Mankhwala "Tamsulosin": malangizo ntchito, mtengo, ndemanga ndi analogues

"Tamsulosin" antidizuricescoe ndi kanthu mankhwala ndi ntchito monga symptomatic mkodzo modulator ndondomeko matenda Urological chifukwa cha selo zilonda Prostate zotupa khalidwe. limagwirira zimene chimaoneka ndi kuchepa pang'onopang'ono mwamphamvu mu mnofu yosalala prostate, komanso zosangalatsa za khosi chikhodzodzo. Komanso pali kusankha kutsekereza urethral Alpha 1a-adrenretseptorov, chifukwa mu minimization zotsatira anati kutsekeka - zotsatira zachibadwa za chitukuko cha adenomas.

mbali pharmacological a "Tamsulosin"

Mayamwidwe mankhwala yogwira zosakaniza kapepala kakuti m'mimba kungakhale kwa 100%. Experimentally anatsimikizira kuti mayamwidwe ndi chinawonjezeka pamene mukumwa makapisozi yomweyo pambuyo chakudya. Mlingo wa kuloŵerera njila kwa nthawi yadutsa kuyambira kumwa mankhwala (i.e., pali kinetics liniya). Pachimake ndende wa reactants mu madzi ndi Chikupindulidwa pambuyo maola asanu ndi limodzi (single mlingo 400 mg). Komabe, nthawi imeneyi zingasiyane malingana ndi zaka za wodwalayo.

Iwo ananena kuti phwando pa moyo wa masiku asanu, ndende ya zigawo zikuluzikulu mu kuwonjezeka plasma ndi 60-70%. Tamsulosin hydrochloride mokwanira pang'onopang'ono akulowa njira kagayidwe kachakudya: kutengedwa limodzi ndi mapangidwe metabolites khola amene mkulu selectivity kwa Alpha 1a-adrenoceptor.

zikuonetsa

Mankhwala "Tamsulosin" malangizo Buku m'gulu ngati wothandizila zochizira otchedwa benign prostatic hyperplasia, symptomatic aakulu (adenoma, dysuria, ndi ena m'munsi maliseche matenda thirakiti).

Popeza maphunziro matenda sitinawulule zomwe zochita iliyonse yapadera zinthu zina za anati gulu mankhwala, ndiye palibe yosaloledwa ntchito "tamsulosin" monga chothandizira wothandiza ndi mankhwala kutsekereza kusankha alpha-1a adrenergic cholandilira.

Analimbikitsa mlingo ndi njira ya utsogoleli

Chosowa zotsatira hypotensive - Mbali khalidwe la mankhwala "Tamsulosin". Malangizo ntchito limati kuti kufunika kusankha mlingo si - mokwanira pakamwa kutumikiridwa 400 micrograms mankhwala pambuyo chakudya (2 makapisozi / mapiritsi masekeli mg ndi 200, kapena 1 kapisozi / piritsi masekeli 400 mg). Ndiponso zimenezi mtengo tsiku sayenera kudzudzulidwa, ngakhale wodwalayo waona zolakwika zazing'ono mu impso kapena chiwindi. Komabe, chiyambi cha Inde achire ayenera yoyamba ndi matenda enieni kuti amapatula kuthekera kansa ya prostate. Komanso konse mu nthawi ya mankhwala ndi kuvomerezedwa thumbo bwino.

Makapisozi ndi miyala "tamsulosin" sayenera kutafuna - kuphwanya envelopu ndi zingathe kusokoneza mlingo kutulutsidwa kwa reagents yogwira. Chikadzangotha kutenga mankhwala tikulimbikitsidwa kumwa madzi. Izo kutiletsa ntchito "Tamsulosin" mu malo supine.

Alipo zofooka ndi contraindications

Mankhwala "Tamsulosin", mtengo umene, malingana ndi Mlengi ndi ma CD akamagwiritsa, Mitandadza 400-1700 rubles, cholinga yekha kwa anthu. Choncho, kafukufuku zotsatira zake pa mwana wosabadwayo sizinachitike imachitika pa mimba. mankhwala okha amaperekedwa kwa deta piritsi, ndi, matenda a "otchedwa benign prostatic hyperplasia" chiyenera kuikidwa kafukufukuyu (ndi kuvomerezedwa chisanadze mayeso khansa).

Pakati contra - hypersensitivity kwa "Tamsulosin" mankhwala (wogwiritsa ntchito lili ndi mndandanda mwatsatanetsatane za reagents onse wothandiza). Ndi osafunika ntchito ya anati wothandizila kwa orthostatic hypotension ndi matenda aakulu a chiwindi kapena impso (mu Zikatero, dokotala ayenera amanena ubwino angathe kugwiritsa ntchito "tamsulosin" ndi kudziwa mmene zotheka mavuto obwera chifukwa cha Inde achire).

Ndi zonse phwando chovomerezeka kuwala chizungulire, nthawi zina m'malo boma semiconscious. Madalaivala a magalimoto ndi antchito, amene ntchito akatswiri zikukhudza kuopseza kuvulazidwa, ayenera kusunga kusamala kwambiri mu ntchito ya thunthu.

zotsatira zoyipazi

Monga mankhwala ena aliwonse, pali mavuto ndi mankhwala "Tamsulosin" (mtengo wa thanzi amuna ndi lalitali, thupi lawo siligwirizana ndi zazing'ono, kotero kuti zochita chowawa sankaoneka ngati kupanda chidwi cha si koyenera).

Limodzi ndi mmene machiritso zichitike:

• mutu;
• mkwiyo wa khungu;
• Kutalika kwa m'mimba;
• mtima arrhythmias;
• m'chiuno ululu.

