Mankhwala "Acyclovir-Akos" (mapiritsi). Malangizo ntchito ana ndi akulu, ndemanga

Mu mlingo wa mankhwala akuchipatala, "Acyclovir-Agos"? Malangizo ntchito mapiritsi awa anapereka m'munsimu. Komanso, mudzaphunzila chifukwa ntchito chida ichi, ngati iwo ali ndi zovuta zilizonse ndi contraindications, ali m'gulu kapangidwe kake, ndipo mu phukusi zimene zimakhalira Akugulitsa.

Zikuchokera, maonekedwe, ma CD mankhwala

Amene zigawo lili "Acyclovir-Agos" (mapiritsi)? Malangizo Ntchito limanena kuti yogwira zikuluzikulu za mankhwala ndi acyclovir. Ndiponso limapangidwa ndi zinthu zina monga talc, magnesium stearate, ndi wowuma mbatata.

"Acyclovir-Agos" - mapiritsi (maganizo wodwalayo kuti tifotokoze) Valium woyera ndi Valium ndi mbali. Mu kugulitsa mankhwala akulowa maselo mizere kuti anayikidwa mu katoni. Komanso, mankhwala awa akhoza kupezeka mu mtsinje wa galasi mdima.

The pharmacological katundu wa mankhwala

Kodi "Acyclovir-Agos" (mapiritsi)? Malangizo Ntchito limanena kuti antiherpetic mavairasi oyambitsa wothandizira. Izi mankhwala ndi kupanga purine nucleoside analogue. Iye akhoza ziletsa kugawanika tizilombo wa nsungu simplex, cytomegalovirus, ndi Epstein-Barr HIV ndi Varicella zoster.

Features mankhwala

Malinga ndi akatswiri, "Acyclovir-Agos", ndemanga zimene ziri zabwino mokulirapo, izo zikusonyeza ntchito yabwino tizilombo timene timayambitsa nsungu zoster, ndi katsabola.

Pa kulandira medicament m'zipinda kachilombo phosphorylation akuyamba. Acyclovir ali n'kukhala monophosphate acyclovir. Mothandizidwa omaliza guanylate cyclase ali n'kukhala diphosphate amene nawonso, ndi kutembenukira ku triphosphate lapansi.

Zotsatira kusankha mankhwala pa kachilombo koyambitsa, komanso kawopsedwe ake otsika lake chifukwa chakuti pophika ake yogwira si gawo lapansi kwa enzyme thymidine kinase. Pa nkhani imeneyi, si poizoni kuti maselo zolengedwa zoyamwitsa.

Atatembenuka kuti acyclovir acyclovir triphosphate izo kumabwezera mmbuyo kaphatikizidwe wa tizilombo DNA 3 zimagwirira:

• m'malo deoxyguanosine triphosphate;
• Integrated mu unyolo DNA, kenako umatha elongation ake;
• kumafooketsa pa DNA ya nsungu simplex ndi zina zotero.

Chifukwa cha kukhudzana ngati kugwira HIV kuchokera kugawikana.

acyclovir Mwachangu ndi chifukwa kudzikundikira ake maselo amene kale ndi kachilombo HIV. Herpes mankhwala kumathandiza mapangidwe zotupa yatsopano, ndi olimbitsa mabala, kuchepetsa ululu ndi ali zimakhudzanso immunostimulating.

magawo Pharmacokinetic mapiritsi antiherpetic

Kodi mayamwidwe chikuchitika "Acyclovir-Agos" mankhwala? Malangizo ntchito limanena kuti makonzedwe m'kamwa ndi mu pang'ono imatsala ku intestine lapansi. Mu mawonekedwe zimenezi ndende (mlingo amadalira), amene ali okwanira kwambiri kuti mankhwala bwino matenda tizilombo.

Chakudya ali pafupifupi ziribe mphamvu pa mayamwidwe wa chinthu yogwira. Ndi kukula Mlingo wa bioavailability wa amachepetsa mankhwala.

Ndende pazipita mankhwala pambuyo ikupita m'kati mwa kuchuluka kwa 200 mg 5 nthawi patsiku ndi 0,75 g / ml, ndi osachepera - 0,45 g / ml. Chiwerengerochi kuti patapita maola awiri.

Madzi a m'magazi mapuloteni yogwira pophika chimamanga kuti 10-35%. Iwo likulowerera magazi ubongo chotchinga, komanso pafupifupi zimakhala onse ndi ziwalo (m'mapapo, mu ubongo, madzimadzi lacrimal, impso, intestine, chiwindi, minofu, nthabwala amadzimadzi, mkaka wam'mawere, umuna, ndulu, madzimadzi amniotic, chiberekero, obisika ndipo zimagwira ntchito zosiyanasiyana mucous kumaliseche kwa mkazi, komanso nkhani za vesicles herpetic).

kagayidwe mankhwala chiwindi. Izi ndipamene metabolite 9 otchedwa karboksimetoksimetilguaninom.

