"Lopedium" Mapale: malangizo Buku, ndemanga

"Lopedium" - mankhwala ogwetsa peristalsis. Ndi gelatin kapisozi ndi chipolopolo yovuta, utoto imvi kapena mdima mtundu wobiriwira (iwo ali ndi yochitidwa homogeneous ufa) kapena miyala woyera.

katundu pharmacological

Miyala "Lopedium" (malangizo ntchito anapatsidwa m'nkhani ino) amapangidwa ndi zinthu zina zimene mungakumane ndi maselo matumbo opiate. Kudzera kugwirizana kuti akulephera kutuluka kwa acetylcholine ndi prostaglandin. Mu njira imeneyi zimachitika yafupika kumawonjezera peristalsis ndi osakhalitsa kusiyana Ndime ya chakudya kudzera thirakiti m'mimba kwambiri. Komanso malinga matumbo kuyamwa madzi zinabwera kamvekedwe ka minofu sphincter.

Pharmacokinetics

Ambiri loperamide, analowa thupi odzipereka mu matumbo Komabe, chifukwa tima kagayidwe loyamba wapita, zokhudza zonse bioavailable chabe kotala peresenti a.

Mwa kufufuza izo wapezeka kuti mankhwala ndi anagawira ndi ulemu khoma matumbo, chotero chimamanga kwa maselo kotenga akulu odula wosanjikiza. Makamaka loperamide chimamanga kuti mapuloteni, makamaka albumin.

Miyala "Lopedium" (malangizo Buku m'gulu iwo mankhwala otetezedwa) pafupifupi mwathunthu chosakanikirana ndi chiwindi, kumene zimapukusidwa, conjugated ndi excreted mu ya ndulu ya. Chifukwa zotsatira kwambiri kwambiri kwa Ndime yoyamba kudzera yokonza chiwindi, ndende ya mankhwala magazi kwambiri yafupika, pamene otsala otsika kwambiri. Mankhwala kwathunthu excreted kudzera khumi - khumi maola.

zikuonetsa

"Lopedium" (mapiritsi) malangizo Buku akuonetsa kuti mu nkhani ya m'mimba aakulu ndi pachimake. Izi mankhwala angathe kuperekedwa kwa anthu amene amayenda ( "alendo m'mimba"). Pankhaniyi, mankhwala ayenera kukhala masiku awiri. Komabe, mu nkhani ya kudziwika magazi m'manyi Sikuti ntchito mankhwala kudziwa zimene zimayambitsa matenda dokotala.

contraindications

Musagwiritse ntchito miyala kukachitika kuti pali hypersensitivity kuti hydrochloride loperamide kapena zigawo ina lokonzekera.

The contraindications chachikulu odwala:

- bakiteriya enterocolitis, chifukwa ntchito tizilombo ena:

- pachimake kamwazi, limodzi ndi m'mimba wamagazi ndi malungo.

Yonseyi mankhwala ndi mankhwala aliyense ayenera mosamala kwambiri. Onetsetsani kuti auzeni adokotala.

Musagwiritse ntchito mapiritsi "Lopedium" (malangizo Buku limatichenjeza odwala) mu chitukuko cha kudzimbidwa, bloating kapena kutsekeka m'matumbo. Pewani ndalama ngati n'koyenera kupewa kupondereza peristalsis.

Kodi kutenga "Lopedium" mapiritsi

Mankhwala angagwiritsidwe ntchito akulu ndi ana okulirapo kuposa zaka zisanu ndi chimodzi. Kapisozi (piritsi) ayenera kuwameza lonse ndi madzi pang'ono woyera.

Mu aakulu pachimake m'mimba mlingo aakulu pakati 4 mg ndi chiphunzitso (ma PC awiri.). Ana Kumkwanira chidutswa chimodzi. mankhwala ayenera kumwedwa nthawi iliyonse chopondapo lotayirira. Zolemba malire mlingo tsiku ana ndi akulu ndi miyala sikisi eyiti.

Ngati zizindikiro pachimake m'mimba kutha pasanathe maola forte-eyiti, mankhwala ayenera kusiyidwa.

odwala achikulire safuna zisoti wapadera mlingo kusintha. Yemweyo amapita anthu odwala matenda a impso. "Lopedium" (mapiritsi) malangizo Buku si amalangiza kupatsa ana zaka 3 zakubadwa.

