Mankhwala "Prestarium": ndemanga za mankhwala

Kukonzekera "Prestarium" - mankhwala ntchito pa matenda a matenda a mtima , ndi ntchito kuchepetsa magazi. Likupezeka pa medicament "Prestarium" ndemanga kutsimikizira nchito zake mankhwalawa matenda oopsa ndi matenda a mtima. pophika wake wamphamvu ndi perindopril ndi mofulumira vasodilatory kanthu ndi kuchepetsa Kugawilidwa kwanthaka wa angiotensin II, amene constricts Mitsempha. Mu ntchito zokhudza zonse za mankhwala wabwezeretsedwa elasticity zikuluzikulu ziwiya wolumikizira, ndipo kuchepa kumanzere yamitsempha yamagazi hypertrophy.

Odwala ndi aakulu mtima kulephera nthawi zambiri amachepetsa mapangidwe subendocardial kolajeni kukonzekera "Prestarium". Mayankho amasonyeza normalizing zotsatira njira kagayidwe kachakudya mu myocytes mtima. Izi mankhwala kumathandiza kuchepetsa preload ndi afterload mtima, ziziyenda uziyenda mwake. Mu zochita za "Prestarium" amatanthauza kuthamanga dontho zidzachitika kudzazidwa ventricles, amene kumachepetsa wonse katundu precardiac. Izi mankhwala ndi woletsa kuti amachepetsa zimachitika ndi kuwonjezeka kusinthasintha kwa mtima kuonjezera zolimbitsa thupi.

Ndi ntchito nthawi yaitali mankhwala "Prestarium" (ndemanga titsimikizire kuti) sikumangotikhudza zili potaziyamu mu ntchito magazi ndi impso. Hypotensive zotsatira za wothandizila umalandira zotsatira pazipita pambuyo maola asanu ndi kumatenga tsiku lonse. Patatha mwezi umodzi, mankhwala mwadongosolo kumabweretsa chosunga olimba a magazi kuti amalimbikira kwa nthawi yaitali. Achire kumapeto kwa kulandira amatanthauza "Prestarium" si anati.

Odwala matenda cerebrovascular amene mosalekeza ntchito mankhwala "Prestarium" ndemanga atsala yekha chiyamiko, kutanthauza kuti mankhwala aukali nthawi zambiri malo imeneyi amachepetsa chiopsezo sitiroko ndi matenda aliwonse katundu mtima. Perindopril alibe mphamvu pa kusintha mlingo kusefera glomerular a impso, kuwonjezera magazi mwa iwo. Izi yogwira chigawo mankhwala mofulumira odzipereka mu magazi pambuyo makonzedwe m'kamwa. plasma ake pazipita ndende chimachitika mu ola pambuyo kumwa mankhwalawa. Perindopril 20% ali n'kukhala perindoprilat yogwira, ndipo okwana bioavailability ndi 70%.

The medicament "Prestarium combi" likupezeka mu magome a mawonekedwe elongate, filimu TACHIMATA, ndi mtundu woyera. Mmodzi mwa anthu amenewo piritsi lili 5 mg wa perindopril arginine lolingana 3,395 mg wa perindopril ndi indapamide 1.25mg. Monga mankhwala othandiza akuwonjezeka mu magome: glycerol, sodium wowuma glycolate, pakachitsulo woipa, magnesium stearate, monogidrad lactose, titaniyamu dioxide, macrogol ndi hypromellose. Tisanayambe mankhwala amafuna dokotala chilolezo ntchito zake.

Pali contraindications ambiri kulandira kukonzekera "Prestarium" (5 mg) anali: mimba, pa mkaka wa m'mawere, kwa chiwindi encephalopathy, kuchuluka kudziwa kukonzekera chigawo, hypokalemia, aimpso kulephera, angioedema. Tikadwala mankhwala, muyenera kusamalitsa ngakhale wake ndi mankhwala ena.