Anasonyeza medicament kudzera impso (62-91% ya mlingo) ndipo mwa mundawo m'mimba. Mbiri tochepa mankhwala ofunitsitsa ndi wotuluka tikamapuma ndi wodwalayo.

Pamene kulandira mankhwala mkati ake theka moyo (akuluakulu) ndi - maola 3.4, ndi ana (zaka 1-18) - maola 2.4. Choncho tikhoza kuona kuti mlingo wa excretion wa mankhwala kubweza ndi zaka.

zikuonetsa medicament

Pamene kutumikiridwa "Acyclovir-Agos"? Kugwiritsa ntchito mankhwala akusonyeza kuti kupewa ndi mankhwala a matenda oyamba ndi mavairasi Varicella zoster ndi Herpes simplex (mitundu 1 ndi 2). Choncho, mankhwala bwino amachitira:

• nsungu simplex khungu ndi mucous nembanemba (pulayimale ndi kobwereza);
• nsungu zoster;
• maliseche nsungu (pulayimale ndi kobwereza);
• nsungu zoster;
• varicella (tsiku loyamba pamene totupa limapezeka).

Iwo ayenera kukumbukira kuti ntchito mankhwala Kwalamulidwa kwa odwala immunodeficiency aakulu (mwachitsanzo, anthu amene ali ndi HIV, kumuika ndi pamene mukumwa mankhwala immunosuppressive).

contraindications

Mu zina, linaletsa ntchito "Acyclovir-Agos" (mapiritsi)? Atsogolereni mfundo contraindications zotsatirazi:

• zaka ana (zaka zitatu);
• hypersensitivity kwa thunthu yogwira, komanso anafotokoza kuti valacyclovir.

Mosamala kwambiri, mankhwala Kwalamulidwa woyembekezera, kulephera aimpso ndi ludzu, komanso nthawi yoyamwitsa.

Mankhwala "Acyclovir-Agos": bwanji kuti akulu?

mapiritsi ayenera kumwedwa pakamwa, mosatengera chakudya ndi madzi kumveka.

Akuluakulu zochizira nsungu simplex HIV nembanemba wa mucous ndi khungu Kwalamulidwa 200 mg wa mankhwala kasanu patsiku. Makhwalawa akhale mawola anayi (kupatula kugona).

Childs, nthawi ya mankhwala kukonzekera awa ndi masiku asanu. Koma ngati n'koyenera, izo chikhonza kuwonjezeredwa (malinga ndi malangizo adokotala).

Mankhwalawa anthu ndi immunodeficiency mlingo umodzi wa mankhwala linawonjezeka 400 mg, ndi nthawi kumene ya - masiku khumi ndi zambiri.

odwala wamkulu ndi nsungu maliseche bwino kutenga mankhwala pa 200 mg kasanu tsiku (mawola anayi) kwa masiku 10 (ngati mankhwala ofunika angathe). Chithandizo ayenera kuyamba posachedwapa pambuyo pakutchulidwa zizindikiro woyamba wa matenda. Ngati pali kumwa, mankhwala Kwalamulidwa kale mu nthawi prodromal.

Kuletsa zisadzachitikenso matenda amene amayamba ndi nsungu simplex HIV, mankhwala zotchulidwa 200 mg kanayi pa tsiku (mawola asanu). Anthu ndi chitetezo chokwanira zimaikidwa ntchito mankhwala ndi kuchuluka kwa 400 mg kawiri pa tsiku (mawola 12). Pamene asonyeza immunodeficiency mlingo akanali yemweyo, koma pafupipafupi ndi kuchuluka kwa kasanu patsiku.

Kobwereza maliseche nsungu (nthawi zisanu ndi chaka) ayenera kutsatira kamwedwe zotsatirazi: 200 mg kasanu pa tsiku kwa masiku asanu. Ngati zochititsa abwerezedwa nthawi zoposa zisanu chaka, mtima wa Kwalamulidwa 400 mg wa mankhwala kawiri pa tsiku kwa miyezi 12. Kutalika kwa prophylaxis nthawi anatsimikiza ndi nthawi ya nthawi, pamene matenda.

Mankhwalawa nsungu zoster kapena zoster mtima kutumikiridwa 800 mg wa mankhwala kasanu patsiku (mawola anayi) kwa masiku 7-10.

The pazipita umodzi mlingo wa mankhwala ndi 800 mg.

Anthu kutenga mlingo waukulu wa mankhwala ayenera kulandira wambirimbiri madzi.

"Acyclovir-Agos" (mapiritsi): malangizo kwa ana

Makanda, amene zaka wafika zaka zitatu, mankhwala ayenera kuperekedwa pokhapokha madokotala odziwa. Kawirikawiri, mlingo kwa iwo ndi ofanana ndi mlingo wa akuluakulu.

