Cushing's syndrome: matenda, matenda, matenda

Matenda a Cushing akuwoneka ngati akuwonjezeka pamtundu wa glucocorticoids mu adrenal cortex. Matendawa amapezeka mwa amayi nthawi zambiri. Chifukwa chofala kwambiri cha matendawa ndi kuwonjezeka kwa mavitamini a ACTH (adrenocorticotropic hormone), yomwe imakhudza ntchito ya adrenal cortex ndipo imayambitsa kuwonjezeka kwa mahomoni. Kawirikawiri kutulutsa kwakukulu kwa adrenocorticotropic hormone kumayambitsa chifuwa chachikulu, ndipo nthawi zina ndi chotupa cha ziwalo zina. Matendawa amatha kukhala ndi kayendedwe kake kakang'ono ka ma steroid okonzekera omwe ali ndi cortisone, kapena othandizira omwe ali ndi ACTH (omwe amagwiritsidwa ntchito kuchepetsa ntchito yoteteza thupi kumatenda opangira thupi).

Cushing's Syndrome: Zizindikiro

Umoyo wathanzi ndi kugonana kumakhudza zizindikiro za matendawa. Zizindikiro zofala za matendawa ndi izi:

• Phindu lolemera. Mafuta akuwonjezeka pamaso ndipo makamaka kumbuyo kumbuyo;
• Stria (kutambasula) pamimba, chifuwa, manja ndi ntchafu;
• Maonekedwe a kuvunda, kupukuta khungu;
• Mabala ochiritsa osauka;
• Katemera wathanzi pambuyo pa matenda oopsa opatsirana;
• Kufooka, kutopa;
• Nkhawa, kugona;
• Kukhumudwa kwakukulu;
• Mutu wamutu;
• Kuchepetsa kukumbukira ndi malingaliro;
• Kwa amayi, kusamba kwachedwetsedwa;
• Kusiyana kwa shuga, komwe kumayambitsa matenda a shuga;
• Kuthamanga kwa magazi.

Cushing's syndrome: matenda

Matenda oyambirira angapangidwe chifukwa cha zizindikiro za matendawa. Kuti mupeze chithandizo chodalirika, kufufuza kwakukuluko kumafunika, mothandizidwa ndi zomwe zimayambitsa Cushing's syndrome. Kuti muchite izi, nkofunikira kuyambitsa mkodzo ndi kudziwa kuchuluka kwa cortisone. Kafukufuku wina akusonyeza kuyesa wodwalayo ndi mayeso a dexamethanosone, omwe wodwalayo amadya 2 magalamu. Dexamethasone, ndipo pambuyo pa maola 9 cortisone mu plasma imayesedwa.

Kuti mudziwe zomwe zimayambitsa Cushing's syndrome, mlingo wa ACTH umayesedwa. Kotero, msinkhu wokwera wa hormoni ukhoza kuyankhula za kutayika kwa adrenals, ndipamwamba kwambiri - za kusokonezeka kwa hypophysial.

Cushing's syndrome: mankhwala

Chithandizo chodziwika bwino komanso chothandiza cha matendawa ndichosankha transsphenoidal adenomectomy. Ngati maphunzirowa adatha kuzindikira malo enieni a chifuwa cha mankhwalawa, njira yothandizira anthu odwala matendawa amachitidwa. Njira iyi siingagwiritsidwe ntchito ngati wodwala ali ndi mtundu woopsa kwambiri wa matendawa kapena ali ndi matenda osokoneza bongo.

Njira ina yothandizira ndi chiwonongeko cha adrenal glands. Kupyolera mu kuyambitsa mankhwala osokoneza bongo amatha kuthetseratu mankhwala ophera thupi. Njirayi imagwiritsidwa ntchito pogwiritsa ntchito njira za ultrasound ndi CT.

Palinso njira yothandizira matenda a Cushing, monga mankhwala a proton. Njirayi imagwiritsidwa ntchito ngati palibe njira zodalirika za chifuwa cha mankhwala opatsirana. N'zotheka kuthetsa matendawa. Pachifukwa ichi, ndalama zimagwiritsidwa ntchito zomwe zimaletsa kupanga ACTH. Thandizo lachidziwitso lothandizira pa matenda a shuga, matenda a shuga, ndi matenda odwala matendawa amachitanso. Nthaŵi zina, njira yothandizira ma radiation ingagwiritsidwe ntchito. Matenda a Cushing amatanthauza kumwa mankhwala osokoneza bongo , bisphosphonates, mavitamini ndi mankhwala ena. Matendawa ndi osavuta kuchiza ndipo poyambira matendawa amayamba kuchepa.