Mankhwalawa "Doxycycline", ofanana ndi zochita zawo.

"Doxycycline" imatanthawuza maantimicrobial kuti agwiritsidwe ntchito. Monga Doxycycline wokha, zifaniziro za mankhwalawa ndi mbali ya gulu la tetracycline. Ali ndi njira zambiri zolimbana ndi tizilombo toyambitsa matenda.

Mafano otchuka kwambiri a mankhwala "Doxycycline" ndi "Unidox solute", "Doxycycline gidlochloride", "Doxibene", "Doxycycline-darnitsa" ndi ena ena. Nthawi zambiri mumatha kuona momwe munthu amakayikira zomwe angagule, "Doxycycline" kapena "Unidox", mwachitsanzo. Tiyenera kukumbukira kuti mankhwala osokoneza bongo a mankhwalawa ndi ofanana. Choncho, onsewa amagwira ntchito yogwirizana ndi Gram-positive (Stamphylococcus spp., Streptococcus spp., Actinomyces Israeli, Clostridium spp., Listeria monocytogens, Bacillus anthracis) ndi Gram-negative (Neisseria gonorrhoeae, Vibrio cholerae, Bordetella pertussis, Yereinia spp., Enterobacter spp. Klebsiella spp., Escherichia coli, Salmonella spp., Shigella spp.) Wa tizilombo toyambitsa matenda. Amagwirizana ndi Doxycycline ndi mafananidwe anga a Mycoplasma spp., Rickettsia spp., Treponema spp., Borrelia burgdorferi, Chlamydia spp., Ena a protozoa (kuphatikizapo Entamoeba histolytica, Plasmodium falciparum). Zomwe zimakhudzidwa kwambiri ndi mafananidwe a "Doxycycline" Haemophilus influenza (91-96%) ndi tizilombo toyambitsa matenda.

Chokhacho chokhacho, chosiyana ndi mankhwala omwe amachititsa kuti "Doxycycline" agwiritsidwe ntchito - ndi ochepa kuposa antchito ena a tetracycline omwe amawononga kwambiri matumbo a m'mimba, komanso amakhala ndi nthawi yayitali komanso kuyamwa kwathunthu. Maantibayotiki omwe amachokera ku tetracyclines amalowa m'kati ndikusokoneza kubereka kwa tizilombo toyambitsa matenda komweko. Malingana ndi kuchuluka kwa ntchito ya bakiteriya, mankhwala "Doxycycline hydrochloride" amaposa tetracyclines ena onse, kuphatikizapo zachirengedwe.

Monga mankhwala "Doxycycline," mafananidwe ake ali ndi zizindikiro zotsatirazi zogwiritsidwa ntchito:

- ziwalo za ENT zopatsirana;

- matenda a mphutsi;

- kachilombo koyambitsa matenda ;

- Matenda a ziphuphu zofewa ndi khungu;

- matenda a biliary ndi m'matumbo;

- osteomyelitis, brucellosis, chifuwa chachikulu;

-syphilis, yersiniosis, malaria, maws, ky fever, legionellosis, typhus, rickettsiosis, matenda a Lyme, chlamydia a m'madera osiyanasiyana, bacillary ndi amoebic wamagazi, kolera, tularemia, actinomycosis;

- mu mankhwala ambiri - granulocyte erlichiosis, leptospirosis, psittacosis, trachoma, ornithosis;

- yotsutsa septic endocarditis, sepsis, peritonitis.

Kuletsa kugwiritsa ntchito "Doxycycline" ndi mphamvu ya tetracyclines, kuopsa kwa chiwindi, porphyria, panthawi ya mimba, lactation (panthawi yomwe kumwa mankhwala akuyamwitsa ayenera kusiya), ali ndi zaka zosapitirira khumi ndi ziwiri. Mosamala muyenera kumwa mankhwalawa kwa anthu omwe akuphwanya chiwindi, leukopenia.

Mankhwalawa "Doxycycline" akhoza kukhala ndi zotsatirapo pa:

- dongosolo la mitsempha (poizoni m'katikatikati mwa mitsempha ya m'mitsempha, kupanikizika kosagwira ntchito pamwambapa);

- Kumva ziwalo (phokoso limapezeka m'makutu);

- kumayambitsa matenda (enterocolitis, kusanza ndi kunyoza, kutsekula m'mimba kapena kudzimbidwa, gastritis, dysphagia, glossitis, esophagitis, kufotokoza kwa m'mimba ndi duodenum);

- kuchokera kumbali ya mtima (edema, tachycardia);

- hematopoiesis (thrombocytopenia, eosinophilia, hemolytic anemia, neutropenia, porphyria);

- zowonongeka (kutuluka khungu, kuyabwa , kuyamwa kwa anaphylactoid, kuthamanga kwa maculopapular, matenda a Stevens-Johnson, edema anti-neuropathy);

- Ena (hepatitis, jaundice, myalgia, arthralgia, photosensitization, kutuluka kwazitsulo kolimba kwa dzino, kutupa kumalo a anogenital zone, candidiasis, dysbiosis).

Mukadakhala ndi overdose wa Doxycycline, mukhoza kuzindikira zizindikiro zotsatirazi: hepatotoxicity, zotsatira zowonjezereka. Pachifukwa ichi, nthawi yomweyo muyenera kupita kuchipatala, kuchotsa mankhwalawa ndi kuchiritsa mankhwala (chifukwa palibe mankhwala enieni), ndifunikanso kusunga ndi kuyang'anira momwe ntchito yofunikira ikuyendera.