Mankhwala katsabola ana zaka zoposa zisanu ndi chimodzi kupereka 800 mg wa mankhwala kanayi pa tsiku, ndi mwana zaka 3-6 - 400 mg kanayi pa tsiku. Kwa lachindunji kuposa n'zimene madokotala amagwiritsa ntchito mfundo zotsatirazi: 20 mg wa pa makilogalamu thupi mwana. Tengani medicament oposa 800 mg wa kanayi pa tsiku ndikoletsedwa.

Nthawi mankhwala odwala achinyamata masiku asanu.

Mu anthu ndi ntchito mkhutu impso mufunika kusintha mlingo, komanso kulandira pafupipafupi. Izo zimatengera mtundu wa matenda ndi makhalidwe a creatinine chilolezo.

mavuto pambuyo ingestion a mapiritsi

Medicament "Acyclovir-Agos" kawirikawiri amayambitsa zotsatira zina zoyipa. Koma, malinga ndi malangizo, ali ndi malo kukhala.

1. Nseru, kuchuluka bilirubin zizindikiro, kutsekula m'mimba, kupweteka m'mimba, kusanza, kusintha kuwonjezeka michere chiwindi.
2. Pachimake aimpso kulephera ndi wapamwamba seramu creatinine misinkhu mu magazi ndi urea.
3. Leukopenia, kuchepa magazi, thrombocytopenia.
4. Mutu, kuyerekezera zinthu m'maganizo, matenda a ubongo, kusintha Kusokonezeka m'maganizo, chizungulire, paresthesia, kugona, chikomokere, khunyu.
5. Totupa, dyspnoea, photosensitivity, angioedema, zidzolo, malungo, pruritus, lymphadenopathy, anaphylaxis, mukubwadamuka, kusawona bwino, edema zotumphukira, myalgia.
6. Kutopa, alopecia.

Iwo ayenera kukumbukira kuti anthu alandire mankhwala ochepetsa, madyedwe zina mankhwala "Acyclovir-Agos" sichiyambitsa kuwonjezeka kwambiri zotsatira poizoni.

ayamikira enieni kugwiritsa ntchito ndalama antiherpetic

Kodi mukufuna kudziwa pamaso kutenga "Acyclovir-Agos" (mapiritsi)? Malangizo limanena kuti yaitali kapena mobwerezabwereza mankhwala a anthu ndi udindo m'thupi yafupika zingachititse kuti pakhale tizilombo ta HIV amene sanakhudzidwe ndi kanthu ake.

Chipatala chitetezo maphunziro kugwiritsa ntchito mankhwala pa mimba sadafikeko. Pa nkhani imeneyi, kugwiritsa ntchito mankhwala "Acyclovir-Agos" Titha kokha pamene phindu kuthekera kwa amayi ndi wamkulu kwambiri kuposa chiopsezo kuthekera kwa mwana wosabadwayo.

Mankhwalawa Mlingo mkulu m'kamwa kwa wodwala ayenera kumwa zedi okwanira madzi.

Pa yoyamwitsa mankhwala anatumizidwa pokha pokha kwambiri, kanthawi ndithu. Ichi ndi chifukwa chakuti mankhwala wochepa mu mkaka wa m'mawere.

Medicament "Acyclovir-Agos" samaletsa kufala kwa nsungu opatsirana pogonana. Pa nkhani imeneyi, m'nthawi ya chithandizo, wodwala ayenera atapewa kugonana.

Reviews odwala pa mankhwala

Tsopano inu mukudziwa bwanji ndiponso kuti mankhwala mankhwala "Acyclovir-Agos". malangizo ntchito ya kalozera njira wakhala anafotokoza pamwamba.

Malinga ndi ndemanga ambiri odwala malipoti mankhwala bwino kumaonekera zilonda. Ngati inu kutenga mankhwala yomweyo pambuyo kupeza zizindikiro loyamba nsungu, kuchira wodwala adzakhala mofulumira kwambiri.

Iwo ayenera kukumbukira kuti "Acyclovir-Agos" mwaluso amachitira matailosi ndi katsabola.

Kuwonjezera mankhwala mankhwala amene amagwiritsidwa ntchito ngati muyeso njira. luso lake lamanja kumathandiza kuchepetsa chiwerengero cha musabise yochepa.

Mtengo wa mankhwala

Tiyeneranso kuti kuwonjezera pa mkulu dzuwa mankhwala "Acyclovir-Agos" odwala osangalala ndi ndalama zawo wotsika. Kugula mapiritsi 20 antiherpetic mungathe kwa 30-40 rubles Russian. Mwachindunji kuchuluka Kumkwanira njira ya chithandizo.

Zodabwitsa ndizakuti, yemweyu ali ndi mtengo wotsika ndi analogues wa mankhwala.