Bacteriophages: zoyimira ndi cholinga

Phage lysis - ndondomeko chiwonongeko cha bakiteriya ndi phages, zambiri amapezeka mu limba anakhudzidwa pa kuchira lachibadwa. Ngati kudziletsa machiritso sichinachitikepo, thupi angathandizidwe ndi powapatsa bacteriophage lolingana, chifukwa mu kampani mankhwala. Otchedwa bacteriophages mavairasi mabakiteriya amene angatithandize ndi chifukwa chakuyimisidwa nchito zawo (lysis) pamsonkhano naye atengeke maselo tating'onoting'ono.

Mu bacteriophage Greek amatanthauza "yodya mabakiteriya." Mu chikhalidwe, zamoyo izi ndi yosiyanasiyana ndipo yaikulu ya pakalipano magulu tizilombo. Phages ndi mavairasi osiyana zomera, nyama ndi dongosolo anthu, kwambiricho. Zikupezeka mu mpweya, mpweya, nthaka, chakudya, khungu nkhani, ubweya nyama Mwachidule, pamene pali mabakiteriya.

M'zaka zaposachedwapa chidwi kukula mu bacteriophages ntchito ngati njira ina mankhwala. Zimenezi n'zosadabwitsa, ndipo iwo ndi mankhwala ena mwachindunji bwanji tizilombo toyambitsa matenda. Komabe, mankhwala amadziwika zingawononge osati pa zomera tizilombo, komanso zofunikira pa. Bacteriophages, mitundu ya zomwe ndi zosiyana, kuchita kusankha okha kuti "awo" mabakiteriya, kusiya wreckage mwa iye. Kwenikweni, kotero asayansi ndipo sanali kuyambitsa maina iwo, zimakhala zosavuta kuwatcha ankalemekeza mabakiteriya amene amachitiridwa.

Bacteriophages: Mitundu

Ndisonyezeni streptococcal, coliform Proteaceae, klebsiellezny, Staphylococcus, Pseudomonas, nsomba, kamwazi, typhoid bacteriophage komanso "Intestifag" ndi "Piobakteriofag".

Kukonzekera yogwira anatsimikiza ndi digiri awo dilution pa zimene lysis tcheru chikhalidwe. Choncho, titer 10 mu mlingo wachiwiri zikutanthauza kuti zinaonetsedwa pa chionetserocho lytic bacteriophage katundu yogwira pa dilution wa 1 000 000 nthawi. Pa kutentha 4-6 C mankhwala iwo kusunga katundu wawo kwa zaka 12.

Malinga mitundu kumasulidwa amasiyana bacteriophages ntchito. Mitundu ya mankhwala zingakhudze toyambitsa munthu aliyense payekha, ndi angapo nthawi imodzi. Monophages bwanji mitundu yambiri ya mabakiteriya chomwecho. K zovuta kukonzekera (polyvalent) monga bacteriophage "Sekstafag" okhoza imodzi ziletsa ntchito staphylococci, streptococci, kuphatikizapo enterococci, Pseudomonas ndi Escherichia coli, Proteus, Klebsiella. Komanso, pali "Intestifag" anafuna kuti mankhwala a matenda matumbo, izo zizindikiro nsomba, typhoid, kamwazi, proteus, coli ndi streptococcal (kupondereza enterococci) phages.

Mankhwala ntchito dysbacteriosis, matenda matumbo, inflammations a dongosolo urogenital ndi zida broncho-m'mapapo mwanga zochepetsera njira septic, komanso matenda a M'mimbamo m'kamwa ndi sinuses. Iwo ntchito monga mkati, kuphatikizapo mu mawonekedwe a enemas, ndiponso kwanuko - kuti muzimutsuka, kuchapa mabala, douching. Mwachitsanzo, "The Bacteriophage Klebsiella polyvalent mwayeretsa" zochizira ozeny, rinoskleromy, matenda oyamba ndi bakiteriya Klebsiella chibayo, ntchito ndi inhalation pa zotupa trachea, m'phuno ndi pharynx, kutumikiridwa turunda ankawaviika madzi, otitis, ntchito washings mu sinusitis. Pamene cystitis, enterocolitis, urethritis, chibayo mankhwala akutengedwa pakamwa.

Bacteriophages ndi unyinji wa ubwino pa mankhwala. Iwo ndi zotsatira palibe mbali, akutumikira ngakhale ana ndi amayi apakati, si osokoneza. Iwo akhoza pamodzi ndi mankhwala alionse, komanso ntchito kupewa matenda opatsirana. Kukonzekera awa ndi chikoka opindulitsa pa chitukuko cha chitetezo chokwanira, musati kupondereza zomera zachilengedwe ndi mmene zimaonekera mwa maola 2-4 pambuyo ingestion. Iwo bbwino kukana tizilombo toyambitsa matenda.

drawback umodzi bacteriophages. Mitundu ya ntchito lero mankhwala, koma ochepa, zomwe zimasokoneza ntchito zawo matenda ambiri.

ntchito Outlook

Kuti bwinobwino ntchito mankhwala kwachilengedwenso, m'pofunika kudziwa tilinazo mabakiteriya kwa iwo. Komabe, asayansi aona citsanzo chidwi: tilinazo tizilombo kuti phages si yafupika, koma kumawonjezera, chifukwa patsogolo katundu ndi chikhalidwe chatsopano. Pakali pano, ndi staphylococcal bacteriophage bwinobwino lyse 90% tizilombo ta onse mabakiteriya anamasulidwa pa zotupa septic.

Ambiri nthenda akatswiri amakhulupirira kuti phage mankhwala posachedwapa atapeza polimbana ndi matenda. Immunologists kuona chiyembekezo cha ntchito ndalama awa kumene Immunopreparat mphamvu. Malinga ndi maphunziro mawunikidwe mu zaka zingapo zotsatira, mmodzi wa m'madera ambiri zingamuthandize kamwedwe ka mankhwala adzakhala yopanga phages.