"Tamsulosin" Nthawi zina, analogues amene ali m'zinenero pa msika, kuchititsa tulo odwala kapena, Tikawonetsetsa kwambiri tulo. Nthawi zina - kuphwanya zosakhalitsa mpando ndi chifooke potency.

Ambiri osokoneza, mawonetseredwe ake ndi neutralization

Zizindikiro cha mankhwala osokoneza bongo, amene wakhala zotsatira za mankhwala ndi "Tamsulosin" (malangizo ntchito kuchenjeza za izi), akhoza kutchulidwa pachimake hypotension. Ndipo ngakhale imabwera chitsanzo ichi ndi otsika kwambiri, ndi aligorivimu kuthandiza koma anapanga:

• pomwepo wodwalayo malo yopingasa;
• ngati n'koyenera, achite zovuta kwa njira umalimbana ndi normalization wa dongosolo mtima wa thupi;
• kutsimikizira ntchito za impso (kugwirizana zida za yokumba kuyeretsedwa magazi kosathandiza chifukwa pophika yogwira mwangwiro kugwirizana ndi mankhwala plasma mapuloteni);
• asanze wodwalayo kuti asiye mayamwidwe zina za reactants (zowona chapamimba lavage ndi ntchito yomweyi Mankhwalawa);
• pakalibe mphamvu ya kusintha kugwiritsa ntchito mankhwala kuti Zimachititsa magazi.

Mwanjira mankhwala: chikhalidwe cha zochita

"Warfarin" ndi "Diclofenac" qualitatively bwanji linanena bungwe liwiro "Tamsulosin" mankhwala thupi (mtengo mankhwala ndithu, koma zotsatira n'kosathandiza). Komabe, kuzipenya yaitali za ntchito anzake a mankhwala kuchipatala si wonyamulidwa, monga Motero, kusamala kwambiri bwino. "Atenolol" ndi "Enalapril" Kodi si kucheza ndi anati chuma, "cimetidine" amalimbikitsa ndende "tamsulosin" plasma, ndi "Furosemide" amapereka chifukwa kwathunthu zosiyana.

The ndondomeko ya kutsitsa magazi chikwiyire ndi madyedwe a medicament mwina kumatheka chifukwa cha ntchito pamlandu ena alpha-1a adrenoblokatorovv kapena okodzetsa ndi dzanzi. zotsatira chidwi pa kinetics pharmacological ufulu tuzigawo twa "ntchito diazepam" ndi "chlormadinone" ndi kukonzekera "Tamsulosin" malangizo Buku (mtengo pamwamba njira -. 500-1400 opaka) sali kumatanthauza.

zinthu yosungirako ndi moyo alumali

Pa zinthu kusungiramo mankhwala "Tamsulosin" mtsogoleri limati zotsatirazi:

• otetezedwa kutentha osiyanasiyana - 15-25 madigiri Celsius;
• akadakwanitsira chinyezi - 70%.

Chofunika ndi chuma yosungirako mu CD pachiyambi (mu malo kuwerengedwa ana, amene bwino kutetezedwa ku dzuwa).

Pamene mfundo zonse malangizo wopanga ukutitsimikizira kuti zotsatira achire "Tamsulosin" sadzakhala maganizo zaka ziwiri kuchokera pa kumasulidwa ake.

Mankhwala analogues "Tamsulosin"

Mndandanda wa "awiriawiri" ukufanizidwa ndi magulu awiri a mankhwala. Gulu loyamba zikuphatikizapo mankhwala, wamba, wachiwiri - maina malonda osowa.

Ndalama za boma;

• "Omnic" (oyambirira - Omnic), sewerolo - Netherlands, amasulidwe mawonekedwe - mapiritsi / makapisozi zidutswa 10/30 pa paketi, mtengo osiyanasiyana - 380-1700 rubles.
• "Proflosin" (Proflosin), Germany, matuza a makapisozi 30, pafupifupi mtengo - 500 rubles.
• "Sonizin" (Sonizin), DZIKO - Romania, muyezo phukusi la makapisozi 10 kapena 30, mtengo pafupifupi - 450 rubles.

Other zizindikiro zotetezedwa ndi maina malonda a mankhwala "Tamsulosin" (analogs kuti sakhala wamba kapena kumasula mitundu kale kuchotsedwa kupanga):

• "Omsulozin" (Omsulosin), India, makapisozi 0.4 mg (30 ma PC.) Ranges Price kuchokera 350 mpaka rubles 550.
• "Tamsulosin-Teva" (Tamsulosin-TEVA), "Tamara-Actavis" kampani mankhwala, Greece, ndi mawonekedwe a ma CD ndi mtengo ndi chimodzimodzi mu nkhani yapita.
• "Tamsulosin-achigonjetse" ( "understudy" chosunga kumasulidwa chigawo), mzere ulimi anakakhala Russia, mapiritsi 400 mg, mtengo - za 300-360 rubles.

"Tamsulosin": ndemanga madokotala ndi odwala

mankhwala Medical ndi mankhwala zambiri bwino ndi yafotokozedwera mgwirizano mawu chibadidwe osakhala zilonda Prostate zotupa.

Pambuyo 90 masiku zizindikiro anali kusanduka mu 2 zina ndi kusintha woyamba noticeable kale anamuona masiku 14-21. Akamaliza mwa zizindikiro za index mathithi ndi 75% (poyerekeza ndi gawo kuyambira), zomwe ndi chifukwa zovomerezeka.

Wokongola tolerability "Tamsulosin" (kalozera mtengo ndi mankhwala ambiri generic amapatsidwa pamwamba) zimapangitsa izo yabwino kwa ntchito pamene kupatsa odwala mankhwala. Komabe, kukwaniritsa pazipita angathe zotsatira za mankhwala ndi osakwanira, Ndi bwino kuti mankhwala imodzi ndi njira zina ndi mankhwala mankhwala.