thunthu chachikulu cha chida mutuluka mesalazine (5-ASA). Ndi kuwonjezerapo mankhwala monga zigawo zina monga chimanga wowuma, calcium mankwala dihydrate, talc ayeretsedwe, microcrystalline mapadi, titaniyamu oxide hypromellose 2208, silika colloid, povidone K90, sodium carboxymethyl wowuma, ndi copolymer asidi methacrylic ndi methyl methacrylate, okusayidi wofiira chitsulo, macrogol 6000 ndi dibutyl phthalate.

Miyala "Mesakol" chopangidwa mu n'kupanga zotayidwa ndi makatoni mapaketi motero.

mankhwala

Kodi mukudziwa kuti ndi mankhwala "Mesakol"? Malangizo ntchito amasonyeza kuti odana ndi yotupa wothandizira, zotsatira za zomwe isanafalikire mu intestine lapansi. Izi chuma cha medicament chifukwa umatha ziletsa kaphatikizidwe leukotrienes ndi prostaglandins, ndi neutrophil lipoxygenase.

Tiyenera kuona kuti mankhwala ankaona kubweza kusamuka, phagocytosis ndi degranulation wa neutrophils, komanso immunoglobulin katulutsidwe ndi lymphocytes.

katundu Kodi ena ali ndi mankhwala "Mesakol", mtengo wa chomwe chili m'munsimu? Mesalazine kugwira ntchito antimicrobial ndi ena cocci ndi Escherichia coli (mu m'matumbo).

Pharmacokinetics

Kodi chibadidwe kayendedwe magawo mapiritsi "Mesakol"? Malangizo ntchito limanena kuti pambuyo makonzedwe mesalazine adzamasulidwa ku chipolopolo pambuyo pa 115-165 Mphindi, ndipo patapita mphindi 170-230 mapiritsi kupasuka.

Chifukwa kuganizira mankhwala filimu TACHIMATA pa 60-80% adzamasulidwa ku m'mimba, ndipo 15-30% - mu intestine yaing'ono. Pankhaniyi mankhwala yogwira umalandira makope zokhudza zonse yekha mu kuchuluka kwa 10% ya mlingo. Mesalazine ndende mu madzi ndi otsika.

Kulankhulana kwa pophika yogwira ntchito mapuloteni plasma ndi 43%. Akuti mankhwala ndi metabolites ake mu mkaka wa m'mawere.

Kagayidwe mesalazine anachita mu intestine ndi chiwindi. Ici ulikubala N-acetyl-5-aminosalicylic acid.

Hafu ya moyo wa mphindi 60-120 (malingana mlingo). Anasonyeza mankhwala impso ndi kudzera matumbo.

Zikuonetsa kuti alandire mankhwala othandiza

Amene amachitira matenda a mankhwala "Mesakol"? Reviews madokotala amanena kuti chida ichi bwino ndithu kumaonekera matenda amene amatupitsa ndipo anam'peza matenda a m'matumbo.

Tikumbukenso kuti medicament ankaona ntchito osati mankhwala matenda zatchulidwazi komanso kupewa exacerbations.

Contraindications mankhwala

Prescribers "Mesakol" osavomerezeka:

• mu chironda chachikulu cha dongosolo m'mimba;
• matenda magazi;
• aakulu aimpso insufficiency;
• hemorrhagic diathesis;
• paubwana;
• aakulu kwa chiwindi kuwonongeka;
• hypersensitivity kuti popanga mankhwala;
• kusowa kwa shuga-6-mankwala dehydrogenase.

Mosamala mankhwala ntchito wofatsa chowongolera kusalekerera kulephera aimpso, komanso zolimbitsa ndi wofatsa kwa chiwindi insufficiency.

Miyala "Mesakol": malangizo ntchito

Wa ndalama anatengedwa pakamwa chabe pambuyo chakudya.

Pa exacerbation la matenda ndi kutumikiridwa mu kuchuluka kwa 400-800 mg (i.e., mapiritsi 1-2) katatu patsiku. chithandizocho ikuchitika kwa masabata 9-12.