Features ya ntchito

Nthawi zambiri, chithandizo cha m'mimba ndi mwadongosolo. Ngati wodwala ali ndi mwayi chimatanthauza etymology cha matenda, mu nkhani iyi ndikofunikira kugwira mankhwala enieni. N'zotheka kuti mankhwala zotchulidwa dokotala pa ntchito mankhwala opha tizilombo. Limodzi ndi phwando amatanthauza "Lopedium" (mapiritsi) malangizo ntchito ana akuonetsa m'malo mankhwala kubwezeretsanso electrolytes ndi madzi. Izi zichitike kukachitika kuti pali vutoli wa electrolytes ndi ludzu.

Odwala amene anapezeka kuti anapeza immunodeficiency syndrome (AIDS), kutsegula m'mimba ayenera yomweyo siyani kumwa "Lopedium" vuto la bloating.

"Lopedium" (mapiritsi): Malangizo ntchito pa mimba ndi yoyamwitsa

Madokotala sali amalangiza kumwa mankhwala kwa akazi apakati ndi lactating. Ichi ndi chifukwa chakuti wochepa loperamide angaoneke mu mkaka wa m'mawere. Icho ndicho chifukwa akazi "mu boma" inayenera dokotala musanagule mankhwala.

Mogwirizana ndi mankhwala ena

Asayansi milandu mogwirizana ndi mankhwala amene ofanana makhalidwe pharmacological. Mankhwala amene ali ndi zotsatira nkhawa pa chapakati mantha dongosolo, sakhoza pamodzi "Lopedium".

Dziwani kuti loperamide - ndi gawo lapansi ya P-glycoprotein. Munthawi yomweyo ntchito 'Lopedium "ndi quinidine ndi ritonavir angachotsedwe kuwonjezeka kwambiri mu ndende mwazi wa mankhwala. Mlingo akhoza ziwonjezeke kwa nthawi ziwiri kapena zitatu. A kuchita chimodzimodzi unkachitika pamene itraconazole ndi ketaconazole.

Iwo wapezeka kuti mankhwala ndi ofanana katundu pharmacological mwina patsogolo ntchito ya kangapo loperamide. Koma mankhwala kufulumizitsa ndondomeko ya kudutsa nkhani za mundawo m'mimba M'malo mwake, kuchepetsa nchito zake.

ambiri osokoneza

Miyala "Lopedium" (malangizo ntchito anafotokoza zizindikiro za mankhwala osokoneza bongo) zingachititse kuti imfa ya kuyenda, mutu, somnolence, stupor, ndi posungira mkodzo. Ngati mwapeza ndi zizindikiro zofanana, mungachite "Naloxone". Nthawi zina, m'mimba kusamba ndi kumwa adamulowetsa makala.

zosiyanasiyana chokhwima

Pa totupa pakhungu ungadzakhazikitsidwe, kuphatikizapo matenda Stevenson-Johnson; erythema multiforme; kutupa; kuyabwa ndi ming'oma.

Mankhwala zingathe kusokoneza pa wamanjenje dongosolo. Odwala nacho tulo, kutayika kwa mugwirizano, imfa ya chikumbumtima, matenda oopsa, ndi kugwedeza.

Ku dongosolo m'mimba, odwala muzindikire youma pakamwa, kudzimbidwa, nseru, flatulence, kusanza, ileus. odwala ambiri anali kutopa.

Ndi kusamala kwambiri ayenera kugwiritsidwa ntchito madalaivala mankhwala ndi makina ntchito, monga mankhwala zingachititse kusinza.

mawonekedwe kumasulidwa, zikuchokera ndi wazolongedza

Aliyense kapisozi (piritsi) lili mamiligalamu awiri hydrochloride loperamide. Kuwonjezera mankhwala waukulu ndiponso kukonzekera muli wothandiza chamtendere, talc, magnesium stearate, chimanga wowuma ndi lactose monohydrate.

Anagulitsa mapilitsi mu mbale, zidutswa khumi. phukusi zingakhale za matuza wina ndi asanu.

miyala ndi mtundu woyera ndi mawonekedwe zozungulira, otukukira kunja mbali imodzi.

mankhwala ziyenera kusungidwa mu mdima, youma patali ana. Kutentha sayenera upambana madigiri twente-faifi. alumali moyo - zaka zisanu kuchokera tsiku kupanga. mankhwala zikhoza kugulidwa pa mankhwala iliyonse popanda dotolo. Koma musaiwale kuti ankadzionetsera angakhale ndi zotsatira zoipa.