Pakuti kupewa exacerbations ntchito mankhwala ndi 400 mg katatu patsiku. miyala yambiri mu mawonekedwe a, kumwa madzi wamba.

Kodi ana mankhwala "Mesakol"? Makandulo, microclysters ndi kuyimitsidwa - mu mawonekedwe kukuonetsedwa mankhwala kwa ana.

zosiyanasiyana chokhwima

Mwatsoka, kumwa mankhwala ankaona nthawi zambiri amayambitsa zotsatira zina zoyipa. Zikuphatikizapo zotsatirazi:

• pericarditis, tachycardia, mtima conduction matenda, matenda oopsa, kupweteka m'chifuwa, hypotension, palpitations, kufupika kwa mpweya;
• nseru, utachepa kudya, kusanza, kuwonjezeka transaminases chiwindi, kutentha, stomatitis, kutsekula m'mimba, matenda a chiwindi, kupweteka m'mimba, kapamba, pakamwa youma;
• oliguria, proteinuria, crystalluria, hematuria, nephrotic syndrome, anuria;
• chizungulire, kupweteka kwa mutu, kuyerekezera zinthu m'maganizo, tinnitus tulo, polyneuropathy, khunyu, kugwedeza, maganizo;
• eosinophilia, thrombocytopenia, magazi m'thupi (haemolytic, aplastic, kapena megaloblastic), agranulocytosis, kuchepa magazi, hypoprothrombinemia;
• oligospermia, kusabala;
• kufooka, photosensitivity, mumps, kuchepetsa kupanga madzimadzi misozi, lupus-monga matenda, alopecia;
• totupa pakhungu, dermatitis, pruritus, bronchospasm, erythema.

Zizindikiro cha mankhwala osokoneza bongo

Zizindikiro ambiri osokoneza ankaona njira protrude zinthu monga nseru, gastralgia, kusanza, kugona ndi kufooka. Kuthetsa Kwalamulidwa chapamimba lavage, Mankhwalawa ndi mankhwala symptomatic.

Ngakhale ndi mankhwala ena

Mankhwala "Mesakol" amachepetsa zotsatira za "spironolactone" "Furosemide", "rifampicin" ndi sulfonamides. Komanso timapitiriza zotsatira hypoglycemic wa zotumphukira sulfonylurea, ndi kawopsedwe wa methotrexate ndi corticosteroids ulzerogennosti.

Tikumbukenso kuti mankhwala kubweza mayamwidwe wa cyanocobalamin komanso kumawonjezera zotsatira za wothandizila uricosuric (ie, blockers tubular katulutsidwe) ndipo umatithandiza zotsatira za anticoagulants.

ayamikira yeniyeni

• M'mimba zikuchitika pa chithandizo "Mesakolom" sikuti mtima mbali zotsatira za mankhwala. Chotero chikhalidwe akhoza kukhala chizindikiro cha matenda chimapangitsa.
• Pa phwando, chida ayenera nthawi zonse ikuchitika magazi ndi mkodzo mayesero ofanana.
• Ngati mlingo anali ataphonya, zotsatirazi ayenera kumwedwa pa nthawi ina iliyonse.
• Pa mankhwala ndi mankhwala ndi wodwala mkodzo kuichotsa madzimadzi akhoza akuda mu mtundu wachikasu-lalanje.

Mankhwala "Mesakol": Anzawo ndi mtengo

M'malo mankhwala anati akhoza kudzera monga "salazopiridazina", "5-ASA", "Tidokol" "Asacol", "Samezil", "salofalk", "Mesalazine", "Salozinal", "pentasil".

Mochuluka bwanji ndi "Mesakol" piritsi? Mtengo wa mankhwala ndi 600-680 rubles (mapiritsi 50).

ndemanga ogula

Odwala kusiya "Mesakol" kukonzekera ndi wosanganiza kwambiri ndemanga. Ena mwa iwo inanena kuti mankhwala bwino amachitira matenda matumbo. Ena amati mankhwala awa amakhala opanda ntchito. Choncho, tikhoza kunena motsimikiza kuti "Mesakol" mavuto osiyanasiyana pa odwala osiyana.

The drawback waukulu wa mankhwala ndi ambiri contraindications ndi zochita chowawa.